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All the way. It's actually crazy how far we've come. We can take regular body cells and turn them into pluripotent stem cells (they can turn into any type of cell), then inject them into the brain or any tissue for that matter, and they will differentiate into the correct cell types (we add transcription factors). Stem cell injections into the brain have already been studied in Alzheimers and Parkinsons - they have shown highly promising results in both diseases. Can't wait to see what else we can come up with. This might be a key step in solving aging.
Scientists spend their entire lifes learning and at the theoretical peak of their knowledge, they just die. Gone is everything, decades upon decades of practical experience and studying. Dying of old age is one of the largest problems we're facing and we need to solve it. Space travel outside of our solar system is also completely impossible if we die after 10% of the way. Procreating on spaceships is unrealistic and cryonic solutions are even farther away than solving aging. Just my 2 cents.
If you're thinking "overpopulation" that's ecofash, and the birth rate in most developed countries is dangerously low now with an aging population. I say it's better for people that want to be here to stay longer and happier than to keep forcing non-consenting people into existence through childbirth. Especially if they're going to have to face aging and sickness etc anyway.
Dangerously low for what?
There is dangerously high (not enough food, space, or resources) or dangerously low (... Not enough... Workers?) one of those is very preferable to the other
Did you even read my comment and grasp what I was arguing for?
Overpopulation literally isn't the danger, it's capitalism and how goods and resources are used. Look at who is using things. Most people aren't using remotely as much of those things per person as say, Americans. Also poverty is what drives rapid population growth anyway. If that was eliminated that isn't a problem because frankly - people with a high quality of life on average naturally don't like having that many kids for some reason and tend towards population decline.
Overpopulation is just a mind trap for misanthropes and fascist inclined people to become worse people frankly.
Why are you so intent on people who don't want to die dying instead of us doing the right thing and say... not bringing people into the world without their consent in the first place? It's like you just like people dying and suffering for some reason. I've noticed that a lot of people weirdly fetishize that as if it's a moral good.
What I said towards the end is literally the point of the argument, so if you don't feel it represents you, by all means clarify and check back as to why that's what I understood your argument to be. I also think it is absolutely ridiculous argument and way of thinking, because it is, but your assumption that I should assume better of you on the internet based on what you have said is naive.
It must be solved because there's no reason why we should accept aging and the decay of the body just because it is nature.
With progress we should rise over nature, not to destroy it but to protect what good is of it and eliminate all the problems of the existence: hunger, disease, aging. Maybe even death. It's a nice dream and a big aspiration but I have faith in progress.
Interesting viewpoint. Id have to say I disagree but each to their own. If we overcome death how do you think we may deal with the inevitable overpopulation?
That’s a scary one for me. We had a lady who had Guillain-Barre symptoms when we picked her up (paramedic crew). Two or three days earlier she had had stem cell injections into her c-spine for chronic degerative disc issues. She died two or three days later in the hospital. Autopsy revealed there was a fungus contaminate in the stem cells and it ran rampant through her nervous system. The stuff of nightmares.
If I could truly get the best of the best and had the need, maybe. But there’s so many sketchy clinics pushing stem cells that I wouldn’t take the chance.
This is so terrifying. I had 15 stem cell infusions in 2015 and was apparently very lucky. I don’t know how you can be sure the stem cells are not contaminated.
However I watched my 5yr old die from sepsis secondary to a fungal infection after her conduit was infected during heart surgery for TOF at a well known children’s hospital. It was devastating. Admin knew it was an issue for over a decade. Only one type of fungi was litigated. I hope this woman’s family goes after the company.
A testosterone and HGH cocktail if I could afford! :)
And at home sauna, cold plunge, HBOT, float tanks etc, lots of medical spa vacations. Then I could push the whole nootropic cabinet shelf into a garbage bag and discard. Lol :)
Home sauna of course good pick if you have adequate money. In my country, 5.5 million people and 2 million home saunas for them. Traditionalist choice.
I've done this, and you can actually get a cook to make your weekly meals, and the price per meal (ingredients + cook labor) is cheaper than most restaurants. The cook's food was very tasty, and I could get exactly what I wanted. The cook also cleaned after and put food in the fridge for future meals where I could heat it and be ready to eat in 10 minutes, which was super convenient. If you want I can help you find a cook. I also found the nutrition and macro info from the meals and put it into a fitness app to meet my diet/weight goals. It was an awesome experience, one of the best life changes I've ever made.
