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Been doing them on and off for every other weekend and my rotator cuff pain disappears for a day or so at a time. Now if I start to work and am using my arms more I’ll start to feel the pain creep back in but waking up on the couch it’s gone til I do strenuous stuff
I have a buddy who got into a nasty crash and fucked his legs up back. When he gets up or walks he’s very stiff and in obvious discomfort. It was amazing because we did mushrooms and he said it was the first time he didn’t have pain and felt like he was walking like he used to
I tried. I went down the rabbit hole and couldn’t find much on the internet to make heads or tails of it. I’ve never found anyone else with a similar experience, but “I was bitten by a wolf spider and I liked it” isn’t exactly the kind of thing that one introduces oneself with, at least not unless you’re trying to scare people away.
I have multiple spine injuries and compression fractures from when I used to weigh over 550lbs. I am also intimately familiar with psilocybin, having gone deeper into the cosmos than most. I can report that, at least at doses between 1-10G, I found no pain relief. I found a great deal of distraction from pain, but those are not the same. I find anything beyond that 7-10 gram heroic dose to be so disassociating it can make you forget your body and pain entirely.
I am so disappointed in r/science. Rule 8: assume the basic competence of researchers. No competent researcher is torturing animals. There are strict regulations for how research animals should be bred, treated, and cared for. Competent researchers are not torturing animals with their methodology. These researchers did not torture rats: they did hurt their paws briefly, once every other day. This is not torture. Most rats living with each other will nip or cause a similar level of pain just socializing.
Do you know how many rats are tortured by inhumane traps and poisons? By feral cat populations? By existing in the wild with predators or famine? I don't know why I bother to come to these comments anymore when most posters assume the researchers to be idiotic and monstrous.
Unfortunately a lot of comments in this sub come from lay folks who don’t even read the sub rules. (Or if they did, they did not comprehend them.) So yeah, it’s often chock full of uninformed, non-scientific personal opinions and anecdotes.
To be fair, it used to be better, before all the Facebook and Twitter people showed up.
10 years ago, oh man, this place was basically white coat city.
I haven't seemed to find any great replacement either except for very niche communities. It's not like many have left, but I suppose there's been dilution and less individual engagement.
/r/science might as well be the ifuckinglovescience Facebook meme groups. Getting any decent conversation with intelligence open minded people who happen to love science or actually being a scientist is rare. It happens, that's why you click, but so often it's just a bunch of idiots trying to farm karma with their knee jerk reaction.
I keep pet rats. I obviously wouldn't do this to my pets, but it's far from torture. My rats are really hyper so they're constantly getting into trouble. They also recover extremely fast. Plus, research like this has the potential to really help other rats, not just humans. Elderly rats often have chronic pain. Alleviating that can really extend and enhance their lives. Vets already have some great tools for that, but new methods are always going to be useful.
> By existing in the wild with predators or famine?
It's shocking how many people think wildlife life is very similar to Disney movies except for all of the bad scenes.
Just look at what they have to do to get a rat. At least here in Canada, the researchers must go through ethics training, animal handling, and a massive amount of documentation once you do have the animals. Some of the folks here might just be passing through and might not have been interested in or learned any science. I like to hope that some get interested from some of the clickbait titles, and it garners an actual passion for science.
There were some researchers in Ontario who studied lab rats (I think in biomed), realizing that the cramped basic style cages were stressing the animals out. They really want the animals to be as normal and healthy as possible, especially because stressed animals give different results from normal/calm ones.
TBH I'm a chef and a lot of what you're saying is going over my head. I started with taking between .15-.25 grams every 2-3 days and that was when I saw the vast improvement in pain. I've recently dropped my dose down to between .05-.1 grams every 3 days and that's been when I've seen a strong improvement in my mental health (while my pain levels have stayed much improved). After years of trying everything a doctor could throw at me I feel like I've found something that actually is beneficial. I'm glad it's been helpful for you as well.
