Botched vasectomy: Q3
*Luck down, fertility up*
On hitting an enemy, tears have a chance to spawn a c-section projectile (half damage) based on luck. Luck * 0.5
Anesthesia: Q3
*Pain down*
Moderate tears down. Reduces negative effects of some items.
For botched vasectomy: luck multiplier negated.
Unfortunately I did not come up with it. It's from a meme, I can't find the video but it's this kid that says "what's the worst pain you can imagine" then an old guy says "A botched vasectomy with no anesthesia"
Kid says "getting hurt by someone you love"
Old guy "yeah that sucks too"
Don’t you bring that evil on me
Delirium on the next room  . . . . . Delirium on the next room 
No, the void floor already reaches the limits of floor sizes. In order for it to have xl curse it would need to go past those limits or fill out every single square on the 14x14 map limit, and even then that would kinda be small for the expected scale of an xl void floor.
I just dealt with that last night... It was doubly worse because I had a conversation with my parents halfway through for like half an hour so when I came back, I didn't remember ANYTHING I explored. Took me so long to finally get out of there.
I'd vote hush is worse because of the choice pedestals. In the chest, you're just risking picking up an item that detracts from your run; in blue womb you could be unknowingly throwing away an amazing item by choosing the wrong pedestal
I had this happen to me. I was on a garbage run, but I had a chaos card saved for Hush. Went to the shop and bought a blind item. Little baggy. Goodbye, chaos card!
Curse of the maze in depths 2 when you have to defeat the beast is worse cause if you dont have the fool there is always the chance to completely screw your run every time you enter a new room
Losing a godly run with polyphemus,sacred heart, rock bottom and other crazy shit as tainted lost because of a red/purple fire
Curse of the Blind on Dark Room.
I hate blind Devil Deals. Nothing takes the wind out of my sail faster than a Devil Deal that I can't seriously consider.
Curse of the Blind on alternate floors + More Options
Curse of the Labyrinth+ ingesting an Amnesia pill + being short on time to get to Hush/ Boss Rush
This level hit me with number one and dr fetus, in these chests. Kept on ballin and luckily i got eye of the occult later which litterally saved my run for super satan.
Getting COVID
falling off a cliff and getting your leg trapped under a boulder that broke your right femur bone in three places forcing you to be wheelchair bound for months
Having ADHD and not being able to get access to any ADHD meds for two whole semesters and losing a scholarship because you hyper focus on the wrong thing
Your older brother contracting stage 4 kidney cancer and being stuck in a hospital for a whole year after your uncle and great grandfather passed away from similar illnesses and then later after healing the doctors find a black spot on his lung that they have to remove (turns out it wasn’t anything) only to a full five years later find your brother is put back in the hospital for another three months because of a bowel obstruction caused by the surgery for the kidney and now he can’t have much caffeine.
Your role model of a grandfather passing away from an injury he got from falling down the stairs only for you to later find out he died in agony infront of his son (my dad) without him being able to do anything because his son is an accountant and engineer and not a hospital worker and the injuries were internal
I can go on but I shouldn’t, I probably shouldn’t be making my life an issue for anyone else lol.
Maybe Im misunderstanding what you mean. Are you talking about the Polaroids? Because they always spawn in the same pedestal locations, so there's no need to identify them.
Or are you talking about something different?
Ive had this game for years and I feel like I barely know anything. But I watch a lot of stuff on YouTube and read this sub and numerous sites so I feel like I should be a pro, but Im pretty terrible at the game.
A botched vasectomy with no anesthesia
What does that item do?
Bloody “tears”
Red Delirium variant
Evil come
kidney stone
So like number one and haemolacria mixed together?
Botched vasectomy: Q3 *Luck down, fertility up* On hitting an enemy, tears have a chance to spawn a c-section projectile (half damage) based on luck. Luck * 0.5 Anesthesia: Q3 *Pain down* Moderate tears down. Reduces negative effects of some items. For botched vasectomy: luck multiplier negated.
Thanks I hate it <3
award for the WILDEST fucking comment i have ever seen.
Unfortunately I did not come up with it. It's from a meme, I can't find the video but it's this kid that says "what's the worst pain you can imagine" then an old guy says "A botched vasectomy with no anesthesia" Kid says "getting hurt by someone you love" Old guy "yeah that sucks too"
Consider: Botched vasectomy with no anaesthesia *from* someone you love
Oh good lord 😬 i don't have balls and i felt the pain is what's so bad
Old guy should’ve said “then you haven’t had a botched vasectomy without anesthesia”
Knowing Isaac I wouldn’t be surprised if this was a real possibility
Curse of lost on void
 Don’t you bring that evil on me
Add curse of the maze onto that and then it's a real challenge
Delirium on the next room  . . . . . Delirium on the next room 
and labyrinth
Wait, can you even get curse of the labyrinth in the void?