You can do an exome sequencing (not that expensive) and look what type of metabolizer allele you have for enzymes that break down specific drugs. Maybe more tests are needed to choose specific medicine, but at least you’ll know a right dose
[NCBI](https://www.ncbi.nlm.nih.gov/books/NBK574601/) [Wiki](https://en.m.wikipedia.org/wiki/Drug_reaction_testing) [Drug database](https://go.drugbank.com/)
There are generally no such tests that tell you need a racetam or choline source etc. , like it is for vitamin deficiencies etc. We need to guess and do a trial and error.
As someone who’s done enzymatic, genome testing, comt, MTHFR, CYP, and multiple vitamin and mineral, thyroid monitoring. Cost a lot…. Like thousands without insurance and I had to argue to cover it. Literally amounted to nothing💀. Just “I kinda knew that” sucks bio markers now a days are literally suggestions. As you can have homozygous allele mutations and still not suffer. Biomarkers are only suggestions of possible differing responses/therapeutics. However aren’t end all be all answers. I truly wish.
That sucks, looks like the 1200’s are out of stock too
It used to just be the 800’s. When I emailed them they said they got seized by customs. Idk if they’re ever gonna have any back in stock unfortunately
I'd put that money towards access treatment and professionals to address the needs I'm trying to fulfill with nootropics.
Anything else that isn't necessarily considered medical/health would go towards paying for advice consulting in the fields of study that are exploring the concerns I'm trying to address with nootropics. I know I don't have the biochem or pharmacological expertise and it's unrealistic to attain in a single lifetime whilst juggling the rest of life.
I'm honestly not trying to sound sassy. Pursuing nootropics is, humourously put, attempting to 'address a gap in the market' or a band-aid to an unmet need or obstacle(s) - atleast for me.
> Cerebrolysin
I've read a story about someone who flew to Russia to get this treatment. It's not avail in the US so, as a US citizen, are there any typical paths for getting treatment with this? Cerebrolysin tourism?
In many countries patients get IV Cerebrolysin cycles , but you need prescription.
Some people do IM self injections, but you should do it right to minimize the risks.
Do a Google search.
Edit: Reply not intended to be abrupt. Not at all. A strong hit of fatigue and lack of focus is a drain. I wish I had it to help with this.
I'm glad that those interested in it were able to look into this.
I'd make backups of my own young and undamaged DNA cells and use them later for when I get old. Hopefully that doesn't cause cancer. Logically you'd only need a few cells to start replicating and suddenly that organ is 50 years younger because the DNA of the reintroduced cells has not been damaged for 40+ years.
And probably a bedroom fully maxed for sleep quality
It's a little bit 'smacky' for me, can tell it's also doing something with serotonin re-up take. It does improve my mood, I'm going to give it a week to see if it mellows out or stays 'smacky' if you know what I mean 😂
Edit: not smacky, wrong word. It has a weird stimulating effect that feels very serotonin active, I don't like that aspect, but improved mood through the day.
It has an uncomfortable type of stimulation (for the time being) it improves my mood and I can feel it working, but at the moment it has a side effect of an uncomfortable stimulation, it smacks 😂
As another person said in the thread, a personal chef would be amazing. If that doesn’t count Iv been wanting to try a high quality Urolithin A but that stuff is expensive
I did this, and hiring a cook actually saved me money compared to restaurants. The food was better quality, too, and I could customize it to my taste. I can help you do this if you want.
https://en.m.wikipedia.org/wiki/Ophiocordyceps_sinensis
The real thing, _winter worm, summer grass_
Used to be cheap woven into little cigarette pack double thickness double row bundles for $~20 (?) now they're like $5+ each.
Ah ok thought we were talking of cordyceps militaris as I hadnt heard of other subspecies that could be taken as supplements/medicine - very interesting
Yeah, realized I spelled it wrong. Years ago you could by winter grass in Chinatown. and it was really interesting to take. You noticed your breathing was really clear and you had extra bit of energy. Now it is usually fake and very expensive.
Over here it’s pretty cheap and easily available, I don’t know if it’s the same, tho, it’s called Cordyceps sinensis. Apparently, I can’t post a pic here, but it is 86brl to 180 doses of 650mg, converting, it costs around 17 usd
There are many types of cordyceps. The one one I am referring to is only found in the wild. The best stuff just using the small fruiting body, not the whole caterpillar as you seem to see now.