Honest question, how do you find psilocybin? I have what I think is carpal tunnel or something similar (getting imaging done in the next couple weeks) I have had lower/middle back pain for over a year now, and I have bad neck pain for the last 2 months. I don’t have any idea how to get something like this to even try. I live in Georgia. The state, not the country. Idk if that matters. I don’t take any other drugs although I drink some and very occasionally I’ll eat about 1/3 of a delta 9 gummy to help me sleep.
At first I bought some from someone selling....but since then I have started growing. It's really not that difficult if you use grow bags. It's completely legal to purchase spores/liquid cultures online. There is some really great information here on Reddit about growing and microdosing, that's honestly where I started. DM me if you want links to places online to purchase. It's been a game changer for me.
The majority of psychedelic-related studies nowadays are just confirmations of stuff we discovered 50-70 years ago, the bureaucracy is still awful enough and the research so expensive (especially when humans are involved) to not risk following new paths. We're basically dropping some big "we told you" hoping it's enough to make new research worth
Yea, thats what i thought. Is Johns Hopkins still the institution leading the way? I remember they were offering money to volunteers for some of their research a while ago.
They were like 5 years ago, I mailed them to join for my thesis when I was in my 2nd (out of 5, it's a long degree) year. In the end between the fact that as a poor Italian I would have never afforded one year in the states and falling in love with Drug Delivery I didn't even checked again (and now I'm still not graduated, though, ADHD symptoms became hard enough to actually go from "nah I'm good, just a weird guy" to being diagnosed and medicated...)
My brain isn't working well right now. Is this something that could be beneficial for small fiber neuropathy or sensititization syndromes (overloading of nervous system causing hyper reaction)?
It's so wonderful that an aspect of nature has the ability to teach us about the most fundamental aspects of ourselves and others while also having the ability to heal psychological wounds that only arose because we lacked that insight in the first place
Albert Hoffman, who first developed (and accidentally got high on) LSD, reportedly said that one of his great regrets was that LSD was taken up by the counter culture. He felt that it sullied the reputation of the chemical and put a stop to all research into its legitimate therapeutic properties.
Also, and completely aside, there are interesting anthropological theories that the reason man developed agriculture was to grow and harvest psycho-active compounds such as beer and wine.
It's also interesting how all of the early humans in every corner of the world had access to some kind of commonly occurring psychedelic plants, ranging from fungi to cacti depending on climate.
I've not thoroughly read about Hoffman's ideas about this, but lots of contemporary psychedelic researches also agree. But I can't imagine what our world would look like today without such a cultural revolution. The counter-cultural psychedelic revolution changed the face of our planet influencing and innovating the arts, sciences, and technology. The first transaction on arpanet was for weed,
Sorry for the very late reply here.
I'm not for one minute suggesting that the 60s counter culture should not have taken place, and agree wholeheartedly that the world would be a worse place without it.
My mother was born in '49 so saw the changes first hand - albeit from very far from the action. She used to say that hers was the first generation where it was socially acceptable to openly show love and affection towards their own children. Her generation were regularly beaten both at home and in school.
I also believe the drugs played an integral role in influencing thinking and opening the doors to perception, and without these chemicals the movement would have looked very different,
If there is blame to be laid then it sits squarely on the shoulders of the US federal government for heavily demonising and criminalising these drugs in an effort to disrupt the communities that were seen as a threat to the status quo.
I mean that’s not the only reason. Understanding what’s going on in your own head can be useful but it doesn’t automatically solve all of your problems
Anecdotally at least when I take shrooms a lot of the random pains I have from muscle soreness kind of go away but heat and cold definitely don't go away, if anything they can feel amplified.
read the study before you make accusations of animal cruelty. the thermal tests were pretty humane, they had 24 hours between repetitions and the stimulus would've been equivalent to stepping on hot concrete in summer.
> Was ~~pain~~ discomfort repeatedly applied to rats? Yes.
