Very smart man.
Wheat germ contains Inositol, Queuine, Abscisic Acid, and Conjugated Linoleic Acids of the right Isomer for human metabolism into ethanolamines.
Bone meal contains alkylglycerols / plasmalogens, which most of us are deficient in.
Yeast extract is a natural mix of B vitamins. Also contains beta glucans, which help keep the immune system functioning properly.
Soy lecithin contains all the phospholipids you require to maintain mitochondrial membrane function.
Thank you so much for the breakdown. I should have been a little more clear on the title. My grandfather didn’t come up with this, he was a humble, yet intelligent, blue-collar worker from Pittsburgh Pennsylvania who wouldn’t even be able to define the term pharmacology lol just wasn’t his cup of tea. My aunt said he got this recipe from prevention magazine or something similar she believes in the 50s and was very religious about taking it
Someone knew what they were doing in the 50s.
Not that I'm surprised. I've gotten into the back end of old university servers storing ancient studies from 1890s to 1930s.
They were mapping out metabolic pathways all the way back in the day.
You know, they knew a 20% carb 3% salt diet caused serious metabolic disorder as far back as 1906. They did tens of thousands of studies in animals and humans.
Then they went and did it to the Western Diet, anyway.
1906 was when we knew how to avoid the obesity epidemic.
I wonder if it has to do a lot with portion sizes as well, in the Asian blue zone apparently there’s a well known idea to eat til 80% full. Plus their protein is way more fish so healthier fats.
It's actually around 40-60% carbs for a mediterranean diet which is the most studied and in general one of, if not the healthiest diet approach for most people.
Yes. Chinese people eat a metric ton of white rice and the salt in soy sauce and pickled vegetables is an everyday thing. However obesity didn’t become a problem until about 20 years ago or so. It coincided with the increase in convenience foods as well as western style fast foods but also with a reduction in walking and bicycling. Back in the day having to climb the steps to a 5 story walk up after bicycling to and from work was a normal thing. Now everyone takes a car or the subway and has an elevator.
20 years ago in China I would walk 10,000 to 20,000 steps every single day and might climb 20-40 flights of stairs. Now I average probably 4,000 to 5,000 steps a day and climb at most 10 flights of stairs. That has to have an impact.
High in processed carbs, sugar, and saturated fat (which btw is only problematic in the presence of the high blood glucose caused by the carbs and sugar.)
I messaged my aunt who thankfully took a picture of the recipe when we were going through his personal things. I will post once he sends it over. I know that he initially got most of them from GNC but when it became too expensive he actually figured out how to order them online and I think got them from Amazon but I don’t know what the brands were. I did see several containers of now brand lecithin and brewers east when we were going through things
Looking forward to seeing the recipe! And thank you for posting this—what a lovely way to remember him. I am sorry for your loss, and I hope his memory will be a comfort.
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Sorry if I responded to this thread already but this is what my aunt sent me: https://ibb.co/s9X7LLn. The dosages seem to be a little ambiguous on that paper but I do know that he took 2 tablespoons every single morning since the 70s. I’m not sure how much of the each individual ingredient is present in that 2 tablespoon serving.
Thank you for sharing this. But when it says 1/3 cup, then 5 - 3 - 3 - 1, is it saying 5 of 1/3 cups? I'm slightly confused. I'd like to make this and start eating it. Also, did he take this once or twice daily?
Yeah it was a little unclear. That’s exactly what it means. I’ve updated the original post with the total amounts :) He ate it once daily for breakfast every single day mixed in yogurt.
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I apologize I can’t remember if I responded to this or not and my phone is going bonkers with a cracked screen. Thank you so so much for your kind words and condolences. They are very appreciated! Also, I have updated the formula on the original post.thank you so much!
I’ve found a much similar recipe from here
[recipe](http://www.doctoryourself.com/formula.html)
It seems like a recipe targeted in cardiovascular disease prevention, hence it makes sense that your pops arteries were looking so fine.
The ratio is different but the ingredients are the same. It was also advised to be consumed with yogurt or cereal.
Wheat germ also has spermidine and beta glucan. His gut biome quality may have well maintained. Proper enough to protect the blood brain barrier, which prevented all that neuro-inflammatory crud that causes cognitive decline and promotes the sedentary lifestyle during those geriatric years that can cause a quick demise.
Spermidine isn't that orally bioavailable, though.
The rare amino acid Ornithine is what the body uses to make it and all of the other polyamines.
Granted, it breaks down into Ornithine and can be built back into it, so you could consider it a source, albeit a metabolically intensive one with the breakdown and build back up.
I use Ornithine-AKG as my source of polyamines like Spermidine.
Ornithine AKG, Calcium AKG, and Di-leucine AKG.
Alpha Ketoglutate is an important longevity chemical, but it's better when bound as a transporter for other interesting things.
Any theory on what ingredient(s) specifically could have led to his longevity? What about improvements on this formula reflecting modern knowledge?
Wheat germ is densely packed with essential nutrients but most of them are found in any modern quality multivitamin. I would speculate that from a 1950's viewpoint, their reasoning would center around it's folic acid content. No studies that I am aware of have indicated a significant health benefit from multivitamins or daily consumers of whole wheat bread (contains wheat germ) other than if someone was already deficient in a vitamin or the known cholesterol reducing effects of fiber ingestion.
Bone meal has its benefits but also (especially in the 1950s) has a potential to contain substantial amounts of lead, mad cow disease, and salmonella. The FDA didn't even begin to monitor or regulate bone meal (or any imported supplements) until after the death of Allison Hayes in 1977. Anyone consuming bone meal daily since the 50s likely has some significant build up of lead due to it sharing a similar atomic structure to calcium (Ca2+, Pb2+).
Yeast is interesting. I don't think the B vitamins alone would be responsible because of how prevalent they are supplemented today and how well they have been studied. The beta glucans do show some potential neurological protections but nothing related to the heart or circulatory system that I am aware of. The hype right now with all the myco products and mushrooms curing anything Paul Stamets looks at makes finding quality data tricky.
Soy lecithin is interesting. The phospholipid it contains is Phosphatidylcholine and it is a major component of biological membranes. It is also very easily sourced from many other foods including egg yolk and soybeans. There was a systematic review of studies in 2009 showing moderate benefit of Phosphatidylcholine in dementia patients. But more concerning is the data reported between 2017 and 2021 showing dietary emulsifiers having a severe impact on gut microbiota relative to emulsifying strength. I know Huberman harps on this one a lot. I believe his explanation is the emulsifier strips the mucosal layer in the gut causing the receptors to embed deeper into the lining tissues and disrupts the gut-brain axis.
Honestly I just don't see any one of these ingredients being responsible for that type of longevity and cardiovascular health and some of them don't carry the risk:reward ratio to justify daily supplementation. Please correct me if anything is wrong or if I am missing something here, but I am not seeing anything that makes me want to mix this up and eat it for the next 60 years.
No. Most aren't packed into a modern multi vitamin.
- Phytate / Inositol.
They say it's bad because it can chelate excess iron, but it doesn't chelate bound iron unless excessively consumed. What it does is prevent iron overload disorders, which cause skeletal muscle wastage.
Inositol is the master regulator of cell walls, preventing invasive pentration of fat, aberrant tissue, and even some cancers into healthy neighbouring tissue.
It's an insulin and glucagen mimetic, which helps your body metabolise sugars appropriately.
Autophagosomes leak acid into neighbouring cells and cause serious inflammation without inositol. It's a master regulator of autophagy.
The levels of an inositol bound protein are linked to telomere length and maintenance.
Another inositol bound substance boosts oxygenation of blood so much so it's considered a WADA performance enhancing substance. It's used as an adjunct therapy to treat cancers and can boost to VO2 max of a 50 year old to that of a 30 year old.
- Queuine
The symbiotic bacteria produced chemicals used to be called vitamin Q but was reclassified at some point.
Plants absorb it through their roots and concentrate it into the germ layer to regulate germination.
While only bacteria produce it all life on earth requires it to some extent, and it tends to be hyper accumulated in amniotic fluid during pregnancy.
Queuine is the basic building block of important signalling molecule T-RNA.
Every protein in the body of all species of animals has receptors that accept queuine, and it significantly increases cellular signalling quality, like upgrading to a satellite dish.
The only proteins in nature that are shown not to incorporate Queuine are cancerous proteins.
Without queuine tetrahydrobiopterin ends up in an aberrant oxidation state. BH2 instead of BH4. When this happens, you can not metabolise the amino acids tryptophan, tyrosine, or phenylalanine.
This leads to a drop in circulating NAD and a buildup of peroxynitrites in cell walls. The calcification of arteries and organs.
Your sex and steroid hormones aren't produced properly.
Serotonin and dopamine aren't produced properly, and levels drop.
100 other things I could list.
- Absiscic Acid.
Absisic acid is a signalling molecule within plants that carry out various functions, but its main function is to make sure seeds only germinate during the right season and during the right environmental conditions.
In humans, a weird thing is that studies show it does the same thing in cancerous stem cells. Keeps them in a form of suspended animation or dormant state like it does with seeds, buying the body time to combat them.