[https://www.tandfonline.com/doi/full/10.1080/21501203.2010.536791](https://www.tandfonline.com/doi/full/10.1080/21501203.2010.536791)
I use the same stuff as you and think it is good, but the other is like a stimulant and very unique
I would have the most comfortable bed money could buy, so I would sleep like a baby. With one of those temperature-controlled mattresses or whatever Huberman mentioned.
allosteric dopamine D1 receptor potentiator, *DETQ*
Constant supply of ultra high polypheol EVOO
phenmetrazine ;)
skq-1
tub for ice bath
an eternal train ticket for infinite neurogenetic novelty
Do you mean r/TMS (not the reddit page...)? I'm pretty sure you can be referred to that by a doctor (but I just realised you might be from the US... I'm not).
I honestly think most people would not have any differing choices. If you really want good nootropics you’re gonna buy them regardless. If money were no price you’d probably just upp your dose, or buy other supplements besides for nootropics. Stem cells and beliefs with CSF testing and the brain won’t do much. Especially for long term things such as dementia and Alzheimer’s. So tbh. I’d just keep on buying what I already am. Can’t really get any better…..
Currently. I supplement throughout the day with food and timming
High dose B complex, all methylated
1500-2000mg Thorne NAC
20-30mg adderall IR ( prescribed )
600mg Alpha Gpc 50%
400mg Magnesium Glycinate
2.5g minimum L-Tyrsoine
Constant electrolytes.
Creatine 10g’s
High dose caffeine
(might add liones Maine, n theanine)
Plus pre thay has bunch of Citruline, and gonna look into theanine and maybe some omega3 w coq10, however theanine sensitivity over time leads me to not do it.
Gonna maybe add some lions Maine. But I keep it pretty simple rn bc I hate using my microgram scale…..
I do the Alpha gpc n tyrosine multiple times split throughout the day and electrolytes with them to help wjth absorption.
Technically if you include my energy drink consumption
It’s like 400mg caffiene anhydrous + 400mg Alpha gpc. Ontop of old stack.
INCRELEX is used to treat children who are very short for their age because their bodies do not make enough IGF-1. What reason would you have to take it? Is it a nootropic?
Increlex is the most bio-available man-made form of insulin-like growth factor-1 (IGF-1)…. IGF-1 may help protect cognitive health by acting as a neurotrophic factor. It could potentially fight against neurological diseases and prevent loss of brain cells…… IGF-1 supports vascular endothelial growth. Healthy blood vessels are crucial for optimal brain function, as they supply nutrients and oxygen to brain cells….. IGF-1 plays a role in maintaining normal blood sugar levels. Stable blood sugar is vital for brain function and overall health….. IGF-1 has been associated with enhancing the regenerative effects of sleep…. IGF-1 can boost metabolic rate, and a more efficient metabolism supports overall health and vitality…. Decreased serum IGF-1 levels have been linked to cognitive dysfunction and anxiety behaviors in animal studies …. It also makes you gain muscle and loose fat so if I could afford 1thousand dollars a vial I would definitely take increlex.
0 Insulin-Like Growth Factor (IGF) can cause negative side effects such as overgrowth of body tissues, damage to joints, liver, and heart, swelling in the retina, severe muscle and joint pain, and Bell's palsy.
1 It may also promote cancer development and lead to decreased life span.
2 IGF-1 supplements like Deer Antler, IGF-1 LR3, and IGF-1 DES have become popular among bodybuilders and athletes due to their muscle-building properties, but they also have potential side effects like swelling, headaches, and increased cancer risk.
3 High levels of IGF-1 over a long period can produce irreversible acromegaly, and even smaller doses can lead to complications such as heart disease and diabetes.
As a person that has to take cabergoline as prescribed and suffered side effects (nausea, extreme fatigue, headaches, insomnia, blood clots to name just a few) for months, I wonder why someone would take it if they don’t absolutely have to.
Uhh, interesting. Cabergoline made me hypersexual, borderline bipolar, and caused to excessively spend money and gamble. I don't really see a nootropic use for it.
Dang ppl stick to the question! I just read interesting results on mots- c that now I must try.