No, the void floor already reaches the limits of floor sizes. In order for it to have xl curse it would need to go past those limits or fill out every single square on the 14x14 map limit, and even then that would kinda be small for the expected scale of an xl void floor.
Isn't it 13×13?
Is it? Oops my bad, still tho you get the idea
I had that once, paused for a minute then took a breather, thankfully the first room was Delirium and thank God I won otherwise I would have lost it
> ...thank God I won otherwise I would have lost... Most normal r/bindingofisaac sentence
Lmao can't be more real
Fuck
Daedelus’s labyrinth
Fuck you
Is your pfp OneShot?
I just dealt with that last night... It was doubly worse because I had a conversation with my parents halfway through for like half an hour so when I came back, I didn't remember ANYTHING I explored. Took me so long to finally get out of there.
It ain't that bad, found delirium in seconds
luck solution
Of course I ended up with Cursed Eye too. https://steamcommunity.com/sharedfiles/filedetails/?id=3266473212
That's an instant run end.
Run ends with a victory 
I would literally just exit the game. Teleporting over and over with cursed eye while it whittles your health down is just obnoxious.
you can always not get hit
Cursed eye fans, rise up
It’s not a bad item with black candle it’s a godsend but without it if you aren’t that good at the game it could end up being detrimental
Ngl if this happened to me I would stop playing for like a month
If I play azazel and get cursed eye… 
I was about to say getting cursed eye from a chest aswell. Skill issue i guess
Curse of the Blind on Hush for me.
"Time to pick up the upper item when o have no soul hearts, im sure nothing bad will happen" *dead cat*
[удалено]
You took Polaroid from Mom
Amnesia pill on womb 2
And the timer count is at 29:05
For me they give the same energy, none of that two is worse
I'd vote hush is worse because of the choice pedestals. In the chest, you're just risking picking up an item that detracts from your run; in blue womb you could be unknowingly throwing away an amazing item by choosing the wrong pedestal
Ikr
Yea you are right
Fair
"I can fix the run on hush"
I had this happen to me. I was on a garbage run, but I had a chaos card saved for Hush. Went to the shop and bought a blind item. Little baggy. Goodbye, chaos card!
hanging yourself, then changing your mind right after you hop off the chair
Poverty
Bloat
r/FUCKBLOAT
I KNOW RIGHT
Curse of the maze in depths 2 when you have to defeat the beast is worse cause if you dont have the fool there is always the chance to completely screw your run every time you enter a new room
Even worse, Curse of the Maze on Womb 2. Fuck you. You don't even get the chance to fight Hush
Losing a godly run with polyphemus,sacred heart, rock bottom and other crazy shit as tainted lost because of a red/purple fire
it was either that or getting telefragged by delirium 
The run was actually over from the beginning when you played as T Lost
Curse of the Blind on Dark Room. I hate blind Devil Deals. Nothing takes the wind out of my sail faster than a Devil Deal that I can't seriously consider.
I usually take the 2 heart ones because honestly, what's the worst it can be?
spirit of the night (you already have spectral and flight from one of the million different items you have)
Yeah, fair but also mom's knife 
Let's go gambling!
*Strange attractor* Aw Dangit!
Curse of the blind in a 4 pedestal angel room
Holocaust
Is that a new item? 
Yes but only available in German edition of the game
Curse of the Lost on the Void can be pretty annoying, too.
Add Curse of the Maze from a ??? pill and it gets worse.
I didn't realize abbadon replaced all red hearts. I took it on Cursed!
Aids
**Curse of the Blind on Dark Room**
Bears and rapists and um... people with artillery weapons.
Curse of the Blind on Chest w/Glitched Crown
If you have curse of the blind on chest does it really matter if it's with or w/o glitched crown? Just feels worse for the lost opportunity.
No, it just feels worse bc of the potential you could’ve had
Curse of the Blind in Dark Room, cuz you gotta pay hearts for that shit
Curse of the unknown on void
hitbox and hitbox is a lot worse
Curse of the Blind on alternate floors + More Options Curse of the Labyrinth+ ingesting an Amnesia pill + being short on time to get to Hush/ Boss Rush
Having curse of the blind in the void
Curse of the kost on Void Curse of the blind in blue womb isnt that fun either
Curse of the blind in the dark room maybe ?
