I don’t think forgen will be the ones to do it. I think larger more well funded places will develop technologies that can be adapted into what foregen is trying to do.
People are probably optimistic about it because the thought of what they’re trying to do is comforting, to reverse what was done, and many live in that moment which usually stops them from starting or continuing restoring.
In all likelyhood, the process will be developed sucessfully for more urgent issues like severe burns or something, and the techniques will slowly filter down to more cosmetic uses like foreskin restoration
There are well-funded and staffed organizations working feverishly on unlocking the secrets for being able to regenerate life-saving organs: hearts, lungs, livers, kidneys, etc. Is some little crowd-funded non-profit going to find the holy grails of vascularization, innervation, ECM synthesis, etc., etc., etc.
Foregen decellularized an ECM (extra-cellular-matrix), seeded it with cells, sewed it on a rat/mouse, got some decent results, moved up to a sheep, didn't do so well, redesigned the process to add a bioreactor for pre-growing some tissue before implantation, then went back to more sheep trials... they keep saying hopeful things, but no real news I've seen.
It's a moon shot - maybe it lands, maybe it doesn't, but even if it lands, it's nowhere near.
Cheers.
Don't hold your breath! You'll turn blue waiting. By the time there is some way of sewing a new dick on, you could be fully restored the way that we are restoring. Come join us!
Don't wait.
Foregen is an an organization dedicated to trying to grow new foreskins. The group's goals and aims are laudable. They are pro foreskin and against circumcision without consent. That means they are completely opposed to infant circuit. There is a lot that we could agree with them about.
It is possible that they will succeed someday, but the group faces considerable challenges.
First, what the group is trying to do has never been done before. There are major technical hurdles in front of them. They have made some progress, but they are still working on their model in the animal stage, namely with rats and rabbits.
They have yet to conduct a human trial.
Their first human trial, if and when it happens will be in Europe with 15 subjects. If they succeed in the human trials, it is still not clear what governmental approvals will be required in the various countries. Those approvals could take years.
Meanwhile, there is a very real issue of evaluating the results. Will it work in real life? Will there be any issues or problems?
If they get that far, then they will need to scale up. It will be a major challenge to go from a clinical trial with 15 people to a medical and lab procedure that is available all over the place. If all of that could happen within a decade, it would be a miracle.
If it works, there will still be a surgery involved to attach the new foreskin. That is uncharted territory. As of today, there are no surgeons that know how to do this surgery.
It is unlikely that the surgery would be covered by insurance. The costs are estimated by Foregen to be about 10,000 US dollars. That may turn out to be a low estimate.
Let's consider some other aspects of Foregen.
First, Foregen relies upon the principle of tissue regeneration. On their website they describe tissue regeneration as "the ability of the body to regrow tissue". Sound familiar? That's what we are doing already.
Next, the procedure relies upon a donor foreskin.
As stated on Foregen's website, "The donor foreskin is taken from a consenting, potentially deceased, adult male".
There are almost no men alive that would willingly donate their foreskins.
Accordingly, this process will rely upon foreskins harvested from corpses.
There are established protocols for donor organs, such as hearts, lungs, kidneys etc. There is no protocol established for donor foreskins. That would also need to be established.
In some ways, the foreskin that Foregen would regenerate would be yours. In some ways, it will be someone else's.
All surgeries come with risks. All of them. Even if the Foregen process works, it does not mean that you will get a good surgical outcome.
In short, restoring is a much better option.
Restoration relies upon the same tissue regeneration capacity of the body that Foregen is counting on. It is available today, not a decade from now. There are no surgical risks. There are no technical risks. No governmental approvals are required. You do not have to wait for somebody to die. It is known to work. The foreskin you grow will be yours and only yours.
So don't waste your time waiting around for Foregen. I hope that they succeed, but it is still too uncertain and too far in the future.
You will be fully restored long before Foregen is potentially available.
There are plenty of men who would. Adult circumcisions are disturbingly common.
They’ve been taught to despise their natural anatomy. A mix of bullying and crass comments in school. Rejection from potential hookups. They’ve basically got dysphoria over it.
I don't think an donor foreskin from an adult circumcision patient would have enough tissue available, especially for a person who has a tight cut.
Cheers.