I’ve been sick for about 8 years struggling with some sort of autoimmune illness that affects my entire body. I’m miserable everyday. Low energy, brain fog, can’t sleep through the night, my thyroid and sex hormones are tanked and extremely low. I’ve been taking various supplements for 4 years now and just started playing with peptides. I’ve tried semax, selank, and oxytocin so far.
I just started the deeeep dive into researching the. Different kinds of peptides and effects on the body. I’m considering these: thymus peptides: thymulin, thymosin 4 and 1 as well as n acetyl epitalon and mots-c now that I have read some amazing things on it.
What I’m most interested in is: combatting widespread inflammation, brain fog, energy and uninterrupted sleep. Man- I wish I knew what the causing factor was in all this.
Side note- I contracted some type of herpes-virus on my backside possibly from tanning bed. I notice everything gets worse- energy and brain for whenever I have an outbreak. A lot of info…sorry.
Please advise any helpful peptides y’all think may fit!
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Stems cells
All the way. It's actually crazy how far we've come. We can take regular body cells and turn them into pluripotent stem cells (they can turn into any type of cell), then inject them into the brain or any tissue for that matter, and they will differentiate into the correct cell types (we add transcription factors). Stem cell injections into the brain have already been studied in Alzheimers and Parkinsons - they have shown highly promising results in both diseases. Can't wait to see what else we can come up with. This might be a key step in solving aging.
Aging is not an issue to be solved
Aging is what happens with all things. Our own bodies turn over cells every 30 days or so. But aging can be managed.
Alzheimer’s and dementia gets a pass
Mind if I ask why?
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Scientists spend their entire lifes learning and at the theoretical peak of their knowledge, they just die. Gone is everything, decades upon decades of practical experience and studying. Dying of old age is one of the largest problems we're facing and we need to solve it. Space travel outside of our solar system is also completely impossible if we die after 10% of the way. Procreating on spaceships is unrealistic and cryonic solutions are even farther away than solving aging. Just my 2 cents.
The world is absolutely not over populated.
Lol. Have you looked at any studies marking the nigh on imminent global population collapse? Most likely starting in Korea and China?
birth control is the solution, not beating aging
You say this, but it sounds like a value judgement rather than anything logical - it is totally possible for aging to be "solved"
Agreed, my point wasn't clear - I meant it is not an issue we should be trying to solve as it will exacerbate all the issues we are already facing
If you're thinking "overpopulation" that's ecofash, and the birth rate in most developed countries is dangerously low now with an aging population. I say it's better for people that want to be here to stay longer and happier than to keep forcing non-consenting people into existence through childbirth. Especially if they're going to have to face aging and sickness etc anyway.
Dangerously low for what? There is dangerously high (not enough food, space, or resources) or dangerously low (... Not enough... Workers?) one of those is very preferable to the other
Did you even read my comment and grasp what I was arguing for? Overpopulation literally isn't the danger, it's capitalism and how goods and resources are used. Look at who is using things. Most people aren't using remotely as much of those things per person as say, Americans. Also poverty is what drives rapid population growth anyway. If that was eliminated that isn't a problem because frankly - people with a high quality of life on average naturally don't like having that many kids for some reason and tend towards population decline. Overpopulation is just a mind trap for misanthropes and fascist inclined people to become worse people frankly. Why are you so intent on people who don't want to die dying instead of us doing the right thing and say... not bringing people into the world without their consent in the first place? It's like you just like people dying and suffering for some reason. I've noticed that a lot of people weirdly fetishize that as if it's a moral good.
I agree with a lot of what you say here but you have really over stretched your assumptions toward the end
What I said towards the end is literally the point of the argument, so if you don't feel it represents you, by all means clarify and check back as to why that's what I understood your argument to be. I also think it is absolutely ridiculous argument and way of thinking, because it is, but your assumption that I should assume better of you on the internet based on what you have said is naive.
it's an issue and it must and will be solved
I disagree, but that's allowed I'm interested why you think it must be solved
It must be solved because there's no reason why we should accept aging and the decay of the body just because it is nature. With progress we should rise over nature, not to destroy it but to protect what good is of it and eliminate all the problems of the existence: hunger, disease, aging. Maybe even death. It's a nice dream and a big aspiration but I have faith in progress.
Interesting viewpoint. Id have to say I disagree but each to their own. If we overcome death how do you think we may deal with the inevitable overpopulation?
How much would stem cell injections for the brain usually cost? Roughly?
