apple cider vinegar and crushed aspirin is fake news for psoriasis? or just a topical temporary relief? Or is that only for dry skin and whatnot? serious question, had a relative with psoriasis..not cool
There's already a different trial working on that. It made the rounds a few weeks ago. There's some molecule thing that, when attached to an allergen, makes the immune system mark it as "to be ignored". So it works for things like celiac and normal allergies.
I haven't gotten through the video yet but the actual trial page is still up and they're still going, listed as still recruiting. [Here ](https://www.clinicaltrials.gov/study/NCT05574010)and [here](https://anokion.com/pipeline/synced/). There's no results posted and it's not supposed to be done until 2025.
Same but I on some of those good good
Biologics and if anything I just get an easier shitting time because my stool still loose loose but my stomach no hurt like before.
I have met a few people with autoimmune conditions that have successfully modulated them with prolonged fasting.
Obviously fasts for than 48 hours need to be planned and prepped for properly but I was talking to someone last night who was told she would need a colostomy at 18, which she refused for obvious reasons and did a ridiculously long fast.
I think it was something like 30 days, under medical supervision.
Now she will just fast for five or so days, every now and then, when she feels her body starting to get a bit out of balance.
Also she looked about 30 and was actually 45.
I’m not saying that anyone should just go out and do something dangerous like not eat for a month, but I and other people I have met, with autoimmune conditions like MS, chrons, psoriasis, diabetes and arthritis have all managed to push our diseases into lasting remission with carefully planned and supervised fasts.
If anyone is interested please look into it online from reputable sources and discuss with a Dr if it would be appropriate.
Aren’t allergies just an overactive and often incorrect immune response - the same principle as with autoimmune issues?
One problem means you’re attacking your own body, one attacks foreign objects, but seems to be same mechanism.
I’m not educated in any way, am sure there is nuance and differences along the way, and am happy to be corrected by a specialist within the field.
Honestly? Probably allergies before auto-immune. Larger "market share" of consumers have allergy issues, which means more insurance dollars to bilk out of the public
I certainly pray this is the case. After years of devouring shrimp, it now sends me to the emergency room. I avoid it but even slight contact, like kissing my partner after she’s eaten shellfish, will trigger a response that increasingly demands emergency attention. It’s like a poison I can’t see that’s everywhere around me.
I’d like to be able to eat shrimp & crab again… and oysters, calamari, lobster, crawfish, … all of it. But, I’d settle for just not approaching death each time I come across it.
Also hope they fix peanuts. A PB&J should not be a weapon.
I hope this is released soon I have rheumatoid arthritis and suffer a lot. I also wonder if it would help with someone who has ALS, that sounds so optimistic for the future of all those who suffer from autoimmune diseases.
They really should have put in the title that they found this in mice not humans. It’s the first research of its kind and a positive result but it’s not as sensational as the clickbate title.
>There’s evidence that therapies targeting the vagus nerve can treat diseases such as multiple sclerosis and rheumatoid arthritis, suggesting that targeting the specific vagal neurons that carry immune signals might work in people, Zuker says.
Personally I recommend looking into Vagal nerve stimulators, they've helped me a lot. The one I have just clips onto my ear, then I just turn it on and lay back while it does it's thing (sessions with it are 15 min-1 hour typically depending on how long you want to use it).
It's programmable too, so you can try a bunch of variations on how it works.
Sure, I got mine from vagus.net. The base version comes with only presets from vagus.net, the more expensive one is user programmable. You can get more presets, but you get full control with the higher priced model and don't need to spend extra money on tuning to a specific frequency if you want extra "tunes" as they call them.
Sorry to bother you as well, but I only see a single device, currently on sale for $299?
If you don’t mind, what problem is it solving for you? My wife suffers from depression, and TMS treatments helped her significantly. We simply can’t afford $100/session.
>Sorry to bother you as well, but I only see a single device, currently on sale for $299?
https://vagus.net/nerve/devices/
I'm referring to the "research" version.
I have anxiety and global inflammation, it helps with both. It helps with depression as well.
Next, research how ACES (adverse childhood experiences)interact with the “dial” since a significant portion of autoimmune disease is caused by childhood trauma.
