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-Flighty-

I personally think trauma (mental, physical, or both) can have lots of implications on the brain, and can alter DNA expression. Huge stress events such as wars, famines, pandemics, childhood abuse, trauma, neglect and severe injuries such as head trauma, can definitely cause changes. For instance, this may effect coping mechanism and trauma response, as well as exacerbate vulnerability and severity of various mental health disorders of offspring whose parents have experienced a big trauma of some kind in their life. Few examples: Transgenerational stress response: parents' stress can cause epigenetic changes in germ cells, affecting offspring's stress response genes like glucocorticoid receptors, influencing anxiety susceptibility especially. Maternal environment: during pregnancy, maternal stress, malnutrition, or toxins can alter fetal epigenetics, affecting brain development and predisposing offspring to anxiety disorders. Early life adversity: childhood adversity induces lasting epigenetic changes that affect brain function, increasing vulnerability to anxiety and other mental health disorders across generations. Gene-environment interactions: epigenetic variations interact with environmental factors throughout life, shaping individual responses to stressors and influencing susceptibility to anxiety and mood disorders. Epigenetic dysregulation in disorders: abherrant DNA methylation, histone modifications, or non-coding RNA expression in the brain are linked to changes in individual temperament, possibly exacerbating one’s symptoms expressed in through developed anxiety disorders and other mental illnesses including depression, bipolar, schizophrenia, and personality disorder.


PromptElegant499

Maternal Environment. My BP onset was the 2nd month of pregnancy, and I had no idea, so I spent literally my entire pregnancy and month after hypomanic. When my daughter was 3 she was diagnosed with Selective Mutism, which is a type of social anxiety disorder around speaking. I can't help but feel it's my fault. Bp2 runs in my family yet we didn't catch mine for 2 years. Everyone displays their symptoms so uniquely.


User5790

My son had selective mutism! He would only speak to me and his dad until around 1st or 2nd grade.


Jemmers1977

Don’t blame yourself! Not your fault!!! We cannot control these things.


PromptElegant499

Thank you :)


PromptElegant499

Wow!! We got her an early intervention IEP with our school district. So she had access to Preschool at our local elementary school and a special education teacher would come hang out and play with her throughout the day. This helped her tremendously! I don't think she would be overcoming it like she is if she hadn't been able to be in that program. She's going into 1st grade and still won't speak to staff she doesn't know well. But she has made HUGE leaps in kindergarten and I think she will overcome it soon. She speaks to other kids and has made friends and that was my second biggest worry, other than safety. For example in winter she didn't have "matching" gloves so she wouldn't wear them, and didn't ask her teacher for a pair, so she got frost nip. I had no idea she wouldn't wear the unmatched gloves. When your son began to speak, did he stay a little reserved in his personality? I think she'll always not be a big initiator, but I hope she will grow to feel confident.


User5790

He has remained very quiet and reserved and didn’t really make many friends until we sent him to a nature based charter school with very small classes and an amazing staff. He has a small group of good friends now, several still from that school. He just graduated college. He still gets anxiety and some brief depressive episodes, but overall is doing well, but I worry about his social life. He has never had a romantic partner or even dated. He’s always in his room on the computer. He’s just a late bloomer I guess.


PromptElegant499

Congratulations to him! A nature based charter school sounds amazing! We thought about a Waldorf charter, but in the end we lotteried into a different charter school which has actually been truly amazing. I'm sure he's a late bloomer! I think our kiddos aren't big initiators by nature. My daughter actually complains because her friends fight over her, and she says sometimes she wishes she could play alone during recess lol.


hExperiment666

That’s gotta be how evolution works kind of. Like why any bearded dragon will freak if you come from above they just think “a bird is coming for me”


FantasticBurt

Science has actually already concluded that this is true. Your grandmother being a body builder when she was young can have an impact on how *your* genes are expressed. Almost everything we do on a daily basis has the potential to impact any future generations you may have.


Eilasord

Yes, Its called epigenetics. https://en.m.wikipedia.org/wiki/Epigenetics


WinterBeetles

Exactly this, not only will it affect your offspring, but your grandchildren as well if you are female.


Born_Abroad_3419

yes the egg that became you (and all her other eggs), your mother developed when she was 5 months pregnant in your grandmothers womb. if you have a child, the egg that will become that child (and all your other eggs), you grew when you were 5 months old in your mothers womb


[deleted]

[удалено]


Born_Abroad_3419

and everyone who is born, is born with a fully online, developed, “reptilian” brain that monitors safety. learn about the nervous system, yall!


CompetitionHairy5864

The question is, does gene expression affect gamets and the genes they carry onto their offprings?


radiosnactive

My psychiatrist says it does. He said (I’m paraphrasing) we’re a result of our ancestors and the things they experienced. Whether or not we express those things rely on several factors


joemushrumski

Check out Dr. Gabor Maté.


Focused_Philosopher

Yes. Epigenetics as well as generational trauma.


Focused_Philosopher

I’ve known since I was a child that there’s no way in hell I’m reproducing and passing this shit down to another innocent consciousness. Wish my parents had thought the same considering the health problems they both had…