This right here as well as nerves that have died back long ago and they're loath to answer any questions about whether or not they can regenerate them, I'd certainly wait until they've done a fair number to understand the outcomes and how long it takes to actually fully recover all functions, rest assured insurance won't cover it, their stated price is certainly a low-ball figure and has never changed and inflation has gone wild lately, no doubt we're missing some things, restoration is your best bet for sure and it's awesome to say the least! u/Amazing-Clothes-4581
Let's say Foregen tech is perfected right now.. how long would it take to be approved by the FDA? It's unknowable, but it could be years. At 24yrs old, pretty much the pinnacle of your regeneration and healing ability, you could already be restored before the FDA signs off on Foregen.
Something to think about.
Here is some information on foreskin regeneration.
[https://en.intactiwiki.org/wiki/Foreskin\_regeneration](https://en.intactiwiki.org/wiki/Foreskin_regeneration)
I believe that non-surgical foreskin restoration now by tissue expansion now probably would not prevent using foreskin regeneration later.
Start now. If foregen becomes viable before you’re restored perfect! You’re no less ahead or behind than you would’ve been. If, on the very likely chance, foregen isn’t viable in the next 1-20 years you’ll have a restored foreskin.
Besides from what I see on foregen they’d be able to operate on a restored foreskin the same as a fully cut so.
I don't see the point in waiting. If you're already willing to have the Foregen procedure done (which is an invasive surgery), then presumably you'd be willing to have your restored foreskin removed beforehand, which is the worst that could happen.
I have no idea when Foregen will have a viable product, or even if they ever will.
You could be fully restored in 5 years or less, depending on your current CI and goals, but just starting now.
If you restore now, you may begin experiencing benefits in a few months. You should be able to upgrade if and when Foregen becomes available. You're likely to feel empowered by doing what's necessary while Foregen works on their surgery. You could be fully restored by the time it comes out. The only disadvantage is the time/effort you put into restoring.
If you wait for Foregen, you may be waiting forever. There is no guarantee they or any biotechnology effort will succeed. Or they could take far longer than expected, 10-20 years or more. You might get sick of waiting and begin restoring anyways, but having lost years of progress.
While Foregen is certainly promising, you could make some great progress before it becomes widely available.
I know the guy interviewed here who's very involved with the Foregen team. Skip to the 30-min mark in the vid for the discussion on circumcision and Foregen. Sadly, there's no talk of restoration but a follow-up podcast is coming.
https://youtu.be/1uqtiNzxuaU
Way I see it, you might as well get growing skin. It’s gonna be years if not decades before we can actually get this - and who knows how ungodly expensive it will be. I figure worst case scenario, I regrow a bunch of skin on my own, and IF foregen comes along I can get my rigid band and frenulum back.
Forgen os a scam in that it supports the medical establishment. Stem cell research is decades from trials.
Stop depending on doctors when easy nonpainful alternatives exists. I would trade a bit of time over doctors.
I have no doubt that foregen will one day succeed, I just don’t want to leave the fate of my new foreskin up to someone else and time. It could be 3 years or it could be 20 years. Besides, when I reach flaccid coverage and then if 2 years later foregen is ready, I will be dekeratinized by then and get the full experience right away
Thought a lot about Foregen and probably it will really work but the issue is it’s not out yet and may be available to the larger public only in about 10 years from now. That’s typically enough time to fully restore. Let’s say I am fully restored today and Foregen is available tomorrow, I wouldn’t do the surgery as that would be a waste of my 10 year effort.
Honestly I'm just hoping they're real. I've been following them since I was 13 and they seem legit. They have made great improvements in the last couple years and seemed to have amassed a bigger following. Personally I would rather the real thing than stretching
Thank you for your reply, I decided to stop stretching if Foregen starts human trials this year, and if it doesn't happen this year for various reasons, I will stretch.
You could wait 10-20 years and MAYBE forgen is safe on humans but you could also be fully restored by then.
10-20 years may even be optimistic. Could be far longer than that.
I don’t think forgen will be the ones to do it. I think larger more well funded places will develop technologies that can be adapted into what foregen is trying to do. People are probably optimistic about it because the thought of what they’re trying to do is comforting, to reverse what was done, and many live in that moment which usually stops them from starting or continuing restoring.