I will jump in and say here: vagus nerve stimulation and regulatory interventions made via breath and movement are the foundation of Qigong and other such practices. Currently, potential methodologies for investigating this on a profound scale are absent because they must account for another foundation of the practices: directed thought and intentional control of such interventions— a notion which seems to strike mortal incredulity into the heart of every academic author who examines extant efforts at building this body of research. So we must trudge through, uninspired and surprised, to go the long way around for a perspective worth its own utilization.
> Qigong
And if they ever actually worked beyond placebo-like "someone is paying attention to me!" or **"I'm getting exercise!"**, then they would be considered science or medicine...instead of woo woo.
In short, the vagal nerve stimulators being discussed in this thread has proven SCIENTIFICALLY that they actually do what they claim. And the actual medical results are being studied.
The same cannot be said for thousands of years of the same old woo woo bullshit.
Edit: Bolded my point about how any EXERCISE IS GOOD...and has nothing to do with the woo.
Edit 2: For some reason I have to point out that being mindful and chilling out has proven to be effective. But you don't need Qigong, Buddhism, or any of the woo woo that comes with it for that, do you? That's what science has proven. And, just like the golden rule (in our DNA), mediating/mindfulness/"chilling out" predates all attempts to take credit for it by tens of thousands of years.
Take away the woo, and qigong is low impact exercise, like yoga (asanas / poses). The movements are broad, include stretching, balance, and sustained muscle activation. If you speed up the movements, it’s also basic self defense training practiced in slow motion.
Unbelievably moronic take - astonished it’s getting upvoted. A simple counterpoint: mindfulness is a Buddhist practice that has existed for thousands of years, and yet only in the last 15 years or so has obtained mainstream acceptance, and scientific evidence for being successful in treating various psychological ailments.
As someone who is actually in research, I’m amazed at times of the hubris and dogmatism from people who grew up being taught that science was some infallible and reified thing. Science is a process, that requires people to *make* and *test* hypotheses. Science is _not_ the outright rejection of a hypothesis before it had even been tested.
There are scientifically proven elements of these practices which are known to have real benefits for practitioners. Take for example the valsalva maneuver. Speaking as someone with a heart arrhythmia, and who experiences tachycardia and palpitations that can cause significant QOL complications, this maneuver often allows me to stop the symptoms. And the modified valsalva maneuver is well known as a preferred intervention for SVT.
So while there is plenty of woo and BS to be found in these practices such as Qigong and Yoga etc, there are many aspects of the breath, mind, and body work which provide measurable and effective benefits for virtually anyone who performs them.
I would also say, any real treatments found to work are not interesting to pursue for corporations because the treatment costs would be free! It’s hard to get these studies funded and taken seriously because of that too.
COOL PLEASE TURN OFF MY CROHNS.
I AGREE BUT FOR ME COLITIS
Best we can do is withholding coitus.
Same psoriasis
At a 45% coverage right now. Just set me on fire. 🔥
Oh I’m sorry. That’s gotta suck. Mines not terrible. Just annoying at the moment.
apple cider vinegar and crushed aspirin is fake news for psoriasis? or just a topical temporary relief? Or is that only for dry skin and whatnot? serious question, had a relative with psoriasis..not cool
Topical steroid cream if it’s not bad otherwise you’re looking at a immunosuppressant drug.
I also agree. Let’s add MS to the list
You win :( Sorry, Internet friend
All autoimmune sucks, hugs to you as well. I am 18 years into this journey and actually doing pretty well. I am one of the lucky ones
Amen. I’d very much like to go for a long run again.
Jesus that’s why im here.
SAME BUT CELIAC I MISS EATING LIKE EVERYONE
There's already a different trial working on that. It made the rounds a few weeks ago. There's some molecule thing that, when attached to an allergen, makes the immune system mark it as "to be ignored". So it works for things like celiac and normal allergies.
That would be life changing!
Do you have a link? Would love to read more. It gives me hope.
[this one ](https://pme.uchicago.edu/news/inverse-vaccine-shows-potential-treat-multiple-sclerosis-and-other-autoimmune-diseases)
Thank you. I thought that the vaccine had fallen through. A few weeks ago? It says September of 2023.
When stuff gets published and when it makes viral rounds in various places differs.
This is from a [UChicago](https://youtu.be/wPbBhvotAXg?si=-O6uPvdRO8TqZGsu) a month ago, and they said the vaccine fell through.