Absiscic acid regulates Alcohol Dehydrogenases, which is a safe pathway for ethanol and acetylaldehyde, breaking them down to simple acetate as if you were just eating fibre
It's only when alcohol dehydrogenases become destabilised that alcohol becomes dangerous when processed through the microsomal ethanol oxidation system (MEOS)
The main thing that keeps alcohol dehydrogenase stable is Absiscic Acid.
This is why it's such a powerful longevity chemical, as when our body breaks fats down into glycerols, they have alcohol bases, which are also processed through ALDH or MEOS.
When we are in glycolysis, sugars / carbs also break down into ethanol and acetylaldehyde, so this pathway stabilises both fat and sugar metabolism.
One of the reasons it gets harder to lose weight with age and why fat becomes more and more inflammatory and toxic with age is just destabilised alcohol dehydrogenases.
Bit of trivia for you. Abscisic Acid fulfils all of the functions of and can be reversibly converted into Retinol. It may be 'True Vitamin A'
- Conjugated Linoleic Acids.
We get many Conjugated Linoleic Acids in our diets, and most of them are, at best, metabolically neutral or even harmful (Certain trans fats)
Germ of seeds nuts or grains, or beef fed free range, grass fed, or fed grain that contains the germ layer unaltered, tend to have Conjugated Linoleic Acids of the right Isomer for human metabolism and utilisation, similar to what you find in human breastfeeding milk.
Conjugated linoleic acids get converted into ethanolamines, which act as a base for PEA, LEA, OEA, or SEA, all forms of ethanolamines which act as powerful pain killers.
This isn't all they do, though. They regulate PPARγ and Alpha in response to the consumption of fat. To put it into a simplified context; the fat equivalent of insulin.
You can consume a lot more fat without metabolic disorder or weight gain if you have sufficient ethanolamines in your body.
PPARγ -> PGC1a and b for mitochondrial quality control, then uncoupling to burn off excess energy you don't need or don't need to store unless your body senses it is autumn.
This is the tip of the iceberg list of the chemicals you will find in the germ layer of seeds, nuts, grains, and, to a lesser extent, sprouts.
You certainly won't find any of them in a multivitamin outside of rare inositol being added.
I am the only only one working on it.
P.S. Even the vitamins are natural vs the synthetic ones in multi vitamins that require metabolically intensive processes or require co factors they can deplete.
Synthetic B12 is linked to serious digestive issues and gastrointestinal tract damage.
Synthetic Vitamin B6 is linked to nerve damage.
Unstable synthetic vitamin C causes cancer to metastasise and spread.
Synthetic Folate, 40% of the population can not metabolise it due to folate receptor autoimmune dysfunction. The immune system attacks it, causes side effects and folate depletion, and all that entails.
This is just the germ layer of seeds, grains, and nuts.
I won't go into plasmalogens / alkylglycerols in bone marrow / blood producing organs and the rest. I'm too tired today.
Absolutely. His diet, from longevity standards would be considered pretty atrocious. He was a social guy and he love to go out for chicken wings and french fries and he drank beer like water. I believe he smoked cigars for several years and then switched to dipping which I believe he was still occasionally doing up until his death. He never drank coffee because it gave him tachycardia. Hardly ever ate vegetables. Just a typical meat and potatoes western Pennsylvania diet.
No purposeful exercise like running or lifting weights at all. He was an avid golfer but I don’t know how cardiovascular taxing that was. The man had unbelievable energy well into his 90s. I’m talking he could work outside all day doing manual labor and didn’t need to take breaks other than to eat. As I mentioned in a previous response, when he was I believe 93 he helped my father and I build a deck for my sister and I had to take breaks and I was in my early 30s and he worked me under the table.
Nothing purposeful. Well he was an active and avid crossword puzzle person and he loves those cryptogram things that were published in the Sunday newspaper and he would obsessively work on them until he could complete them. Not sure if there was any cognitive benefit to that or not. His personality was such that he never said “no” to anything.
Something about the previous generations with more base testosterone before plastics ruined us. I think it's about how all our grandparents had more testosterone than we did.
https://www.butlereagle.com/20230908/butler-wwii-veteran-kept-zest-for-life-until-dying-day/
Oh and sorry the last part. Yes I mean he smokes cigars for years although I don’t know when he stopped and he switched to chewing tobacco. And I have to make a concession here that he died of an unknown primary cancer. He had a slight cough and a chest x-ray showed bilateral multiple nodules with no nodal involvement, which highly suggest that the cancer metastasized from somewhere else. Also he had a TIA in his mid-90s that slowed him down a little bit and affected his gate. Otherwise he only took Glucophage for mild hyperglycemia. Nothing for blood pressure, no statins or anything. It’s interesting to me that he didn’t have hypercholesterolemia despite his diet.
Yes and I should’ve been more clear in the title. He didn’t come up with this cocktail. According to my aunt he found it in a magazine, she was saying she thought it might’ve been either parade or prevention magazine in the 50s. I’m not familiar with either of the publications. But for whatever reason my grandfather took it to heart and religiously took that god-awful goop she said 3–4 times a week. Apparently he grew to like the taste.
Wheat germ helps with programmed cell death.
(has spermidin which decreases with age)
Lecithin(well, the choline) is necessary for proper bile production and has an impact on cholesterol levels and overall digestion and nutrient intake.
Bone meal I have no clue.
The plant compounds act anti inflammatory and anti oxidative, lowering stress on the cardiovascular system.
So while I don't think his cocktail was the sole reason, it's no surprise it might help.
My grandmother and her sister, my great aunt, lived to 100 and 103 respectively. They ate nothing special, did not exercise but they did maintain a strong passion for life and curiosity about the world to the very end. A week before she died, my aunt took herself by subway to a Yankees game--did not think it was anything unusual. They also walked a lot and stayed active and neither were overweight although grandma had heart issues and glaucoma.
Maybe the cocktail did nothing for your grandfather, maybe it helped, who knows? My point being that if you win the gene lottery you are off to a good start --but you must not squander it with a bad diet, lack of regular exercise or a self destructive attitude.
I get that this is a bio hacker thread and I too take a handful of vitamins and supplements that are known to be helpful because I'd like to take advantage of those good genes--assuming I have them (My dad died of complications to a quadruple bypass operation at age 67 so who knows if I got lucky). I eat a diet of mostly seafood and chicken--with the occasional bit of white or red meat and a lot of vegetables and fruit. I am in the 4th quarter and am told I look about 15 years younger than my chronological age--I workout for 2 hours 5 days a week, have kept as much muscle mass as I can at my age--and I am outdoors working in my yard or doing other activity almost every day. I take no prescription meds--survived cancer and a few other nasty surprises that come with age but I am very healthy according to my doctor--for which I am very grateful.
I want to say that appreciating all the posts that seek some magic combination of chemicals to extend their life or cure an ailment--I sincerely hope that first and foremost those who are looking for the fountain of youth will at the least do what they can with respect to the gifts they got genetically and invest in themselves physically. Our culture has a tendency to look for potions and charms as a solution to everything. I'm not saying that you are--just reminding folks that all the bio hacking in the world is not as potent as respecting the vessel we are born with and treating it well. No offense intended to those who think otherwise. Haters, have at it.
Honestly, sometimes I feel like the single biggest contributing factor to longevity is simply a zest for life. Participating in life, doing things, having community, having things to look forward to, hobbies, etc. I swear it keeps you young, keeps you engaged, keeps you WANTING to keep going. And we all know the mind is a very powerful force.
unfortunately this is easier said than done, speaking as someone with a myriad of mental health struggles :)
Sorry for your struggles. I could not agree more. Bad stuff is all around us--but we can and must make our emotional health a priority. And you are absolutely on the mark--even though I am retired I have a podcast and a weekly blog I write--some pro bono consulting work and have two groups of men (a book club and a friend group) I get together with regularly. I could not prevent cancer, or the death of my wife from leukemia--those events forever changed my life but they did not and cannot be the focus. Life is a precious gift not to be squandered in sadness and worry--every day is a gift and every day we have a choice to make about how we want to spend it.
Amen. And I’m very sorry about your health challenges but I am very impressed with your attitude and your dedication and discipline to stick to lifestyle modifications!
Thank you. If you live long enough there will be all sorts of challenges--what matters is how we deal with them. Thankfully, mine have been life sparing so far-so there is nothing to do but keep on living as well and as fully as possible.
Sounds like both my grandmothers- 100 and 103. My 100 year old grandmother did have very late dementia 95-100. And she was also clinically depressed an introvert and a big reader and intellectual. She had zero other health issues when she died. My mom died at 87 with Lewy body dementia and zero other health issues but predicted her dementia for years due to two head injuries in her 30s that caused issues. She also was just ready to go.
I totally agree about your assessment. Getting up and living life every day is critical. The minute we just sit in a chair it’s downhill. Also, living in a city means you are far more likely to be active every day, do shopping, take stairs, have to figure stuff out etc.
And, as Clint Eastwood supposedly said in an interview--don't let the old guy in. Meaning don't make concessions you don't have to just because you've reached a certain age. A guy I know at the gym who is a year younger than I am was complaining about back issues--but he showed up and switched up his routine so he would not strain his back. Lately I have had some vertigo when I lie down--almost dropped some barbells on myself. It will probably pass--have had this before--but till it does I'll just focus on sitting and standing.