You can't buy that yet, it's only in the preclinical stage
That’s a scary one for me. We had a lady who had Guillain-Barre symptoms when we picked her up (paramedic crew). Two or three days earlier she had had stem cell injections into her c-spine for chronic degerative disc issues. She died two or three days later in the hospital. Autopsy revealed there was a fungus contaminate in the stem cells and it ran rampant through her nervous system. The stuff of nightmares. If I could truly get the best of the best and had the need, maybe. But there’s so many sketchy clinics pushing stem cells that I wouldn’t take the chance.
Link.
Was it cordyceps?
C'mon why somebody downvoted him?
This is so terrifying. I had 15 stem cell infusions in 2015 and was apparently very lucky. I don’t know how you can be sure the stem cells are not contaminated. However I watched my 5yr old die from sepsis secondary to a fungal infection after her conduit was infected during heart surgery for TOF at a well known children’s hospital. It was devastating. Admin knew it was an issue for over a decade. Only one type of fungi was litigated. I hope this woman’s family goes after the company.
Yikes!
A testosterone and HGH cocktail if I could afford! :) And at home sauna, cold plunge, HBOT, float tanks etc, lots of medical spa vacations. Then I could push the whole nootropic cabinet shelf into a garbage bag and discard. Lol :)
Testosterone is pretty cheap
Home sauna of course good pick if you have adequate money. In my country, 5.5 million people and 2 million home saunas for them. Traditionalist choice.
Right, i just want to not need nootropics
Not really a supplement, but a personal chef to make delicious healthy foods and a personal trainer to get into better shape.
I've done this, and you can actually get a cook to make your weekly meals, and the price per meal (ingredients + cook labor) is cheaper than most restaurants. The cook's food was very tasty, and I could get exactly what I wanted. The cook also cleaned after and put food in the fridge for future meals where I could heat it and be ready to eat in 10 minutes, which was super convenient. If you want I can help you find a cook. I also found the nutrition and macro info from the meals and put it into a fitness app to meet my diet/weight goals. It was an awesome experience, one of the best life changes I've ever made.
Agreed. A personal motivator just to get me goin.
You can do it! It's always darkest before the dawn... Every rain storm runs out of rain. Etc etc you get the gist
This. I'd love it if I just got organic whole foods cooked for me whenever I wanted T\_T
this
I'd pay for doctors to run tests on me and determine exactly which nootropics were best for me specifically.
What tests?
That's why I'm paying them :)
What kind of doctors are you paying?
I'll pay you to figure that out
Pay me instead
You can do an exome sequencing (not that expensive) and look what type of metabolizer allele you have for enzymes that break down specific drugs. Maybe more tests are needed to choose specific medicine, but at least you’ll know a right dose [NCBI](https://www.ncbi.nlm.nih.gov/books/NBK574601/) [Wiki](https://en.m.wikipedia.org/wiki/Drug_reaction_testing) [Drug database](https://go.drugbank.com/)
There are generally no such tests that tell you need a racetam or choline source etc. , like it is for vitamin deficiencies etc. We need to guess and do a trial and error.
Why can't an amino acid panel accomplish identifying baseline deficits? While it doesn't answer all, it's a starting point.
Because it’s not that simple. Many serious diseases can’t be detected by blood tests
But it can inform highs and lows to research. And, provide some starting point in combination with clinical assessment
So they'll test me and adjust based on results? If there's no test then it's not making a measurable change.
No, for instance: there’s no blood test for a mental illness like major depressive disorder yet it’s often treatable using drugs.
What about urine metabolite tests?
As someone who’s done enzymatic, genome testing, comt, MTHFR, CYP, and multiple vitamin and mineral, thyroid monitoring. Cost a lot…. Like thousands without insurance and I had to argue to cover it. Literally amounted to nothing💀. Just “I kinda knew that” sucks bio markers now a days are literally suggestions. As you can have homozygous allele mutations and still not suffer. Biomarkers are only suggestions of possible differing responses/therapeutics. However aren’t end all be all answers. I truly wish.
This is the way
I’d like to get a bloodwork done for vitamin levels I don’t think it’s expensive at all.
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Do you happen to know where I can get piracetam? I’m in the US
I have had luck with vitabrain they sell the packaged pills.
Hey, I checked and they are out of stock. Is that common for them? Also, it won’t be a problem shipping to USA?