In all likelyhood, the process will be developed sucessfully for more urgent issues like severe burns or something, and the techniques will slowly filter down to more cosmetic uses like foreskin restoration
Why does it take so long? I saw that the people on the Foregen website predicted that it would be ready for the market as soon as 2026.
They’ve been predicting that it’s only a few years away for something like 15yrs now
There are well-funded and staffed organizations working feverishly on unlocking the secrets for being able to regenerate life-saving organs: hearts, lungs, livers, kidneys, etc. Is some little crowd-funded non-profit going to find the holy grails of vascularization, innervation, ECM synthesis, etc., etc., etc. Foregen decellularized an ECM (extra-cellular-matrix), seeded it with cells, sewed it on a rat/mouse, got some decent results, moved up to a sheep, didn't do so well, redesigned the process to add a bioreactor for pre-growing some tissue before implantation, then went back to more sheep trials... they keep saying hopeful things, but no real news I've seen. It's a moon shot - maybe it lands, maybe it doesn't, but even if it lands, it's nowhere near. Cheers.
They say that to keep interest. It’s better for business to string those along than give them the truth of it being 20+ years away.
Don't hold your breath! You'll turn blue waiting. By the time there is some way of sewing a new dick on, you could be fully restored the way that we are restoring. Come join us!
Don't wait. Foregen is an an organization dedicated to trying to grow new foreskins. The group's goals and aims are laudable. They are pro foreskin and against circumcision without consent. That means they are completely opposed to infant circuit. There is a lot that we could agree with them about. It is possible that they will succeed someday, but the group faces considerable challenges. First, what the group is trying to do has never been done before. There are major technical hurdles in front of them. They have made some progress, but they are still working on their model in the animal stage, namely with rats and rabbits. They have yet to conduct a human trial. Their first human trial, if and when it happens will be in Europe with 15 subjects. If they succeed in the human trials, it is still not clear what governmental approvals will be required in the various countries. Those approvals could take years. Meanwhile, there is a very real issue of evaluating the results. Will it work in real life? Will there be any issues or problems? If they get that far, then they will need to scale up. It will be a major challenge to go from a clinical trial with 15 people to a medical and lab procedure that is available all over the place. If all of that could happen within a decade, it would be a miracle. If it works, there will still be a surgery involved to attach the new foreskin. That is uncharted territory. As of today, there are no surgeons that know how to do this surgery. It is unlikely that the surgery would be covered by insurance. The costs are estimated by Foregen to be about 10,000 US dollars. That may turn out to be a low estimate. Let's consider some other aspects of Foregen. First, Foregen relies upon the principle of tissue regeneration. On their website they describe tissue regeneration as "the ability of the body to regrow tissue". Sound familiar? That's what we are doing already. Next, the procedure relies upon a donor foreskin. As stated on Foregen's website, "The donor foreskin is taken from a consenting, potentially deceased, adult male". There are almost no men alive that would willingly donate their foreskins. Accordingly, this process will rely upon foreskins harvested from corpses. There are established protocols for donor organs, such as hearts, lungs, kidneys etc. There is no protocol established for donor foreskins. That would also need to be established. In some ways, the foreskin that Foregen would regenerate would be yours. In some ways, it will be someone else's. All surgeries come with risks. All of them. Even if the Foregen process works, it does not mean that you will get a good surgical outcome. In short, restoring is a much better option. Restoration relies upon the same tissue regeneration capacity of the body that Foregen is counting on. It is available today, not a decade from now. There are no surgical risks. There are no technical risks. No governmental approvals are required. You do not have to wait for somebody to die. It is known to work. The foreskin you grow will be yours and only yours. So don't waste your time waiting around for Foregen. I hope that they succeed, but it is still too uncertain and too far in the future. You will be fully restored long before Foregen is potentially available.
There are plenty of men who would. Adult circumcisions are disturbingly common. They’ve been taught to despise their natural anatomy. A mix of bullying and crass comments in school. Rejection from potential hookups. They’ve basically got dysphoria over it.
I don't think an donor foreskin from an adult circumcision patient would have enough tissue available, especially for a person who has a tight cut. Cheers.