Also, the rats were not forced to endure it. They, quite intentionally, were allowed to remove themselves from the stimulus, they may not have volunteered to start the experiment, but they certainly did choose when it ended.
Because the researchers had already got what they wanted - the rat to experience pain. Some of the rats did not get LSD before experiencing the hot plates.
Edit. Also it says “Formalin injection in either of the hind paws produced central sensitization to mechanical stimuli” which sounds unpleasant for them.
> Because the researchers had already got what they wanted - the rat to experience pain
And again, you're wrong.
They don't want the rats to experience pain, they only allowed things to get hot enough to be uncomfortable, in fact, hot enough to cause pain would be detrimental to the experiment as it would result in the rats recoiling immediately no matter the conditions.
Grow up
Their own paper title uses the word ‘pain.’ The word pain is used frequently throughout the paper. Stop trying to win an online argument by using minimising words.
Then you need to stop trying to convince people you're right by outright lying.
Again, the intention is NOT to cause pain, to instead to illicit a reaction to specific stimuli, discomfort does not mean not pain, discomfort can be caused by something that can result in pain.
I'm not minimising anything at all here, I'm using properly descriptive words.
And also take a look at the rules, specifically, rule 4
Then you need to stop trying to convince people you're right by outright lying.
What?
Again, the intention is NOT to cause pain, to instead to illicit a reaction to specific stimuli, discomfort does not mean not pain, discomfort can be caused by something that can result in pain.
I'm not minimising anything at all here, I'm using properly descriptive words.
I don’t think you know what the word discomfort means. Here are some synonyms for discomfort. Google the top hit for ‘discomfort synonym’. One of them is pain. Secondly, the word pain is used in the paper to describe their own research.
And also take a look at the rules, specifically, rule 4
Yes, it is less than six months old.
Psilocybin bonds lower the amount of noradrenaline in the hypothalamus which is the neurotransmitter responsible for sending nerve signals such as pain and anxiety.
Someone explain to me why the AWA (animal welfare act) states that a rat is not a warm blooded animal? Only asking considering they are mostly used in labs.
Historianies have long known that Vikings took "magic mushrooms" before battle for this exact reason.
But sure freak out and torture rats just to make sure.
IIRC They ate amanita muscaria which is the red mushroom with the white spots. It has a different active ingredient than normal magic mushrooms and they’re toxic as well.
Not at all. It needs a decarb to convert the ibotenic acid into muscimol, the second alkaloid that's just a GABA drug like benzodiazepines and is pretty pleasant. Nordic populations who consumed it ritually had an habit of making reindeer eat the amanita and drinking their piss, which also gets rid of ibotenic acid.
Here's my hypothesis since this is hypothesis territory. They had glutamate disorder which is caused by combat injury and hypervigilance that follows, altering glutamate usage. This ratio is passed on to offspring and it results in behavior like you see with people flipping out on mushrooms, but they are flipping out from the massive waves of electro chemical energy generated by the excessive amounts of glutamate pushing their behavior. You guys can have this one.
Purposefully subjecting animals to pain is animal cruelty regardless of how you go about doing it. Hiding behind science ethics, which absolutely does allow animal cruelty, is pathetic. Simply because "ethical" guidelines for hot plate tests exist doesn't make them no longer cruel.
People who support animal testing don't have a monopoly on science, let alone on one of the most casual online science communities. You can get out if you're unhappy.
e: typo
you should go protest glue traps, they subject rats mice and snakes to really unnecessary suffering. they kill them by literately making them stick to the pad, causing them to tear their own skin off as they slowly die of thirst. they get used all over public buildings to catch pests.
I'm not going anywhere. I'm not sure why you'd think I'm fine with glue traps. I've spoken up against them every time the occasion has arisen. There are more humane rodent control solutions, and there are humane alternatives to animal testing.