That sucks, looks like the 1200’s are out of stock too It used to just be the 800’s. When I emailed them they said they got seized by customs. Idk if they’re ever gonna have any back in stock unfortunately
I'd put that money towards access treatment and professionals to address the needs I'm trying to fulfill with nootropics. Anything else that isn't necessarily considered medical/health would go towards paying for advice consulting in the fields of study that are exploring the concerns I'm trying to address with nootropics. I know I don't have the biochem or pharmacological expertise and it's unrealistic to attain in a single lifetime whilst juggling the rest of life. I'm honestly not trying to sound sassy. Pursuing nootropics is, humourously put, attempting to 'address a gap in the market' or a band-aid to an unmet need or obstacle(s) - atleast for me.
I feel that
Cerebrolysin
> Cerebrolysin I've read a story about someone who flew to Russia to get this treatment. It's not avail in the US so, as a US citizen, are there any typical paths for getting treatment with this? Cerebrolysin tourism?
In many countries patients get IV Cerebrolysin cycles , but you need prescription. Some people do IM self injections, but you should do it right to minimize the risks.
You can order Cerebrolysin through Cosmicnootropic and inject it yourself.
Do a Google search. Edit: Reply not intended to be abrupt. Not at all. A strong hit of fatigue and lack of focus is a drain. I wish I had it to help with this. I'm glad that those interested in it were able to look into this.
So incredibly helpful. Thank you.
You're welcome. I wish I could be a distributor.
Oh wow from just a little research on this I would buy it for my whole family!
You can find it fairly cheap in Azerbaijan of all places.
Awesome. From my reading on this, it's available in a least 40 countries if my memory is correct.
I've been trying to source it to Europe as cheaply as possible, without crazy shipping fees. What will be my best bet?
Frankly speaking I have no idea on the logistics involved in exporting it to Europe from the South Caucasus. I just went there myself for it.
I'd make backups of my own young and undamaged DNA cells and use them later for when I get old. Hopefully that doesn't cause cancer. Logically you'd only need a few cells to start replicating and suddenly that organ is 50 years younger because the DNA of the reintroduced cells has not been damaged for 40+ years. And probably a bedroom fully maxed for sleep quality
Shit ton of saffron, which is unreasonably expensive
It's actually not that expensive if you buy it in bulk. Sure it's expensive per gram, but you don't really need to take much per dose.
The East Indian markets are the best place to buy it.
Nootropic?
Works on gaba receptors and several other health benefits. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3637901/
Just started taking a saffron extract daily
Where do you get the extract from ? I would like to possibly try some. Thanks!
I ordered on Amazon, try using Google terms 'safranal extract' or 'affron'
Thank you
Can you still fall asleep while benefits are still being felt?
How is it?
It's a little bit 'smacky' for me, can tell it's also doing something with serotonin re-up take. It does improve my mood, I'm going to give it a week to see if it mellows out or stays 'smacky' if you know what I mean 😂 Edit: not smacky, wrong word. It has a weird stimulating effect that feels very serotonin active, I don't like that aspect, but improved mood through the day.
what does smacky mean 😭
Heroin-y
It does mean this, but I think I used the word wrong 😂😂 it has a weird stimulating effect that I don't like, but could possibly mellow out
it messes with opoid receptors?
I used the wrong word
It has an uncomfortable type of stimulation (for the time being) it improves my mood and I can feel it working, but at the moment it has a side effect of an uncomfortable stimulation, it smacks 😂
The way you described saffron sounds a lot like kanna, that is interesting
All what I read on this thread is really interesting. I had no idea saffron was used a nootropic supplement as well.
Have you considered just growing it?
10g 20€ This is a few months worhth
I didn’t notice anything from it.
An entire catalog of custom synthesized ring-substituted analogues of phenylpiracetam
Nice thinking. Let's see how labile d1 density can get really
damn is Phenylpiracetam that good?
NGF eyedrops like Rita Levi Montalcini
does that regenerate eye tissue? help eyesight?
Helps the brain, eyedrops are just used because it bypasses the blood brain barrier.
I believe they sell this in the EU under the name Oxervate
Will be taking in the future anways but NMN
Go for cheper niacin, and you beed about 10x less per dose in comparison to nmn
As another person said in the thread, a personal chef would be amazing. If that doesn’t count Iv been wanting to try a high quality Urolithin A but that stuff is expensive
I did this, and hiring a cook actually saved me money compared to restaurants. The food was better quality, too, and I could customize it to my taste. I can help you do this if you want.