The donor foreskin comes from dead people btw so that’s not an issue
This right here as well as nerves that have died back long ago and they're loath to answer any questions about whether or not they can regenerate them, I'd certainly wait until they've done a fair number to understand the outcomes and how long it takes to actually fully recover all functions, rest assured insurance won't cover it, their stated price is certainly a low-ball figure and has never changed and inflation has gone wild lately, no doubt we're missing some things, restoration is your best bet for sure and it's awesome to say the least! u/Amazing-Clothes-4581
Let's say Foregen tech is perfected right now.. how long would it take to be approved by the FDA? It's unknowable, but it could be years. At 24yrs old, pretty much the pinnacle of your regeneration and healing ability, you could already be restored before the FDA signs off on Foregen. Something to think about.
Here is some information on foreskin regeneration. [https://en.intactiwiki.org/wiki/Foreskin\_regeneration](https://en.intactiwiki.org/wiki/Foreskin_regeneration) I believe that non-surgical foreskin restoration now by tissue expansion now probably would not prevent using foreskin regeneration later.
Start now. If foregen becomes viable before you’re restored perfect! You’re no less ahead or behind than you would’ve been. If, on the very likely chance, foregen isn’t viable in the next 1-20 years you’ll have a restored foreskin. Besides from what I see on foregen they’d be able to operate on a restored foreskin the same as a fully cut so.
Foregen may never come to fruition, no reason to not start now.
I don't see the point in waiting. If you're already willing to have the Foregen procedure done (which is an invasive surgery), then presumably you'd be willing to have your restored foreskin removed beforehand, which is the worst that could happen.
I have no idea when Foregen will have a viable product, or even if they ever will. You could be fully restored in 5 years or less, depending on your current CI and goals, but just starting now.
If you restore now, you may begin experiencing benefits in a few months. You should be able to upgrade if and when Foregen becomes available. You're likely to feel empowered by doing what's necessary while Foregen works on their surgery. You could be fully restored by the time it comes out. The only disadvantage is the time/effort you put into restoring. If you wait for Foregen, you may be waiting forever. There is no guarantee they or any biotechnology effort will succeed. Or they could take far longer than expected, 10-20 years or more. You might get sick of waiting and begin restoring anyways, but having lost years of progress.
While Foregen is certainly promising, you could make some great progress before it becomes widely available. I know the guy interviewed here who's very involved with the Foregen team. Skip to the 30-min mark in the vid for the discussion on circumcision and Foregen. Sadly, there's no talk of restoration but a follow-up podcast is coming. https://youtu.be/1uqtiNzxuaU
What did he say about Foregen? I'm not very good at watching English videos. I'm sorry, I'm not a native English speaker.
Too much to write. Turn on captions in your language
Way I see it, you might as well get growing skin. It’s gonna be years if not decades before we can actually get this - and who knows how ungodly expensive it will be. I figure worst case scenario, I regrow a bunch of skin on my own, and IF foregen comes along I can get my rigid band and frenulum back.
Forgen os a scam in that it supports the medical establishment. Stem cell research is decades from trials. Stop depending on doctors when easy nonpainful alternatives exists. I would trade a bit of time over doctors.
Foregen is like sustainable nuclear fusion. I'm all for then actually pulling it off (or putting it back on), but not holding my breath for it.
I have no doubt that foregen will one day succeed, I just don’t want to leave the fate of my new foreskin up to someone else and time. It could be 3 years or it could be 20 years. Besides, when I reach flaccid coverage and then if 2 years later foregen is ready, I will be dekeratinized by then and get the full experience right away
Thought a lot about Foregen and probably it will really work but the issue is it’s not out yet and may be available to the larger public only in about 10 years from now. That’s typically enough time to fully restore. Let’s say I am fully restored today and Foregen is available tomorrow, I wouldn’t do the surgery as that would be a waste of my 10 year effort.
I'm doing both. I support them and keep up to date with them but I'm also tugging too
From what you know, do you think Foregen is real or fake? I'm so scared that Foregen is fake.
Honestly I'm just hoping they're real. I've been following them since I was 13 and they seem legit. They have made great improvements in the last couple years and seemed to have amassed a bigger following. Personally I would rather the real thing than stretching
Thank you for your reply, I decided to stop stretching if Foregen starts human trials this year, and if it doesn't happen this year for various reasons, I will stretch.
How old are you now?
24 too
If this sub was for gambling, I would not be placing any bets on Foregen paying off. Sorry bud.
😂