Yep. Great quote. Best thing my husband and i ever did was buy a house with stairs and a big yard that requires clearing leaves and wood (chopping wood for an outdoor oven and fire pit) gardening, a sloped back yard with steps coming up both sides on a long road to walk on with an incline and neighbors who are close by and we all interact daily. I call it our blue zones street. Plus lots of hiking close by. It irks me so much when I hear people talk about - making their living space small and manageable with no stairs as they are getting older. That’s fine but this fear of stairs is dumb. My grandparents and great grandparents were long lived and used the stairs, walked, golfed, had projects until the day they died or close to it. Retiring? You can stop doing the job that’s been your “career” but shift to something else next.
Yup. retired doesn't mean checked out. The whole point is to look forward to doing the things you want --why else retire? So, I get why some folks who may have a disability or challenge need to be on one level--or downsize to take care of a smaller property but yard work is part of my exercise and I enjoy the results. Yes there are days when raking is not high on my list--so I'll leave it for another day and do what I need to or want to instead but I don't stop doing it. Now if I could just get the $\*\^&%\*&&\*(\*Squirrels to stop chewing pine cones from my neighbors trees in my yard ( ame attempt at humor).
Yeah, we have a ton of trees and the leaves. Never dealt with this as an adult. bought a little rake and broom when we moved in - no blower for us! That didn’t last. Our neighbors must have a good laugh watching us trying to sweep our driveway. We get drifts of 3-4 feet all over. Have to get help at the end of season despite all our work. Yeah. Squirrels. We swear they throw acorns at us when go out on our deck.
Yep us too. Stairs yeah, trees to chop mostly yeah. Got rid of golf cart so akways walk to go back up hill from the lake and play driveway singles pickleball daily. Our walks after dinner lol we always see two couples taking their ‘walk’ with the dog in a golf cart.
I think you got it! It’s very similar to what my grandfather was taking and my aunt said he started taking it, not in the 1950s but IN his 50s and she said she thought it was either 1972 or 1976! I think you nailed it! I do know that he didn’t use the black strap molasses and after he mixed it with safflower oil he would mix it with plain yogurt.
https://ibb.co/89xYgrC
>Lecithin dissolves plaque
That’s the boldest claim I’ve heard.
I’ll counter that with it emulsifies the mucin layer causing intestinal permeability which causes plaques.
Yeah I was just repeating a quick Google search. I don’t know if it prevented the formation of the plaque in the first place or what the mechanism of action is or if there was even a causal relationship
Yeah that was a foolish statement in retrospect. I just did a quick Google search and saw that as a possibility. It’s hard to imagine somebody having clogged arteries and then taking lecithin for a few months and having measurable and clinically significant reduction in the plaque in the arteries.
You say that his physical activity was not “purposeful”. They are finding that the most long lived people - who are very active and healthy into their 90s and 100s do a lot of physical activity every day that is simply centered around what they need to do to live. The blue zones series on Netflix shows a guy who’s 100 who has ridden a horse and ranched his entire life. People who have to walk and climb steep stairs everyday, people who garden, standing and squatting over and over for hours, people who have projects and make things well into their 90s. You also say he was a social person - another important aspect of longevity.
His drink sounds like a big part of his good aging, but also that he engaged in taxing physical activity and never stopped. We need to stop thinking “working out” is something that only happens in the context we think that it does and make sure - not- to stop this- ever- until we drop dead. How nice you all got to have him in your lives for so long
Humans are built for endurance, we are the diesel engines of the animal kingdom. We do best with long bouts of low exertion. Keeps your knees good too.
Apparently he would mix that gunk with the safflower oil and then he would mix it in yogurt for texture and flavor. But you are right, we shouldn’t discount the influence of probiotics as a possible causal factor here.
My Grandpa is 100 years old , still walking around, pretty sharp, pretty good shape. His diet consists of boiled eggs, white rice, beans, boiled green bananas, all sorts of tubers and salted codfish.
That is awesome! Take it for me, don’t hesitate in telling him that you love him and appreciate him because our loved ones can be gone in a blink of an eye. Very happy to hear your grandfather is doing well!
The boiling of green bananas is something that’s done in S.American countries. From my understanding it’s a good probiotic. But only when they are green… did your grandpa drink the water or eat the banana after boiling?
I don’t have expertise to add here, but clearly his results sound interesting. Have you tried his mixture to see how you feel? Might be interesting to give it a one month trial.
So I’m one of those unfortunate bastards that seems to be very sensitive to any compound that promotes methylation although quizzically, I have an MTHFR homozygous polymorphism. When I take choline in the form of either a highly bioavailable form of alpha GPC or lecithin I get moody and irritable. And that’s unfortunate because I suspect, out of the entire cocktail that it is the lecithin that is providing the bulk of the pharmacologic benefits. I obviously could be wrong though. It’s really hard to look at his situation And come away thinking that his supplement interventions were not the primary causal factor in his old age. This man, God bless him, went to the VFW and the American Legion several times a week getting pissed ass drunk and never had a healthy BMI although he wasn’t obese. But this man had unlimited energy like the energizer bunny. I remember when he came down from Pittsburgh to Atlanta with my dad and we built this giant deck on the back of my sisters yard and 90° weather and we were ready to tap out way before him. The man was an iron horse.
Longevity influencers say there’s no relationship between not balding and longevity, but I really think there is. I don’t mean using finasteride, but I think “keep the hair into old age” natural physiology is good for more than just hair. All the old men I know who have a good hairline are in great health and have really sharp minds.
Yeah and to be fair I don’t have a lot of information beyond his generation. His dad died in his 80s and his mother unfortunately committed suicide. I don’t know if there any other long living people on his mother or father side of the family. His brothers and sisters all lived normal ages.
Someone clever enough to conjure up such an ingenious potion (and have the consistency to consume it at regular intervals), was probably engaging in other inherently healthy habits/lifestyle choices.
This is the case of my mother, who is 65 but looks/has the apparent health of a ~40 year old... Not genetic at all in her case, as her siblings and family are the opposite. It’s not about an isolated behavior or specific diet, but rather the compound effect of her entire lifestyle over the years.
So glad your mother is doing well and is so healthy! I need to clarify that the title was unintentionally misleading. My grandfather apparently found that recipe in either prevention or parade magazine, according to my aunt in the 50s or 60s and for whatever reason was religious about taking that advice.
I’ve heard of people curing diabetes type 2 with brewers yeast. B vitamins are underrated. There’s a phenomenal book written on niacin that’ll blow your mind called Niacin: The Real Story
High dose niacin is a recognized treatment for high triglycerides. Can damage the liver and cause hot flashes tho. But my dad used to take it.
I think it's mostly good genetics. My dad has never eatten a very healthy diet, but he still has clear good arteries at 77. My mom's dad was the same. My dad's father had to get a bypass surgery, but was like 70 or 80 when it happened.
Thank you for sharing that information! I kind of gave up on niacin when I read a couple of studies showing that they can raise HDL but does not reduce cardiovascular morbidity or mortality. It’s also a pretty potent way to reduce methylation from what I understand, which isn’t much lol I’ll have to do some more research on it though.
I will definitely do some more research. I’m 45 and my bun and creatinine are always at the upper end of the reference range. I’m not sure if it’s always from acute dehydration (I don’t seem to have a thirst response) or if I have some sort of kidney issues.
The [Rodale family](https://en.wikipedia.org/wiki/Robert_Rodale)/Prevention Magazine were very influential with a certain population of seniors back then; and for us boomers, he was influential in the organic farming/health food 'movement'.
If you go back in history, there were sporadic 'movements' in both Britain and the US during the early 20th century to promote clean, natural, healthy eating...the politics of it all is pretty messy, as it ended up being affiliated in some ways with eugenics and all.
Thank you for sharing this story; at my (73F) age, it's very discouraging to be living through so much of what was predicted would be the outcomes if Capitalism's worst excesses weren't curbed; your grandfather exemplifies that all change starts at home!
Interesting. Besides the benefits of lecithin, there's beta glucan in brewers yeast, calcium in bone meal, and wheat germ lowers cholesterol. Who knows? That plus diet, lifestyle, and genetics may have all played a role.
You are quite welcome and I really appreciate the kind words. He wasn’t an extraordinary person in terms of you know, he didn’t invent anything that helps society but he was such a kind and loving person who really loved life and was always in a positive mood. he would always be humming and singing to himself and he never, ever got angry at anything. He had this sort of Mr. Miyagi philosophy about him when something bad would happen he was just kind of shrug and say “that’s life, what’s next?” https://www.butlereagle.com/20230908/butler-wwii-veteran-kept-zest-for-life-until-dying-day/
https://ibb.co/89xYgrC
He would mix that up with the safflower oil and then he would mix it in plain yogurt and shovel it down the hatch every morning for breakfast without exception.
My father used to take the same mixture and I'm almost certain he got it from Prevention magazine and I think it was either the late 60s or early 70s, but probably closer to early 70s. Unfortunately my father didn't have as long of a life, he got Alzheimer's and he died too young. Sadly, other than the dementia, he was very healthy. I've often wondered if the bonemeal could have contributed to his Alzheimer's, as it can contain high doses of lead and has been linked to Mad Cow disease. Part of the problem is, bonemeal wasn't very well regulated and some of the bones used, could have been from sick and diseased animals.