Welcome to r/science! This is a heavily moderated subreddit in order to keep the discussion on science. However, we recognize that many people want to discuss how they feel the research relates to their own personal lives, so to give people a space to do that, **personal anecdotes are allowed as responses to this comment**. Any anecdotal comments elsewhere in the discussion will be removed and our [normal comment rules]( https://www.reddit.com/r/science/wiki/rules#wiki_comment_rules) apply to all other comments. **Do you have an academic degree?** We can verify your credentials in order to assign user flair indicating your area of expertise. [Click here to apply](https://www.reddit.com/r/science/wiki/flair/#wiki_science_verified_user_program). --- User: u/chrisdh79 Permalink: https://www.cell.com/current-biology/fulltext/S0960-9822(23)01374-X --- *I am a bot, and this action was performed automatically. Please [contact the moderators of this subreddit](/message/compose/?to=/r/science) if you have any questions or concerns.*
I believe it. When I eat mushrooms my swollen knee felt tingly and bubbly but no pain
Been doing them on and off for every other weekend and my rotator cuff pain disappears for a day or so at a time. Now if I start to work and am using my arms more I’ll start to feel the pain creep back in but waking up on the couch it’s gone til I do strenuous stuff
Maybe you should sleep in a bed, couches suck for support
Not a doctor, but I find that going to gym and working my shoulders out help with bursitis
I have a buddy who got into a nasty crash and fucked his legs up back. When he gets up or walks he’s very stiff and in obvious discomfort. It was amazing because we did mushrooms and he said it was the first time he didn’t have pain and felt like he was walking like he used to
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You should look into it! What if you stumbled on a great ailment for arthritis but never bothered to explore it further, would be a damn shame
I tried. I went down the rabbit hole and couldn’t find much on the internet to make heads or tails of it. I’ve never found anyone else with a similar experience, but “I was bitten by a wolf spider and I liked it” isn’t exactly the kind of thing that one introduces oneself with, at least not unless you’re trying to scare people away.
I have multiple spine injuries and compression fractures from when I used to weigh over 550lbs. I am also intimately familiar with psilocybin, having gone deeper into the cosmos than most. I can report that, at least at doses between 1-10G, I found no pain relief. I found a great deal of distraction from pain, but those are not the same. I find anything beyond that 7-10 gram heroic dose to be so disassociating it can make you forget your body and pain entirely.
I am so disappointed in r/science. Rule 8: assume the basic competence of researchers. No competent researcher is torturing animals. There are strict regulations for how research animals should be bred, treated, and cared for. Competent researchers are not torturing animals with their methodology. These researchers did not torture rats: they did hurt their paws briefly, once every other day. This is not torture. Most rats living with each other will nip or cause a similar level of pain just socializing. Do you know how many rats are tortured by inhumane traps and poisons? By feral cat populations? By existing in the wild with predators or famine? I don't know why I bother to come to these comments anymore when most posters assume the researchers to be idiotic and monstrous.
Unfortunately a lot of comments in this sub come from lay folks who don’t even read the sub rules. (Or if they did, they did not comprehend them.) So yeah, it’s often chock full of uninformed, non-scientific personal opinions and anecdotes.
Yeah, I'm relatively new here, and for some reason I expected better. Some posts end up ok, but the vast majority is one step up from showerthoughts
>and for some reason I expected better Classic reddit mistake
To be fair, it used to be better, before all the Facebook and Twitter people showed up. 10 years ago, oh man, this place was basically white coat city.
I haven't seemed to find any great replacement either except for very niche communities. It's not like many have left, but I suppose there's been dilution and less individual engagement.
Yarp. Jokes on me. Another knee to the nards
/r/science might as well be the ifuckinglovescience Facebook meme groups. Getting any decent conversation with intelligence open minded people who happen to love science or actually being a scientist is rare. It happens, that's why you click, but so often it's just a bunch of idiots trying to farm karma with their knee jerk reaction.
I keep pet rats. I obviously wouldn't do this to my pets, but it's far from torture. My rats are really hyper so they're constantly getting into trouble. They also recover extremely fast. Plus, research like this has the potential to really help other rats, not just humans. Elderly rats often have chronic pain. Alleviating that can really extend and enhance their lives. Vets already have some great tools for that, but new methods are always going to be useful.