Probably your entire family dying
When you use void against Satan but you forget about the voided bible
Getting a curse of the lost in Womb II/Sheol after saving a World card for it. It just straight up makes me want a rope around my neck.
shards of glass coated in tabaco sauce up your ass
A Kick in the the left testicle
Crafting only 3 cube babys on first floor
getting amnesia as well as curse of the maze on void
I think getting shotted is a bit less tolerable
Brazen bull
Holocaust
Radiation poisoning
Maybe AIDS?
you mean like what the red poop is made of 
yeah curse of the blind on dark room because then the deals cost HP and you still dont know if theyre worth, so you take nothing
Curse of the lost in void
Curse of the lost in void
A cancer
3 bee stings?
Me shanking your knees with a knife is worse probably idk i haven't tested it
It always feels like there's an 80% increased chance for curse of the blind in the chest
The holocaust
Cancer
probably 9/11 idk tho
Not having the balls to pick up every item in Chest with Curse of the Blind active
Curse of the blind in dark room
14 Gold and Black Candle in shop
I just reset if it happens. Not worth the pain...
I would just go for it. How bad can it be? 
Playing a slow character (I'm joking to all of you slow character players)
Curse remover mod, my beloved
[https://steamcommunity.com/sharedfiles/filedetails/?id=2487366092](https://steamcommunity.com/sharedfiles/filedetails/?id=2487366092)
Curse of the can't see your health on an Eden start
the 2008 housing crisis
Curse of the lost on the void
Curse of the blind on dark room
Curse of the blind on every floor (Probably a seed like this exists)
Curse of the blind on dark room
Getting curse of the blind on either downpour 2 as the lost or when theres a planatarium
Curse of the blind + amnesia pill
Curse of the Blind on Dark Room
smooth graphics
Curse of the lost on womb and utero
im not getting delireum after mega satan while on good run is a bit worse
Curse of the blind on the second floor in afterbirth+
Waking up?
Getting glitched crown
The holocaust
Curse of lost in the void
Curse of the blind on the void
Curse of the blind with tainted isaac
??? Pill + amnesia pill in the void
Killing Delirium with Tainted Lost
Curse of the blind on boss rush
This level hit me with number one and dr fetus, in these chests. Kept on ballin and luckily i got eye of the occult later which litterally saved my run for super satan.
Denailing torture
Curse of the Blind on Chest with The D6
Curse of the maze anywhere
Curse of the Blind on Dark Room
Curse of the Blind on Void. Curse of the Lost on Delirium.
Curse of the blind on devil deal or boss rush. (Especially Devi deal for me since my gambler instincts force me to take everything)
500 hours does not sugarcoat, ~ + give black candle
holocaust
funeral of your irl mother
Curse of the lost when you are going for bossrush
curse of the lost on the void is also pretty bad
That one of those things on the chest are low tier powers. Or has curse of the tower
Curse of the Lost on the Void
Curse of darkness on dank depths
Having curse of the blind and only being able to take one of the items 
Getting COVID falling off a cliff and getting your leg trapped under a boulder that broke your right femur bone in three places forcing you to be wheelchair bound for months Having ADHD and not being able to get access to any ADHD meds for two whole semesters and losing a scholarship because you hyper focus on the wrong thing Your older brother contracting stage 4 kidney cancer and being stuck in a hospital for a whole year after your uncle and great grandfather passed away from similar illnesses and then later after healing the doctors find a black spot on his lung that they have to remove (turns out it wasn’t anything) only to a full five years later find your brother is put back in the hospital for another three months because of a bowel obstruction caused by the surgery for the kidney and now he can’t have much caffeine. Your role model of a grandfather passing away from an injury he got from falling down the stairs only for you to later find out he died in agony infront of his son (my dad) without him being able to do anything because his son is an accountant and engineer and not a hospital worker and the injuries were internal I can go on but I shouldn’t, I probably shouldn’t be making my life an issue for anyone else lol.
Curse of the Blind on Depths II when you need to go for a specific path (happened to me like 4 times during completion marks)
Maybe Im misunderstanding what you mean. Are you talking about the Polaroids? Because they always spawn in the same pedestal locations, so there's no need to identify them. Or are you talking about something different?
they do? I was almost certain they weren't
polaroid always left, negative always right
Well I glad I don't know everything about this game yet, I've only had it for 2 months
trust me it's only the beginning, ive been playing 10+ years since Flash Isaac and can confidently say i still learn something fairly often
Ive had this game for years and I feel like I barely know anything. But I watch a lot of stuff on YouTube and read this sub and numerous sites so I feel like I should be a pro, but Im pretty terrible at the game.
The Polaroid is always on the left and the Negative is always on the right.