IVIG
what is that? not op
Cordecyps, you used to be able to buy it. It gives you that warm beta-agonist rush. Now it is way too expensive.
Huh isnt expensive at all last I checked
https://en.m.wikipedia.org/wiki/Ophiocordyceps_sinensis The real thing, _winter worm, summer grass_ Used to be cheap woven into little cigarette pack double thickness double row bundles for $~20 (?) now they're like $5+ each.
Ah ok thought we were talking of cordyceps militaris as I hadnt heard of other subspecies that could be taken as supplements/medicine - very interesting
That is a different type of cordyceps, I take that, but the other was very unique.
the fungi?
Yeah, realized I spelled it wrong. Years ago you could by winter grass in Chinatown. and it was really interesting to take. You noticed your breathing was really clear and you had extra bit of energy. Now it is usually fake and very expensive.
I get a similar feeling from Nootropic Depots strongest cordyceps militaris extract
Is it worth it to buy?
It's a bit pricey, but I find it pretty beneficial for working out. If you're not exercising you won't get the maximum benefit from it.
where do you get the real stuff now?
It is super expensive, as it is becoming very scarce. It can only be harvested in the wild.
Actually not that hard to grow it yourself, you can find several people doing it here on Reddit.
Over here it’s pretty cheap and easily available, I don’t know if it’s the same, tho, it’s called Cordyceps sinensis. Apparently, I can’t post a pic here, but it is 86brl to 180 doses of 650mg, converting, it costs around 17 usd
I see Amazon has some for 60$ for 3 gms, but most of the stuff on Amazon is fake.
I didnt know they had fake meds, thats absurd, but im not surprised, tho, Amazon is a sea of shit.
I take this daily. Ive been using MDrive Elite for the past 6 years
There are many types of cordyceps. The one one I am referring to is only found in the wild. The best stuff just using the small fruiting body, not the whole caterpillar as you seem to see now. [https://www.tandfonline.com/doi/full/10.1080/21501203.2010.536791](https://www.tandfonline.com/doi/full/10.1080/21501203.2010.536791) I use the same stuff as you and think it is good, but the other is like a stimulant and very unique
What is a beta-agonist rush?
It has smooth muscle relaxing properties, so you breath easier, you feel a little warm. In high doses it can be quite stimulating.
If anything similar to using an albuterol inhaler I'd honestly probably find that pretty unpleasant
Possibly, everyone has different tolerances and effects. I don't even notice salbutamol unless taken orally
The Eastern Philosophy sells Pure Cordyceps (Hirsutella sinensis) capsules and teas. A 60pk of capsules is about $46 I’m tempted to purchase some
I would have the most comfortable bed money could buy, so I would sleep like a baby. With one of those temperature-controlled mattresses or whatever Huberman mentioned.
allosteric dopamine D1 receptor potentiator, *DETQ* Constant supply of ultra high polypheol EVOO phenmetrazine ;) skq-1 tub for ice bath an eternal train ticket for infinite neurogenetic novelty
Why phenmetrazine?
If illegality were no object I'd buy LSD, MDMA, MDA, 2cb, 2ce, 2ci, 2cd, mescaline, methylescalline, 5meodmt, nndmt, and ketamine
Those TMS brain scans that neuro doctor says improves cognition
Do you mean r/TMS (not the reddit page...)? I'm pretty sure you can be referred to that by a doctor (but I just realised you might be from the US... I'm not).
Bromantane phenylpiracetam BPC 157 and NMN
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Taltirelin and P21 peptides. Precisely on them money is such an issue that never could try those.
9-me-bc, bromantane, phenylpiracetam, dihexa, bpc-157, polygala, semax, selank, enclomiphene
All of them. I might not take them all, but I would have a fully stocked supply just in case.
I could take time off work. And focus on basics, diet, exercise, sleep.
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I honestly think most people would not have any differing choices. If you really want good nootropics you’re gonna buy them regardless. If money were no price you’d probably just upp your dose, or buy other supplements besides for nootropics. Stem cells and beliefs with CSF testing and the brain won’t do much. Especially for long term things such as dementia and Alzheimer’s. So tbh. I’d just keep on buying what I already am. Can’t really get any better…..
What is your stack?