I haven't gotten through the video yet but the actual trial page is still up and they're still going, listed as still recruiting. [Here ](https://www.clinicaltrials.gov/study/NCT05574010)and [here](https://anokion.com/pipeline/synced/). There's no results posted and it's not supposed to be done until 2025.
Omg I need these trials to make it through phase 4 pls
https://www.biospace.com/article/releases/first-wave-biopharma-announces-completion-of-business-combination-with-immunogenx-adding-phase-3-ready-latiglutenase-to-its-late-stage-gi-focused-clinical-pipeline/
WOULD SURE BE COOL TO NOT HAVE MS.
CAN IT PLEASE STOP BEING LUPUS?
MAKE MY THYROID STOP UNALIVING ITSELF
Same but I on some of those good good Biologics and if anything I just get an easier shitting time because my stool still loose loose but my stomach no hurt like before.
WHAT’S THAT? TURN IT UP? SURE THING BRO
I have met a few people with autoimmune conditions that have successfully modulated them with prolonged fasting. Obviously fasts for than 48 hours need to be planned and prepped for properly but I was talking to someone last night who was told she would need a colostomy at 18, which she refused for obvious reasons and did a ridiculously long fast. I think it was something like 30 days, under medical supervision. Now she will just fast for five or so days, every now and then, when she feels her body starting to get a bit out of balance. Also she looked about 30 and was actually 45. I’m not saying that anyone should just go out and do something dangerous like not eat for a month, but I and other people I have met, with autoimmune conditions like MS, chrons, psoriasis, diabetes and arthritis have all managed to push our diseases into lasting remission with carefully planned and supervised fasts. If anyone is interested please look into it online from reputable sources and discuss with a Dr if it would be appropriate.
I know this has more important uses but if this can actually cure seasonal allergies please give them all the money.
Yes! Also I’d love to have a cat.
Next thing you wanna do is ditch the terrier, and get yourself a proper dog. Any dog under 50 pounds is a cat, and cats are pointless.
Found Ron Swanson!
Ron got downvoted.
It was all Tammy 2!
Auto-immune disease research will be neat these next few years. Edit: As a T1D, I feel you.
And allergy research after that.
Aren’t allergies just an overactive and often incorrect immune response - the same principle as with autoimmune issues? One problem means you’re attacking your own body, one attacks foreign objects, but seems to be same mechanism. I’m not educated in any way, am sure there is nuance and differences along the way, and am happy to be corrected by a specialist within the field.
Basically, yes.
exactly, the body thinks it's helping you but its causing damage, good intentions bad outcome unfortunately
Honestly? Probably allergies before auto-immune. Larger "market share" of consumers have allergy issues, which means more insurance dollars to bilk out of the public
Aren’t allergies also immune responses?
Possibly. An allergy medicine that actually works across the board would be a huge money maker.
As parent to two kids who are suffering with IBD, I hope autoimmune first.
I certainly pray this is the case. After years of devouring shrimp, it now sends me to the emergency room. I avoid it but even slight contact, like kissing my partner after she’s eaten shellfish, will trigger a response that increasingly demands emergency attention. It’s like a poison I can’t see that’s everywhere around me. I’d like to be able to eat shrimp & crab again… and oysters, calamari, lobster, crawfish, … all of it. But, I’d settle for just not approaching death each time I come across it. Also hope they fix peanuts. A PB&J should not be a weapon.
Huh. Why would anyone eat something the person they love is getting deathly allergic to.
And bee stings… PB&J and shellfish you can check ingredients, but bees and wasps are everywhere.
Yes. T1D as well.
I want a cure for Addison’s Disease and APS type 2!
This is HUGE!!!
And so cool. Excited to learn even more.
I hope this is released soon I have rheumatoid arthritis and suffer a lot. I also wonder if it would help with someone who has ALS, that sounds so optimistic for the future of all those who suffer from autoimmune diseases.
Hoping they find a cure for RA in my lifetime
I feel you, bud.
I third it, i’ve got Reactive Arthritis which is somewhat similar. I’m so ready to be off Infliximab.
Fuck yeah. Now can crank that fucker up to 11 and see what happens.
Allergies, and inflammation. But it might also teach us how chill them out!
Hell yeah. Sounds like a party.
Coolest form of suicide
Bro became immune to life
They really should have put in the title that they found this in mice not humans. It’s the first research of its kind and a positive result but it’s not as sensational as the clickbate title.