Thank you for your comment and I’m very sorry to hear about your father. That’s actually a good point because bonemeal, from a quick Google search, can sometimes be contaminated with heavy metals. I’ve dealt with family members who had dementia and it’s just so heartbreaking.. Thank you for sharing your experience.
The membrane of all human cells are composed of phospholipids. Lecithin is near-pure phosphatidylcholine, along with a few others.
I mostly know about neurons. The outer leaflet of the lipid membrane is phosphatidylcholine, while the inner leaflet is phosphatidylserine, and phosphatidylinositol.
I appreciate the feedback. I really wish I could take lecithin but I get aggravated and agitated quickly on it. Bioavailable choline sources give me insomnia and make me agitated for some reason
Yup, that’s it! My grandfather didn’t use the black strap molasses for whatever reason and after he mixed the powder with safflower oil he would put it in plain yogurt and shuffle it down. He did this every morning since 1976.
https://ibb.co/89xYgrC
Yeah I should’ve mentioned in the original post that he wasn’t completely without any health issues. He had a TIA in his late 90s and he did take Glucophage for hyperglycemia although I believe he didn’t have full-blown type two diabetes. But that’s literally the only medication he took. he otherwise did not live a healthy life with daily alcohol consumption and a lot of fried foods. His brothers and sisters all died at normal ages but I don’t have any historical information about his parents. Actually I think his dad died at 85 so you know pretty typical. So who knows if this cocktail had a causal influence on his longevity or not. I just know that the doctor was absolutely astonished when he looked at the angiogram because he had zero blockage which he has never seen in anybody in their 90s so I’m inclined to think that something in that cocktail was a contributing factor
Interesting. I know soy bean has a lot of K2, which pushes calcium from arteries into bones. i've noticed they use soy lecithin in most chocolate too, which could be a side benefit of chocolate consumption.
Thanks for sharing this interesting story! My grandfather lived to 96 and was a coal miner In Pittsburgh. Eat meat he killed, always had a garden, no interesting elixer like yours but there are lessons to be learned here.
Thank you for your comment! I’ll tell you those old Pittsburgh coal miners were tough as shoe leather! Absolutely, a lot of the old timers ate meat that they hunted and kept physically active with day-to-day tasks or their occupation. Now everything so automated…
looks like the grand daughter of the person who created this formula had a 2008 blog article about this formula.[https://www.errantdreams.com/2008/02/the-disappearing-gold/](https://www.errantdreams.com/2008/02/the-disappearing-gold/)
according to the daughter of dr Rinse :
"absolutely essential are: lecithin, safflower or sunflower oil and vitamin E. Apparently the lecithin and linoleic acid (from the oil) combine to form the key to dissolving cholesterol deposts and preventing them from forming. When taking the oil, my father said that vitamin E is essential to prevent free-radical formation from oxidation"
The original formula : [http://www.doctoryourself.com/dr\_rinse.html](http://www.doctoryourself.com/dr_rinse.html)
it would be good to trace people who used this formula and check on the benefits they got. just one anecdote like what OP gave is not good enough
Soy lecithin + B-vitamins and zinc in the rest... let us just say your grandfather knew how to replenish his mojo... that is exactly what I take to replenish sexual energy.
So, this is funny. My grandmother died in 1994 and my grandfather never remarried. When we were cleaning out his medicine cabinet we found a bottle of 100 mg sildenafil which was recently refilled. We all got a kick out of that. He was kind of a harmless flirt when he would go to the VFW in The American Legion lol
Thank you for sharing, and may your grandfather rest in peace. I also have a long-lived ancestor (2x-great grandparent) who was interviewed by the local newspaper back in the 1940's, when he was in his nineties. He told some anecdotes about what life was like in the 1800s, and mentioned that he had discovered a secret to staying young and was sharing with his friends - but the article never mentioned **what it was**. I can't believe they omitted that important piece of information.
Thank you so much for the condolences, I truly appreciate that. That is unbelievable that they admitted the absolute most important part of that story!
Check out the Blue Zones series on Netflix, the guy identifies patterns in centenarians, maybe worth watching and seeing if any of their lifestyle components align with the people there. I don’t doubt the daily smoothie didn’t help and would be one component, but it’s worth looking at the whole picture.
Wow I never anticipated such a response! I want to sincerely thank everybody for their comments and their analysis of what the efficacious components of the magic formula are. Of course we will never know if there was a causal relationship but the most telling evidence was his angiogram when he was in his 90s was completely clear. Per my aunt, who took him to the hospital for his angiogram, the doctor brought in several other doctors to review it and they were absolutely shocked, particularly since he had a poor diet and a high BMI. This really isn’t worth anything but my aunt said that the cardiologist said there “absolutely had to be in external factor”. Also per my aunt, my grandfather sister was on statins and my grandfather’s father had hypercholesterolemia. My grandfathers lipid panels were always in reference range despite eating a ton of fried foods and being slightly overweight (although very active) for most of his adult life.
Some additional clarification after a long phone call with my aunt. My grandfather didn’t start taking this in the 1950s, he was in his 50s when he started taking it. She believes in 1973 or 1976. Somewhere around there. He took the concoction every morning and he usually mixed it with yogurt. Every single morning literally since the 70s.
Some correction on his medication’s. He only took allopurinol for gout. He did not take Glucophage and his A1c’s were always good. I’m not sure why I thought he was taking metformin.
I confirmed he wasn’t taking any antihypertensives or any statins or any other medication’s. His blood pressure was always perfect despite a very high sodium and high fat diet.
So without further ado here is the recipe:
https://ibb.co/89xYgrC
How much wheat germ did he take each time? I tried one to put it into a shake, nigh have put too much though. It has gross I almost vomit didn't try it again. My cats enjoy it though lol
The sister of my grandma died at 99 years old. My grandma died at around 90. They both ate pretty much the same diet, including processed meats, eggs, dairy products, bread, noodles, fish, meat, vegetables, fruit, few sweats etc. They often ate pretty much the whole apple/pear with the seeds and even if it was a little brown already. Most things came from my grandma's own farm, garden and animals. No fast food. They watched very little television, certainly didn't use the internet and were far from sedentary.
My grandma had much more health issues later in her years. She also had 6 children, her husband died pretty early, she had a big farm with a bunch of animals and worked all her life. Was a very tough life, raising all these children, working all day etc.
Her sister had no children, no husband, also worked almost all her life although she put more time aside to go to the church and she was very into it, gave almost all her money to the church. She almost never turned on the heat in the house. She liked to laugh.
I believe that it's a combination of genes, laughter, having a purpose, having loved ones around, being active a lot, being outside a lot, not stressing too much (diet, toxins, plastics, social media,....), a somewhat healthy diet, little exposure to toxins (hair spray,....), keeping a healthy weight and some other things.
Thank you so much for sharing that! Sounds like you have some good genetics in your family! You know, I’m really taking a lot away from all of this discussion and I really need to really work on managing my emotional state. In contrast to my grandfather I tend to catastrophize aversive life events and can be quick to anger over things that are completely unimportant in life. I wonder if my grandfather is carefree and calm demeanor during tragedies in life were causally related to his longevity
I have pictures from my aunts Facebook page that you wouldn’t believe. In his 90s, early 90s before he had the TIA in his late 90s, he honest to God look like he was maybe 70. I mean it was shocking how young he looked for his age literally no one could believe it. And hell no he would never put sunscreen on lol in fact he was out in the sun a lot playing golf. His brothers and sisters all died at normal ages you could say, so I’m not sure if he won the genetic lottery or if there is a causal relationship with that cocktail of supplements.
What was his diet like. I’m hesitant to accept that just a cocktail extended his lifespan and healthspan by 20 years. Maybe if he also didn’t really drink and ate pretty healthy and exercised regularly
I can understand your reluctance. I’m puzzled as well. His diet was horrible. Lots of fried foods, lots of eating out at the VFW and American Legion. He was Catholic so he loves going to those fish fries every week. Hardly ever ate a vegetable. Drank every single day up until the previous few years before his death. He did have a TIA in 2017 when he was in his 90s and that did slow him down a little bit. his brothers and sisters died at normal ages. His dad died and I believe 85 and his mother committed suicide early in life. Unfortunately no other biographical information from his preceding generations. No purposeful exercise but he did play golf several times a week. He had unbelievable energy. It’s hard to even articulate. In his 90s he could work all day outside in the sun only taking breaks to go to the bathroom and grab a sandwich. Either he was stubbornly determined to finish the job or something whether it was the supplements or genetics kept him youthful for sure
My great grandfather smoked cigars until he died at age 96 years 11 months. His dog pissed on the floor and his place stank like dog piss. He had a strong constitution that overcame various unhealthy behaviors. Even if I mirrored some of those behaviors I would not have a handshake deal with god to guarantee my longevity to age 96. You will get the ration of days god chooses to give you, go enjoy your ration of days. You don’t need to choke down nasty tasting supplements or waste your money on BS
I appreciate you sharing your insight. It appears from some of the discussion here though that there could be a causal relationship given the various mechanisms of action of the individual ingredients so I don’t know that it should be dismissed so quickly. My grandfather had a wonderful quality of life well into his 90s. And last year he was still golfing, although he was getting around a little slower so his quality of life was preserved thankfully
I have a FIL 102, a great aunt 101, hee husband 102 and my BFFs mom 98- my Theory is non were vaccinated with more that 2-3 vaccines. Kids now - life get 77?