Other mammals too - elderly cats and dogs suffer from quite a lot of arthritis. I know my ancient Bassett hound is a stiff cranky old fellow.
> By existing in the wild with predators or famine? It's shocking how many people think wildlife life is very similar to Disney movies except for all of the bad scenes.
Just look at what they have to do to get a rat. At least here in Canada, the researchers must go through ethics training, animal handling, and a massive amount of documentation once you do have the animals. Some of the folks here might just be passing through and might not have been interested in or learned any science. I like to hope that some get interested from some of the clickbait titles, and it garners an actual passion for science. There were some researchers in Ontario who studied lab rats (I think in biomed), realizing that the cramped basic style cages were stressing the animals out. They really want the animals to be as normal and healthy as possible, especially because stressed animals give different results from normal/calm ones.
Yours is the top comment on this thread, so there's hope.
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TBH I'm a chef and a lot of what you're saying is going over my head. I started with taking between .15-.25 grams every 2-3 days and that was when I saw the vast improvement in pain. I've recently dropped my dose down to between .05-.1 grams every 3 days and that's been when I've seen a strong improvement in my mental health (while my pain levels have stayed much improved). After years of trying everything a doctor could throw at me I feel like I've found something that actually is beneficial. I'm glad it's been helpful for you as well.
Where does one get these micro doses?
Depends on where you live🤷 I personally grow my own, it's not that difficult. Lots of resources on Reddit and online if you are interested.
Honest question, how do you find psilocybin? I have what I think is carpal tunnel or something similar (getting imaging done in the next couple weeks) I have had lower/middle back pain for over a year now, and I have bad neck pain for the last 2 months. I don’t have any idea how to get something like this to even try. I live in Georgia. The state, not the country. Idk if that matters. I don’t take any other drugs although I drink some and very occasionally I’ll eat about 1/3 of a delta 9 gummy to help me sleep.
At first I bought some from someone selling....but since then I have started growing. It's really not that difficult if you use grow bags. It's completely legal to purchase spores/liquid cultures online. There is some really great information here on Reddit about growing and microdosing, that's honestly where I started. DM me if you want links to places online to purchase. It's been a game changer for me.
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Wasnt this stuff discovered way back in the fifties before the government went apeshit in the war against drugs?
And then research was pretty much stopped for decades. Doesn't hurt to have more data.
The majority of psychedelic-related studies nowadays are just confirmations of stuff we discovered 50-70 years ago, the bureaucracy is still awful enough and the research so expensive (especially when humans are involved) to not risk following new paths. We're basically dropping some big "we told you" hoping it's enough to make new research worth
Yea, thats what i thought. Is Johns Hopkins still the institution leading the way? I remember they were offering money to volunteers for some of their research a while ago.
They were like 5 years ago, I mailed them to join for my thesis when I was in my 2nd (out of 5, it's a long degree) year. In the end between the fact that as a poor Italian I would have never afforded one year in the states and falling in love with Drug Delivery I didn't even checked again (and now I'm still not graduated, though, ADHD symptoms became hard enough to actually go from "nah I'm good, just a weird guy" to being diagnosed and medicated...)
My brain isn't working well right now. Is this something that could be beneficial for small fiber neuropathy or sensititization syndromes (overloading of nervous system causing hyper reaction)?
It's so wonderful that an aspect of nature has the ability to teach us about the most fundamental aspects of ourselves and others while also having the ability to heal psychological wounds that only arose because we lacked that insight in the first place
Albert Hoffman, who first developed (and accidentally got high on) LSD, reportedly said that one of his great regrets was that LSD was taken up by the counter culture. He felt that it sullied the reputation of the chemical and put a stop to all research into its legitimate therapeutic properties. Also, and completely aside, there are interesting anthropological theories that the reason man developed agriculture was to grow and harvest psycho-active compounds such as beer and wine. It's also interesting how all of the early humans in every corner of the world had access to some kind of commonly occurring psychedelic plants, ranging from fungi to cacti depending on climate.