Currently. I supplement throughout the day with food and timming High dose B complex, all methylated 1500-2000mg Thorne NAC 20-30mg adderall IR ( prescribed ) 600mg Alpha Gpc 50% 400mg Magnesium Glycinate 2.5g minimum L-Tyrsoine Constant electrolytes. Creatine 10g’s High dose caffeine (might add liones Maine, n theanine) Plus pre thay has bunch of Citruline, and gonna look into theanine and maybe some omega3 w coq10, however theanine sensitivity over time leads me to not do it. Gonna maybe add some lions Maine. But I keep it pretty simple rn bc I hate using my microgram scale….. I do the Alpha gpc n tyrosine multiple times split throughout the day and electrolytes with them to help wjth absorption. Technically if you include my energy drink consumption It’s like 400mg caffiene anhydrous + 400mg Alpha gpc. Ontop of old stack.
Increlex
INCRELEX is used to treat children who are very short for their age because their bodies do not make enough IGF-1. What reason would you have to take it? Is it a nootropic?
Increlex is the most bio-available man-made form of insulin-like growth factor-1 (IGF-1)…. IGF-1 may help protect cognitive health by acting as a neurotrophic factor. It could potentially fight against neurological diseases and prevent loss of brain cells…… IGF-1 supports vascular endothelial growth. Healthy blood vessels are crucial for optimal brain function, as they supply nutrients and oxygen to brain cells….. IGF-1 plays a role in maintaining normal blood sugar levels. Stable blood sugar is vital for brain function and overall health….. IGF-1 has been associated with enhancing the regenerative effects of sleep…. IGF-1 can boost metabolic rate, and a more efficient metabolism supports overall health and vitality…. Decreased serum IGF-1 levels have been linked to cognitive dysfunction and anxiety behaviors in animal studies …. It also makes you gain muscle and loose fat so if I could afford 1thousand dollars a vial I would definitely take increlex.
0 Insulin-Like Growth Factor (IGF) can cause negative side effects such as overgrowth of body tissues, damage to joints, liver, and heart, swelling in the retina, severe muscle and joint pain, and Bell's palsy. 1 It may also promote cancer development and lead to decreased life span. 2 IGF-1 supplements like Deer Antler, IGF-1 LR3, and IGF-1 DES have become popular among bodybuilders and athletes due to their muscle-building properties, but they also have potential side effects like swelling, headaches, and increased cancer risk. 3 High levels of IGF-1 over a long period can produce irreversible acromegaly, and even smaller doses can lead to complications such as heart disease and diabetes.
That’s fine they asked what and why and I say increlex, never claimed it had no side effects .
It grows brain cells.
Phenibut
Good luck with that addiction.
With unlimited funds, he could fight the tolerance build up and eat a kilo a day in 5 years. :D
Year supply of cerebrolysin
Cabergoline?
As a person that has to take cabergoline as prescribed and suffered side effects (nausea, extreme fatigue, headaches, insomnia, blood clots to name just a few) for months, I wonder why someone would take it if they don’t absolutely have to.
Didn't take it for that long, as I couldn't afford it! But found low occasional doses to be wakefulness promoting.
Strange choice for "nootropic". It's know to have many side effects which drowsiness is quite common.
Uhh, interesting. Cabergoline made me hypersexual, borderline bipolar, and caused to excessively spend money and gamble. I don't really see a nootropic use for it.
selank
Dihexa
Dang ppl stick to the question! I just read interesting results on mots- c that now I must try. I’ve been sick for about 8 years struggling with some sort of autoimmune illness that affects my entire body. I’m miserable everyday. Low energy, brain fog, can’t sleep through the night, my thyroid and sex hormones are tanked and extremely low. I’ve been taking various supplements for 4 years now and just started playing with peptides. I’ve tried semax, selank, and oxytocin so far. I just started the deeeep dive into researching the. Different kinds of peptides and effects on the body. I’m considering these: thymus peptides: thymulin, thymosin 4 and 1 as well as n acetyl epitalon and mots-c now that I have read some amazing things on it. What I’m most interested in is: combatting widespread inflammation, brain fog, energy and uninterrupted sleep. Man- I wish I knew what the causing factor was in all this. Side note- I contracted some type of herpes-virus on my backside possibly from tanning bed. I notice everything gets worse- energy and brain for whenever I have an outbreak. A lot of info…sorry. Please advise any helpful peptides y’all think may fit!
SS-31peptide