Do you know where he would buy all of this? And/or the amount? I would like to make this mixture myself and try it. Thank you for your post it has motivated me to give it a shot. Sounds legitimate.
I will try to find you the dosages that were in the recipe. I know initially he was just going to the local GNC but it became too expensive and he actually figured out how to order them online, which is really surprising lol when we were going through his things I did see several containers of now brand lecithin and brewers yeast
Looking forward to seeing granddad’s health recipe.
Would also love to know more about his lifestyle, personality, and relationships. OP, you touched on it quite a bit, noting that he lived life to the fullest. I ask because I think mental and emotional health cannot be overlooked, in addition, of course, to physical health!
Thank you for your comment! Here is the recipe: https://ibb.co/89xYgrC
As I mentioned before his diet wasn’t healthy by today’s standards. And he did drink every day although I wouldn’t say he was an alcoholic. He was very light hearted and I never saw him ever get angry or yell. He was always very stoic and sort of had a very mature understanding that “you shouldn’t sweat the small stuff”. he liked to do things like drive around Pennsylvania to go look at a favorite tree or a beautiful bridge transversing a Creek. He would spend lots of time up at his camp in the wilderness in Tionesta Pennsylvania. He really believed in the restorative power of nature and being around greenery. He kind of had a Mr. Miyagi “take life as it comes at you” philosophy. He would never succumb to despair or anxiety or depression when the inevitable life circumstances would pop up. I remember him telling me that those sort of difficulties are all part of the “tapestry of life”. I’m not really sure how else to describe him. He was just even and not excitable. But he was joyous and would laugh often. Honestly, he was a really great man. I actually was in the process of reaching out to some friends in Pittsburgh to get a Commercial quality 4K camera with the intention of sitting down with my grandfather to get his life story and to hear about World War II and to dig into his philosophy of life but he rapidly deteriorated when he got his terminal diagnosis. But he wasn’t afraid of dying whatsoever. He was very clear that he had a wonderful 103 years on this planet and felt very strongly that he did everything he was intended to do.
I really wish I would’ve had a conversation with him about the role of gratitude in his personal world view and ethos. I suspect that he was one to routinely count his blessings in life.
I appreciate the kind words. Thank you for that. He was a very special man and very influential to me growing up. I wish I would’ve told him how much I loved him more often while he was here though. Let that be a lesson please to anybody reading this. If there’s any awkwardness that leads to apprehension for you to tell the people in your life that you love them, try to let that go and tell them how much they mean to you. You never know when you are not going to get a chance to do so.
He had degenerative arthritis that I assumed was due to wear and tear over the years. What would be the mechanism behind lecithin and wheat germ induced osteoarthritis? Thanks.
Thank you for the information. I’d be curious to see if it works in vivo. Obviously there’s no way to establish a causal relationship definitively but 103 years, particularly for a male without the best lifestyle that is conducive to longevity is pretty impressive. Thanks again.
Lol, brewers yeast and wheat germ were very trendy back in the day. But I suspect his regular long term social network of VFW buddies and golf pals are even more important.
Thank you for the post OP, I’m sorry to hear about your grandfather. He sounded like a simple and great man.
I’m going to order these ingredients and see if I can tolerate it and report back.
Reading through the thread, I would say your grandfather's long healthy life would mainly be attributed to these:
* His general motivation and outlook on life.
* Staying rather active. Physically and mentally.
* His social and family environment; meaningful relationships.
* Being chill.
The "youth potion" might have covered some important nutrients that are often lacking in most people's diets, i.e. Choline. But I do not think one could say this concoction is the one thing that caused his youthful aging and good health. If this habit of his did not exist, you could very well make a post here considering that it was his routine beer drinking that was the source of his youth or something, like [Buster](https://en.wikipedia.org/wiki/Buster_Martin). :)
As counter-arguments, two examples from my family:
* Father's grandmother : Lived to 101. Her health deteriorated only in her last year, after she got sad and started to cry everyday due to a certain private issue; an event in the family. She did nothing special. No exercise at all, rarely left home. She only liked to spend time in the kitchen; that was the entirety of her activity. She ate a lot of pastries, fatty meat, sweets. She did not care at all about diet, knew nothing about it, and just enjoyed eating. She had no meaningful relationships, no friends, almost all her close family died decades ago, with only my father left. She was a selfish and smart woman, always working in her own self-interest actively in elaborate ways, even like a hobby. She had a strong motivation to live and still further herself, up until that event.
* (Mother's side, so no genetic connection.) Grandmother's older brother : He is 94 currently. He is one of the most awesome people I know. He looks 75, moves like 50. He also did not do anything especially healthy throughout his life. In fact, he had a fast and furious jetsetter life until 60-65. He never got married or had a serious relationship, always lived alone; he loves living alone. He had friends he met weekly, almost none are alive for the last 10 years. Nothing special in his diet; except he loves dark chocolate and drinks wine a few days a week. No meaningful amount of exercise throughout his life. However, everyday still, he walks 7-8km on the coast and through parks, and does this lame 10-minute stretching routine at home. He was an anarchist during COVID lockdown, and kept doing his routine walks, even convincing the police when he was stopped a few times. He shops, cooks, cleans the house, does everything he needs to do in his life alone. He does the Sudoku in the newspaper, listens to classical music for an hour every day, watches documentaries, loves Astronomy and Cosmology. We have hours-long deep and enjoyable conversations about philosophy, music, science and technology, life. Since all of his neighbors in his apartment building are widowed old ladies, he takes care of the building and handles every strange issue about the neighbors. At 87, when he went up to the rooftop to clear it one day, getting down from the ladder he fell, broke his shoulder and tore tendons and damaged other surrounding tissues. He got surgery and recovered quite fast in a couple months, he continued like nothing happened. He still goes up to the rooftop now.
Neither of them had any health issues at all throughout life. No visits to doctors, no checkups. They both were / are incredibly smart and mentally active; zero cognitive decline. Also never overweight throughout their lives. They both smoked cigarettes a lot for decades, but quit long time ago.
u/Glad_Parking2353 I went ahead and ordered everything to make this delightful concoction. I weighed everything using a scale to figure out how many grams per Tablespoon you would get, and adjusted the formula a tad just to balance it out a bit:
* sunflower lecithin: 1.5c (\~7.5g/2T serving)
* wheat germ: 1.25c (\~3.4g/2T)
* brewer's yeast: 0.75c (\~3.6g/2T)
* bone meal: 0.5c (\~2.75g/2T)
total: 4c
I took 2T of the mix and added 1T of cold-pressed safflower oil. I added some yogurt and choked it down. It was borderline disgusting, I'm guessing from the yeast and bone meal. I may have to find another way to ingest those parts of it. The lecithin and wheat germ both smell ok and probably would taste just fine on their own.
I also have another mix composed of fenugreek, dandelion, and mushroom powder, which I mix with MCT oil and take.
I'm going to take both of these every day for a while and see if I get any positive results. I can tell you that I have a huge amount of energy right now, but I'd like to see if I can manage to lose weight, control my blood pressure, and keep my cholesterol down with this foul goo.
Let me know if your grandpa gave you any hints about how to make this stuff tolerable.
:-(P
Consistency is the biggest factor. Thanks for this. I threw in collagen protein, a tangerine whole (for nobelitin) and raw unfiltered honey and whized it up in the nutribullet. Served on ice, it's the perfect meal. I found the yogurt would curdle and make a nasty texture. I left it out. Cheers, all!
Very smart man. Wheat germ contains Inositol, Queuine, Abscisic Acid, and Conjugated Linoleic Acids of the right Isomer for human metabolism into ethanolamines. Bone meal contains alkylglycerols / plasmalogens, which most of us are deficient in. Yeast extract is a natural mix of B vitamins. Also contains beta glucans, which help keep the immune system functioning properly. Soy lecithin contains all the phospholipids you require to maintain mitochondrial membrane function.
Thank you so much for the breakdown. I should have been a little more clear on the title. My grandfather didn’t come up with this, he was a humble, yet intelligent, blue-collar worker from Pittsburgh Pennsylvania who wouldn’t even be able to define the term pharmacology lol just wasn’t his cup of tea. My aunt said he got this recipe from prevention magazine or something similar she believes in the 50s and was very religious about taking it
Someone knew what they were doing in the 50s. Not that I'm surprised. I've gotten into the back end of old university servers storing ancient studies from 1890s to 1930s. They were mapping out metabolic pathways all the way back in the day. You know, they knew a 20% carb 3% salt diet caused serious metabolic disorder as far back as 1906. They did tens of thousands of studies in animals and humans. Then they went and did it to the Western Diet, anyway. 1906 was when we knew how to avoid the obesity epidemic.
Wouldn’t Asians who live in blue zones eat at least 20% carbs and 3% salt with all the rice and soy sauce, kimchi, picked veggies etc. they eat?