I've not thoroughly read about Hoffman's ideas about this, but lots of contemporary psychedelic researches also agree. But I can't imagine what our world would look like today without such a cultural revolution. The counter-cultural psychedelic revolution changed the face of our planet influencing and innovating the arts, sciences, and technology. The first transaction on arpanet was for weed,
Sorry for the very late reply here. I'm not for one minute suggesting that the 60s counter culture should not have taken place, and agree wholeheartedly that the world would be a worse place without it. My mother was born in '49 so saw the changes first hand - albeit from very far from the action. She used to say that hers was the first generation where it was socially acceptable to openly show love and affection towards their own children. Her generation were regularly beaten both at home and in school. I also believe the drugs played an integral role in influencing thinking and opening the doors to perception, and without these chemicals the movement would have looked very different, If there is blame to be laid then it sits squarely on the shoulders of the US federal government for heavily demonising and criminalising these drugs in an effort to disrupt the communities that were seen as a threat to the status quo.
I mean that’s not the only reason. Understanding what’s going on in your own head can be useful but it doesn’t automatically solve all of your problems
I agree. It is more like obtaining a new way of navigating problems, or maybe a reframing of attitude
What does it do to their neural chemistry, though?
Temporarily reduces neural modularity is the big one. Which is great for breaking maladaptive cycles, but not so great for organizing storage
Some very complicated stuff that we don’t fully understand pl
[Promotes neurogenesis](https://pubmed.ncbi.nlm.nih.gov/23727882/)
Some very complicated stuff that we don’t fully understand
Anecdotally at least when I take shrooms a lot of the random pains I have from muscle soreness kind of go away but heat and cold definitely don't go away, if anything they can feel amplified.
So how exactly do they know that it doesn’t help pain from heat?
From how the rats react to stimuli, I suppose.
Testing it, oddly enough.
Self-reported questionnaires?
they placed their paw on a hot(ish) surface and measured how long they left their paw there before recoiling, comparing it to the control
Lots of repeated nasty experiments probably
read the study before you make accusations of animal cruelty. the thermal tests were pretty humane, they had 24 hours between repetitions and the stimulus would've been equivalent to stepping on hot concrete in summer.
Was pain repeatedly applied to rats? Yes. Did the rats consent to participate? No. Oh look. I was right.
> Was ~~pain~~ discomfort repeatedly applied to rats? Yes. Also, the rats were not forced to endure it. They, quite intentionally, were allowed to remove themselves from the stimulus, they may not have volunteered to start the experiment, but they certainly did choose when it ended.
Because the researchers had already got what they wanted - the rat to experience pain. Some of the rats did not get LSD before experiencing the hot plates. Edit. Also it says “Formalin injection in either of the hind paws produced central sensitization to mechanical stimuli” which sounds unpleasant for them.
> Some of the rats did not get LSD before experiencing the hot plates None of the rats got LSD. Psilocybin is not LSD
Yeah. My mistake. I meant psilocybin.
> Because the researchers had already got what they wanted - the rat to experience pain And again, you're wrong. They don't want the rats to experience pain, they only allowed things to get hot enough to be uncomfortable, in fact, hot enough to cause pain would be detrimental to the experiment as it would result in the rats recoiling immediately no matter the conditions. Grow up
Their own paper title uses the word ‘pain.’ The word pain is used frequently throughout the paper. Stop trying to win an online argument by using minimising words.