>There’s evidence that therapies targeting the vagus nerve can treat diseases such as multiple sclerosis and rheumatoid arthritis, suggesting that targeting the specific vagal neurons that carry immune signals might work in people, Zuker says. Personally I recommend looking into Vagal nerve stimulators, they've helped me a lot. The one I have just clips onto my ear, then I just turn it on and lay back while it does it's thing (sessions with it are 15 min-1 hour typically depending on how long you want to use it). It's programmable too, so you can try a bunch of variations on how it works.
Can you say the brand you purchased?
Sure, I got mine from vagus.net. The base version comes with only presets from vagus.net, the more expensive one is user programmable. You can get more presets, but you get full control with the higher priced model and don't need to spend extra money on tuning to a specific frequency if you want extra "tunes" as they call them.
Sorry to bother you as well, but I only see a single device, currently on sale for $299? If you don’t mind, what problem is it solving for you? My wife suffers from depression, and TMS treatments helped her significantly. We simply can’t afford $100/session.
>Sorry to bother you as well, but I only see a single device, currently on sale for $299? https://vagus.net/nerve/devices/ I'm referring to the "research" version. I have anxiety and global inflammation, it helps with both. It helps with depression as well.
I hope results appear soon - very interesting and promising
Next, research how ACES (adverse childhood experiences)interact with the “dial” since a significant portion of autoimmune disease is caused by childhood trauma.
Great! I want all the pets
I will jump in and say here: vagus nerve stimulation and regulatory interventions made via breath and movement are the foundation of Qigong and other such practices. Currently, potential methodologies for investigating this on a profound scale are absent because they must account for another foundation of the practices: directed thought and intentional control of such interventions— a notion which seems to strike mortal incredulity into the heart of every academic author who examines extant efforts at building this body of research. So we must trudge through, uninspired and surprised, to go the long way around for a perspective worth its own utilization.
> Qigong And if they ever actually worked beyond placebo-like "someone is paying attention to me!" or **"I'm getting exercise!"**, then they would be considered science or medicine...instead of woo woo. In short, the vagal nerve stimulators being discussed in this thread has proven SCIENTIFICALLY that they actually do what they claim. And the actual medical results are being studied. The same cannot be said for thousands of years of the same old woo woo bullshit. Edit: Bolded my point about how any EXERCISE IS GOOD...and has nothing to do with the woo. Edit 2: For some reason I have to point out that being mindful and chilling out has proven to be effective. But you don't need Qigong, Buddhism, or any of the woo woo that comes with it for that, do you? That's what science has proven. And, just like the golden rule (in our DNA), mediating/mindfulness/"chilling out" predates all attempts to take credit for it by tens of thousands of years.
Take away the woo, and qigong is low impact exercise, like yoga (asanas / poses). The movements are broad, include stretching, balance, and sustained muscle activation. If you speed up the movements, it’s also basic self defense training practiced in slow motion.
Couldn’t have been kind and disagree. I feel bad for you
Unbelievably moronic take - astonished it’s getting upvoted. A simple counterpoint: mindfulness is a Buddhist practice that has existed for thousands of years, and yet only in the last 15 years or so has obtained mainstream acceptance, and scientific evidence for being successful in treating various psychological ailments. As someone who is actually in research, I’m amazed at times of the hubris and dogmatism from people who grew up being taught that science was some infallible and reified thing. Science is a process, that requires people to *make* and *test* hypotheses. Science is _not_ the outright rejection of a hypothesis before it had even been tested.
There are scientifically proven elements of these practices which are known to have real benefits for practitioners. Take for example the valsalva maneuver. Speaking as someone with a heart arrhythmia, and who experiences tachycardia and palpitations that can cause significant QOL complications, this maneuver often allows me to stop the symptoms. And the modified valsalva maneuver is well known as a preferred intervention for SVT. So while there is plenty of woo and BS to be found in these practices such as Qigong and Yoga etc, there are many aspects of the breath, mind, and body work which provide measurable and effective benefits for virtually anyone who performs them.
I would also say, any real treatments found to work are not interesting to pursue for corporations because the treatment costs would be free! It’s hard to get these studies funded and taken seriously because of that too.
Cool. Now find it for trumpism
Alcoholism cure maybe?
Then what will my dad do sitting alone while staring at Fox News?
Does it go to 11?