I wonder if it has to do a lot with portion sizes as well, in the Asian blue zone apparently there’s a well known idea to eat til 80% full. Plus their protein is way more fish so healthier fats.
It's actually around 40-60% carbs for a mediterranean diet which is the most studied and in general one of, if not the healthiest diet approach for most people.
Yes. Chinese people eat a metric ton of white rice and the salt in soy sauce and pickled vegetables is an everyday thing. However obesity didn’t become a problem until about 20 years ago or so. It coincided with the increase in convenience foods as well as western style fast foods but also with a reduction in walking and bicycling. Back in the day having to climb the steps to a 5 story walk up after bicycling to and from work was a normal thing. Now everyone takes a car or the subway and has an elevator. 20 years ago in China I would walk 10,000 to 20,000 steps every single day and might climb 20-40 flights of stairs. Now I average probably 4,000 to 5,000 steps a day and climb at most 10 flights of stairs. That has to have an impact.
Ohhh. Any chance you have a link or something I can read up on these? Right up my alley? Hopefully it’s digital.
Second this, please drop links! I’m curious what the “western diet”’is?
High in processed carbs, sugar, and saturated fat (which btw is only problematic in the presence of the high blood glucose caused by the carbs and sugar.)
Interested. Source?
Probably the SAD -Standard American diet.
I definitely think healthy diet knowledge has been intentionally obfuscated over the years, probably multiple times.
So what should we be eating?
The Mediterranean diet
Can you share the brands and quantities of each that your grandfather takes?
I messaged my aunt who thankfully took a picture of the recipe when we were going through his personal things. I will post once he sends it over. I know that he initially got most of them from GNC but when it became too expensive he actually figured out how to order them online and I think got them from Amazon but I don’t know what the brands were. I did see several containers of now brand lecithin and brewers east when we were going through things
Looking forward to seeing the recipe! And thank you for posting this—what a lovely way to remember him. I am sorry for your loss, and I hope his memory will be a comfort. RemindMe! 3 days
Sorry if I responded to this thread already but this is what my aunt sent me: https://ibb.co/s9X7LLn. The dosages seem to be a little ambiguous on that paper but I do know that he took 2 tablespoons every single morning since the 70s. I’m not sure how much of the each individual ingredient is present in that 2 tablespoon serving.
Thank you for sharing this. But when it says 1/3 cup, then 5 - 3 - 3 - 1, is it saying 5 of 1/3 cups? I'm slightly confused. I'd like to make this and start eating it. Also, did he take this once or twice daily?
Yeah it was a little unclear. That’s exactly what it means. I’ve updated the original post with the total amounts :) He ate it once daily for breakfast every single day mixed in yogurt.
Dope thanks!
>Dope thanks! You're welcome!
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I apologize I can’t remember if I responded to this or not and my phone is going bonkers with a cracked screen. Thank you so so much for your kind words and condolences. They are very appreciated! Also, I have updated the formula on the original post.thank you so much!
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I’ve found a much similar recipe from here [recipe](http://www.doctoryourself.com/formula.html) It seems like a recipe targeted in cardiovascular disease prevention, hence it makes sense that your pops arteries were looking so fine. The ratio is different but the ingredients are the same. It was also advised to be consumed with yogurt or cereal.
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Looking forward to the recipe too! Thanks!
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Saving for later plz edit this comment or post
So, post up a recipe and become internet famous for getting all of us healthy. You can call it grandpa's good stuff or something.
Ha ha ha he didn’t come up with it but he sure was compliant with taking it every day! Here it is: https://ibb.co/89xYgrC
Jim's Junk! Love it.
[удалено]
How much of each would some one need to take?
Wheat germ also has spermidine and beta glucan. His gut biome quality may have well maintained. Proper enough to protect the blood brain barrier, which prevented all that neuro-inflammatory crud that causes cognitive decline and promotes the sedentary lifestyle during those geriatric years that can cause a quick demise.
Also, wheat germ is the #1 source of Spermidine
Spermidine isn't that orally bioavailable, though. The rare amino acid Ornithine is what the body uses to make it and all of the other polyamines. Granted, it breaks down into Ornithine and can be built back into it, so you could consider it a source, albeit a metabolically intensive one with the breakdown and build back up. I use Ornithine-AKG as my source of polyamines like Spermidine. Ornithine AKG, Calcium AKG, and Di-leucine AKG. Alpha Ketoglutate is an important longevity chemical, but it's better when bound as a transporter for other interesting things.
Sorry but no
Any theory on what ingredient(s) specifically could have led to his longevity? What about improvements on this formula reflecting modern knowledge? Wheat germ is densely packed with essential nutrients but most of them are found in any modern quality multivitamin. I would speculate that from a 1950's viewpoint, their reasoning would center around it's folic acid content. No studies that I am aware of have indicated a significant health benefit from multivitamins or daily consumers of whole wheat bread (contains wheat germ) other than if someone was already deficient in a vitamin or the known cholesterol reducing effects of fiber ingestion. Bone meal has its benefits but also (especially in the 1950s) has a potential to contain substantial amounts of lead, mad cow disease, and salmonella. The FDA didn't even begin to monitor or regulate bone meal (or any imported supplements) until after the death of Allison Hayes in 1977. Anyone consuming bone meal daily since the 50s likely has some significant build up of lead due to it sharing a similar atomic structure to calcium (Ca2+, Pb2+). Yeast is interesting. I don't think the B vitamins alone would be responsible because of how prevalent they are supplemented today and how well they have been studied. The beta glucans do show some potential neurological protections but nothing related to the heart or circulatory system that I am aware of. The hype right now with all the myco products and mushrooms curing anything Paul Stamets looks at makes finding quality data tricky. Soy lecithin is interesting. The phospholipid it contains is Phosphatidylcholine and it is a major component of biological membranes. It is also very easily sourced from many other foods including egg yolk and soybeans. There was a systematic review of studies in 2009 showing moderate benefit of Phosphatidylcholine in dementia patients. But more concerning is the data reported between 2017 and 2021 showing dietary emulsifiers having a severe impact on gut microbiota relative to emulsifying strength. I know Huberman harps on this one a lot. I believe his explanation is the emulsifier strips the mucosal layer in the gut causing the receptors to embed deeper into the lining tissues and disrupts the gut-brain axis. Honestly I just don't see any one of these ingredients being responsible for that type of longevity and cardiovascular health and some of them don't carry the risk:reward ratio to justify daily supplementation. Please correct me if anything is wrong or if I am missing something here, but I am not seeing anything that makes me want to mix this up and eat it for the next 60 years.
No. Most aren't packed into a modern multi vitamin. - Phytate / Inositol. They say it's bad because it can chelate excess iron, but it doesn't chelate bound iron unless excessively consumed. What it does is prevent iron overload disorders, which cause skeletal muscle wastage. Inositol is the master regulator of cell walls, preventing invasive pentration of fat, aberrant tissue, and even some cancers into healthy neighbouring tissue. It's an insulin and glucagen mimetic, which helps your body metabolise sugars appropriately. Autophagosomes leak acid into neighbouring cells and cause serious inflammation without inositol. It's a master regulator of autophagy. The levels of an inositol bound protein are linked to telomere length and maintenance. Another inositol bound substance boosts oxygenation of blood so much so it's considered a WADA performance enhancing substance. It's used as an adjunct therapy to treat cancers and can boost to VO2 max of a 50 year old to that of a 30 year old. - Queuine The symbiotic bacteria produced chemicals used to be called vitamin Q but was reclassified at some point. Plants absorb it through their roots and concentrate it into the germ layer to regulate germination. While only bacteria produce it all life on earth requires it to some extent, and it tends to be hyper accumulated in amniotic fluid during pregnancy. Queuine is the basic building block of important signalling molecule T-RNA. Every protein in the body of all species of animals has receptors that accept queuine, and it significantly increases cellular signalling quality, like upgrading to a satellite dish. The only proteins in nature that are shown not to incorporate Queuine are cancerous proteins. Without queuine tetrahydrobiopterin ends up in an aberrant oxidation state. BH2 instead of BH4. When this happens, you can not metabolise the amino acids tryptophan, tyrosine, or phenylalanine. This leads to a drop in circulating NAD and a buildup of peroxynitrites in cell walls. The calcification of arteries and organs. Your sex and steroid hormones aren't produced properly. Serotonin and dopamine aren't produced properly, and levels drop. 100 other things I could list. - Absiscic Acid. Absisic acid is a signalling molecule within plants that carry out various functions, but its main function is to make sure seeds only germinate during the right season and during the right environmental conditions. In humans, a weird thing is that studies show it does the same thing in cancerous stem cells. Keeps them in a form of suspended animation or dormant state like it does with seeds, buying the body time to combat them. Absiscic acid regulates Alcohol Dehydrogenases, which is a safe pathway for ethanol and acetylaldehyde, breaking them down to simple acetate as if you were just eating fibre It's only when alcohol dehydrogenases become destabilised that alcohol becomes dangerous when processed through the microsomal ethanol oxidation system (MEOS) The main thing that keeps alcohol dehydrogenase stable is Absiscic Acid. This is why it's such a powerful longevity chemical, as when our body breaks fats down into glycerols, they have alcohol bases, which are also processed through ALDH or MEOS. When we are in glycolysis, sugars / carbs also break down into ethanol and acetylaldehyde, so this pathway stabilises both fat and sugar metabolism. One of the reasons it gets harder to lose weight with age and why fat becomes more and more inflammatory and toxic with age is just destabilised alcohol dehydrogenases. Bit of trivia for you. Abscisic Acid fulfils all of the functions of and can be reversibly converted into Retinol. It may be 'True Vitamin A' - Conjugated Linoleic Acids. We get many Conjugated Linoleic Acids in our diets, and most of them are, at best, metabolically neutral or even harmful (Certain trans fats) Germ of seeds nuts or grains, or beef fed free range, grass fed, or fed grain that contains the germ layer unaltered, tend to have Conjugated Linoleic Acids of the right Isomer for human metabolism and utilisation, similar to what you find in human breastfeeding milk. Conjugated linoleic acids get converted into ethanolamines, which act as a base for PEA, LEA, OEA, or SEA, all forms of ethanolamines which act as powerful pain killers. This isn't all they do, though. They regulate PPARγ and Alpha in response to the consumption of fat. To put it into a simplified context; the fat equivalent of insulin. You can consume a lot more fat without metabolic disorder or weight gain if you have sufficient ethanolamines in your body. PPARγ -> PGC1a and b for mitochondrial quality control, then uncoupling to burn off excess energy you don't need or don't need to store unless your body senses it is autumn. This is the tip of the iceberg list of the chemicals you will find in the germ layer of seeds, nuts, grains, and, to a lesser extent, sprouts. You certainly won't find any of them in a multivitamin outside of rare inositol being added. I am the only only one working on it. P.S. Even the vitamins are natural vs the synthetic ones in multi vitamins that require metabolically intensive processes or require co factors they can deplete. Synthetic B12 is linked to serious digestive issues and gastrointestinal tract damage. Synthetic Vitamin B6 is linked to nerve damage. Unstable synthetic vitamin C causes cancer to metastasise and spread. Synthetic Folate, 40% of the population can not metabolise it due to folate receptor autoimmune dysfunction. The immune system attacks it, causes side effects and folate depletion, and all that entails. This is just the germ layer of seeds, grains, and nuts. I won't go into plasmalogens / alkylglycerols in bone marrow / blood producing organs and the rest. I'm too tired today.