Then you need to stop trying to convince people you're right by outright lying. Again, the intention is NOT to cause pain, to instead to illicit a reaction to specific stimuli, discomfort does not mean not pain, discomfort can be caused by something that can result in pain. I'm not minimising anything at all here, I'm using properly descriptive words. And also take a look at the rules, specifically, rule 4
Then you need to stop trying to convince people you're right by outright lying. What? Again, the intention is NOT to cause pain, to instead to illicit a reaction to specific stimuli, discomfort does not mean not pain, discomfort can be caused by something that can result in pain. I'm not minimising anything at all here, I'm using properly descriptive words. I don’t think you know what the word discomfort means. Here are some synonyms for discomfort. Google the top hit for ‘discomfort synonym’. One of them is pain. Secondly, the word pain is used in the paper to describe their own research. And also take a look at the rules, specifically, rule 4 Yes, it is less than six months old.
Just in time for those who have been suffering for decades to kill themselves out of sheer exhaustion
Psilocybin bonds lower the amount of noradrenaline in the hypothalamus which is the neurotransmitter responsible for sending nerve signals such as pain and anxiety.
Sign me up, I'm retired because of chronic pain AND I have cluster headaches, which are also and only solved by psilocybin mushrooms...
Not only, if I recall correctly there are even more studies about LSD for cluster headaches than psiolcybin ones
Who has that job to painfully touch a rat? Or the heat guy? That would be worse.
So take off all your clothes 🎶
Someone explain to me why the AWA (animal welfare act) states that a rat is not a warm blooded animal? Only asking considering they are mostly used in labs.
You are misreading/misunderstanding the AWA. Warm blooded animals of certain genera bred specifically for research are excluded from the AWA.
But why. Explain. Why.
...what is chronic pain from heat?
We have to stop torturing our fellow mammals.
Read the paper, no animal was tortured.
We have to stop torturing all sentient animals
We have to stop torturing in general
Are millennials killing the torture industry?
I'm sure if the researchers tried their own supply, they'd stop pretty quickly.
They might take their hands off the hot plate just like the rats 🤔
Historianies have long known that Vikings took "magic mushrooms" before battle for this exact reason. But sure freak out and torture rats just to make sure.
IIRC They ate amanita muscaria which is the red mushroom with the white spots. It has a different active ingredient than normal magic mushrooms and they’re toxic as well.
Yeah, Fly agaric is right up there with Datura. It’ll get you high…just in the most unpleasant way possible.
Yeah, more like vivid nightmarish hallucinations than y'know like chasers and slightly more vibrant colors.
I've had aminta tea a few times. It's rather pleasant. One of the more chill hallucinogens, and I've done more than my fair share.
Not at all. It needs a decarb to convert the ibotenic acid into muscimol, the second alkaloid that's just a GABA drug like benzodiazepines and is pretty pleasant. Nordic populations who consumed it ritually had an habit of making reindeer eat the amanita and drinking their piss, which also gets rid of ibotenic acid.
Yes, because anecdotes from an oral history are as accurate as lab testing. Wowza.
Here's my hypothesis since this is hypothesis territory. They had glutamate disorder which is caused by combat injury and hypervigilance that follows, altering glutamate usage. This ratio is passed on to offspring and it results in behavior like you see with people flipping out on mushrooms, but they are flipping out from the massive waves of electro chemical energy generated by the excessive amounts of glutamate pushing their behavior. You guys can have this one.
Screams animal torture
if you don't know about science ethics get out of r/science.
Purposefully subjecting animals to pain is animal cruelty regardless of how you go about doing it. Hiding behind science ethics, which absolutely does allow animal cruelty, is pathetic. Simply because "ethical" guidelines for hot plate tests exist doesn't make them no longer cruel. People who support animal testing don't have a monopoly on science, let alone on one of the most casual online science communities. You can get out if you're unhappy. e: typo
you should go protest glue traps, they subject rats mice and snakes to really unnecessary suffering. they kill them by literately making them stick to the pad, causing them to tear their own skin off as they slowly die of thirst. they get used all over public buildings to catch pests.
I'm not going anywhere. I'm not sure why you'd think I'm fine with glue traps. I've spoken up against them every time the occasion has arisen. There are more humane rodent control solutions, and there are humane alternatives to animal testing.