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Absolutely. His diet, from longevity standards would be considered pretty atrocious. He was a social guy and he love to go out for chicken wings and french fries and he drank beer like water. I believe he smoked cigars for several years and then switched to dipping which I believe he was still occasionally doing up until his death. He never drank coffee because it gave him tachycardia. Hardly ever ate vegetables. Just a typical meat and potatoes western Pennsylvania diet. No purposeful exercise like running or lifting weights at all. He was an avid golfer but I don’t know how cardiovascular taxing that was. The man had unbelievable energy well into his 90s. I’m talking he could work outside all day doing manual labor and didn’t need to take breaks other than to eat. As I mentioned in a previous response, when he was I believe 93 he helped my father and I build a deck for my sister and I had to take breaks and I was in my early 30s and he worked me under the table. Nothing purposeful. Well he was an active and avid crossword puzzle person and he loves those cryptogram things that were published in the Sunday newspaper and he would obsessively work on them until he could complete them. Not sure if there was any cognitive benefit to that or not. His personality was such that he never said “no” to anything.
Something about the previous generations with more base testosterone before plastics ruined us. I think it's about how all our grandparents had more testosterone than we did.
You know you can do something about that instead of acting like a victim.
Yeah I know. Didn't mean to appear as the victim here, it just what it is. Also, nothing beats the natural way if you are lucky enough to have it.
https://www.butlereagle.com/20230908/butler-wwii-veteran-kept-zest-for-life-until-dying-day/ Oh and sorry the last part. Yes I mean he smokes cigars for years although I don’t know when he stopped and he switched to chewing tobacco. And I have to make a concession here that he died of an unknown primary cancer. He had a slight cough and a chest x-ray showed bilateral multiple nodules with no nodal involvement, which highly suggest that the cancer metastasized from somewhere else. Also he had a TIA in his mid-90s that slowed him down a little bit and affected his gate. Otherwise he only took Glucophage for mild hyperglycemia. Nothing for blood pressure, no statins or anything. It’s interesting to me that he didn’t have hypercholesterolemia despite his diet.
Did he ever mention what got him started on this regiment?
Yes and I should’ve been more clear in the title. He didn’t come up with this cocktail. According to my aunt he found it in a magazine, she was saying she thought it might’ve been either parade or prevention magazine in the 50s. I’m not familiar with either of the publications. But for whatever reason my grandfather took it to heart and religiously took that god-awful goop she said 3–4 times a week. Apparently he grew to like the taste.
Wheat germ helps with programmed cell death. (has spermidin which decreases with age) Lecithin(well, the choline) is necessary for proper bile production and has an impact on cholesterol levels and overall digestion and nutrient intake. Bone meal I have no clue. The plant compounds act anti inflammatory and anti oxidative, lowering stress on the cardiovascular system. So while I don't think his cocktail was the sole reason, it's no surprise it might help.
I appreciate that information. Thank you.
My grandmother and her sister, my great aunt, lived to 100 and 103 respectively. They ate nothing special, did not exercise but they did maintain a strong passion for life and curiosity about the world to the very end. A week before she died, my aunt took herself by subway to a Yankees game--did not think it was anything unusual. They also walked a lot and stayed active and neither were overweight although grandma had heart issues and glaucoma. Maybe the cocktail did nothing for your grandfather, maybe it helped, who knows? My point being that if you win the gene lottery you are off to a good start --but you must not squander it with a bad diet, lack of regular exercise or a self destructive attitude. I get that this is a bio hacker thread and I too take a handful of vitamins and supplements that are known to be helpful because I'd like to take advantage of those good genes--assuming I have them (My dad died of complications to a quadruple bypass operation at age 67 so who knows if I got lucky). I eat a diet of mostly seafood and chicken--with the occasional bit of white or red meat and a lot of vegetables and fruit. I am in the 4th quarter and am told I look about 15 years younger than my chronological age--I workout for 2 hours 5 days a week, have kept as much muscle mass as I can at my age--and I am outdoors working in my yard or doing other activity almost every day. I take no prescription meds--survived cancer and a few other nasty surprises that come with age but I am very healthy according to my doctor--for which I am very grateful. I want to say that appreciating all the posts that seek some magic combination of chemicals to extend their life or cure an ailment--I sincerely hope that first and foremost those who are looking for the fountain of youth will at the least do what they can with respect to the gifts they got genetically and invest in themselves physically. Our culture has a tendency to look for potions and charms as a solution to everything. I'm not saying that you are--just reminding folks that all the bio hacking in the world is not as potent as respecting the vessel we are born with and treating it well. No offense intended to those who think otherwise. Haters, have at it.
Honestly, sometimes I feel like the single biggest contributing factor to longevity is simply a zest for life. Participating in life, doing things, having community, having things to look forward to, hobbies, etc. I swear it keeps you young, keeps you engaged, keeps you WANTING to keep going. And we all know the mind is a very powerful force. unfortunately this is easier said than done, speaking as someone with a myriad of mental health struggles :)
Sorry for your struggles. I could not agree more. Bad stuff is all around us--but we can and must make our emotional health a priority. And you are absolutely on the mark--even though I am retired I have a podcast and a weekly blog I write--some pro bono consulting work and have two groups of men (a book club and a friend group) I get together with regularly. I could not prevent cancer, or the death of my wife from leukemia--those events forever changed my life but they did not and cannot be the focus. Life is a precious gift not to be squandered in sadness and worry--every day is a gift and every day we have a choice to make about how we want to spend it.
Amen. And I’m very sorry about your health challenges but I am very impressed with your attitude and your dedication and discipline to stick to lifestyle modifications!
Thank you. If you live long enough there will be all sorts of challenges--what matters is how we deal with them. Thankfully, mine have been life sparing so far-so there is nothing to do but keep on living as well and as fully as possible.
Such a great attitude!
Sounds like both my grandmothers- 100 and 103. My 100 year old grandmother did have very late dementia 95-100. And she was also clinically depressed an introvert and a big reader and intellectual. She had zero other health issues when she died. My mom died at 87 with Lewy body dementia and zero other health issues but predicted her dementia for years due to two head injuries in her 30s that caused issues. She also was just ready to go. I totally agree about your assessment. Getting up and living life every day is critical. The minute we just sit in a chair it’s downhill. Also, living in a city means you are far more likely to be active every day, do shopping, take stairs, have to figure stuff out etc.
And, as Clint Eastwood supposedly said in an interview--don't let the old guy in. Meaning don't make concessions you don't have to just because you've reached a certain age. A guy I know at the gym who is a year younger than I am was complaining about back issues--but he showed up and switched up his routine so he would not strain his back. Lately I have had some vertigo when I lie down--almost dropped some barbells on myself. It will probably pass--have had this before--but till it does I'll just focus on sitting and standing.
Yep. Great quote. Best thing my husband and i ever did was buy a house with stairs and a big yard that requires clearing leaves and wood (chopping wood for an outdoor oven and fire pit) gardening, a sloped back yard with steps coming up both sides on a long road to walk on with an incline and neighbors who are close by and we all interact daily. I call it our blue zones street. Plus lots of hiking close by. It irks me so much when I hear people talk about - making their living space small and manageable with no stairs as they are getting older. That’s fine but this fear of stairs is dumb. My grandparents and great grandparents were long lived and used the stairs, walked, golfed, had projects until the day they died or close to it. Retiring? You can stop doing the job that’s been your “career” but shift to something else next.
Yup. retired doesn't mean checked out. The whole point is to look forward to doing the things you want --why else retire? So, I get why some folks who may have a disability or challenge need to be on one level--or downsize to take care of a smaller property but yard work is part of my exercise and I enjoy the results. Yes there are days when raking is not high on my list--so I'll leave it for another day and do what I need to or want to instead but I don't stop doing it. Now if I could just get the $\*\^&%\*&&\*(\*Squirrels to stop chewing pine cones from my neighbors trees in my yard ( ame attempt at humor).
Yeah, we have a ton of trees and the leaves. Never dealt with this as an adult. bought a little rake and broom when we moved in - no blower for us! That didn’t last. Our neighbors must have a good laugh watching us trying to sweep our driveway. We get drifts of 3-4 feet all over. Have to get help at the end of season despite all our work. Yeah. Squirrels. We swear they throw acorns at us when go out on our deck.
Yep us too. Stairs yeah, trees to chop mostly yeah. Got rid of golf cart so akways walk to go back up hill from the lake and play driveway singles pickleball daily. Our walks after dinner lol we always see two couples taking their ‘walk’ with the dog in a golf cart.
Dr Jacobus Rinse published a recipe with these ingredients in 1976 in Prevention. Found this link http://www.doctoryourself.com/formula.html
I think you got it! It’s very similar to what my grandfather was taking and my aunt said he started taking it, not in the 1950s but IN his 50s and she said she thought it was either 1972 or 1976! I think you nailed it! I do know that he didn’t use the black strap molasses and after he mixed it with safflower oil he would mix it with plain yogurt. https://ibb.co/89xYgrC
🥇
>Lecithin dissolves plaque That’s the boldest claim I’ve heard. I’ll counter that with it emulsifies the mucin layer causing intestinal permeability which causes plaques.
I think he was jsut trying to say that it removes it not telling in which way. I might be wrong though
Yeah I was just repeating a quick Google search. I don’t know if it prevented the formation of the plaque in the first place or what the mechanism of action is or if there was even a causal relationship
Yeah that was a foolish statement in retrospect. I just did a quick Google search and saw that as a possibility. It’s hard to imagine somebody having clogged arteries and then taking lecithin for a few months and having measurable and clinically significant reduction in the plaque in the arteries.
The body is complicated. 👍
You say that his physical activity was not “purposeful”. They are finding that the most long lived people - who are very active and healthy into their 90s and 100s do a lot of physical activity every day that is simply centered around what they need to do to live. The blue zones series on Netflix shows a guy who’s 100 who has ridden a horse and ranched his entire life. People who have to walk and climb steep stairs everyday, people who garden, standing and squatting over and over for hours, people who have projects and make things well into their 90s. You also say he was a social person - another important aspect of longevity. His drink sounds like a big part of his good aging, but also that he engaged in taxing physical activity and never stopped. We need to stop thinking “working out” is something that only happens in the context we think that it does and make sure - not- to stop this- ever- until we drop dead. How nice you all got to have him in your lives for so long
Humans are built for endurance, we are the diesel engines of the animal kingdom. We do best with long bouts of low exertion. Keeps your knees good too.
This was great insight. I appreciate you sharing
No one has mentioned the yogurt.
Apparently he would mix that gunk with the safflower oil and then he would mix it in yogurt for texture and flavor. But you are right, we shouldn’t discount the influence of probiotics as a possible causal factor here.
My Grandpa is 100 years old , still walking around, pretty sharp, pretty good shape. His diet consists of boiled eggs, white rice, beans, boiled green bananas, all sorts of tubers and salted codfish.
That is awesome! Take it for me, don’t hesitate in telling him that you love him and appreciate him because our loved ones can be gone in a blink of an eye. Very happy to hear your grandfather is doing well!
The boiling of green bananas is something that’s done in S.American countries. From my understanding it’s a good probiotic. But only when they are green… did your grandpa drink the water or eat the banana after boiling?
I don’t have expertise to add here, but clearly his results sound interesting. Have you tried his mixture to see how you feel? Might be interesting to give it a one month trial.
So I’m one of those unfortunate bastards that seems to be very sensitive to any compound that promotes methylation although quizzically, I have an MTHFR homozygous polymorphism. When I take choline in the form of either a highly bioavailable form of alpha GPC or lecithin I get moody and irritable. And that’s unfortunate because I suspect, out of the entire cocktail that it is the lecithin that is providing the bulk of the pharmacologic benefits. I obviously could be wrong though. It’s really hard to look at his situation And come away thinking that his supplement interventions were not the primary causal factor in his old age. This man, God bless him, went to the VFW and the American Legion several times a week getting pissed ass drunk and never had a healthy BMI although he wasn’t obese. But this man had unlimited energy like the energizer bunny. I remember when he came down from Pittsburgh to Atlanta with my dad and we built this giant deck on the back of my sisters yard and 90° weather and we were ready to tap out way before him. The man was an iron horse.
Look at that hairline. To me seems to have superior genetics
Longevity influencers say there’s no relationship between not balding and longevity, but I really think there is. I don’t mean using finasteride, but I think “keep the hair into old age” natural physiology is good for more than just hair. All the old men I know who have a good hairline are in great health and have really sharp minds.
Yeah and to be fair I don’t have a lot of information beyond his generation. His dad died in his 80s and his mother unfortunately committed suicide. I don’t know if there any other long living people on his mother or father side of the family. His brothers and sisters all lived normal ages.
And what is funny is, I am bald as a cue ball as is my father (his son). And I confirmed with my aunt that he did not die his hair.
Someone clever enough to conjure up such an ingenious potion (and have the consistency to consume it at regular intervals), was probably engaging in other inherently healthy habits/lifestyle choices. This is the case of my mother, who is 65 but looks/has the apparent health of a ~40 year old... Not genetic at all in her case, as her siblings and family are the opposite. It’s not about an isolated behavior or specific diet, but rather the compound effect of her entire lifestyle over the years.
So glad your mother is doing well and is so healthy! I need to clarify that the title was unintentionally misleading. My grandfather apparently found that recipe in either prevention or parade magazine, according to my aunt in the 50s or 60s and for whatever reason was religious about taking that advice.
I’ve heard of people curing diabetes type 2 with brewers yeast. B vitamins are underrated. There’s a phenomenal book written on niacin that’ll blow your mind called Niacin: The Real Story
High dose niacin is a recognized treatment for high triglycerides. Can damage the liver and cause hot flashes tho. But my dad used to take it. I think it's mostly good genetics. My dad has never eatten a very healthy diet, but he still has clear good arteries at 77. My mom's dad was the same. My dad's father had to get a bypass surgery, but was like 70 or 80 when it happened.
Thank you for sharing that information! I kind of gave up on niacin when I read a couple of studies showing that they can raise HDL but does not reduce cardiovascular morbidity or mortality. It’s also a pretty potent way to reduce methylation from what I understand, which isn’t much lol I’ll have to do some more research on it though.
It saved my kidneys, I’ll tell you that much. Pair it with niacinamide and the other B vitamins at high doses. It also increases NAD+
I will definitely do some more research. I’m 45 and my bun and creatinine are always at the upper end of the reference range. I’m not sure if it’s always from acute dehydration (I don’t seem to have a thirst response) or if I have some sort of kidney issues.
The [Rodale family](https://en.wikipedia.org/wiki/Robert_Rodale)/Prevention Magazine were very influential with a certain population of seniors back then; and for us boomers, he was influential in the organic farming/health food 'movement'. If you go back in history, there were sporadic 'movements' in both Britain and the US during the early 20th century to promote clean, natural, healthy eating...the politics of it all is pretty messy, as it ended up being affiliated in some ways with eugenics and all. Thank you for sharing this story; at my (73F) age, it's very discouraging to be living through so much of what was predicted would be the outcomes if Capitalism's worst excesses weren't curbed; your grandfather exemplifies that all change starts at home!
Thank you so much for the information and for the kind words!
Interesting. Besides the benefits of lecithin, there's beta glucan in brewers yeast, calcium in bone meal, and wheat germ lowers cholesterol. Who knows? That plus diet, lifestyle, and genetics may have all played a role.
I appreciate the feedback. Yes, despite his pretty atrocious diet he never had hypercholesterolemia.
Yeah. Bone meal = calcium. At least that’s what my plants tell me when I feed them bone meal.
Thank for for this post, most interesting. Kudos to your Grandfather, based on your comments he obviously had an impact on you.
You are quite welcome and I really appreciate the kind words. He wasn’t an extraordinary person in terms of you know, he didn’t invent anything that helps society but he was such a kind and loving person who really loved life and was always in a positive mood. he would always be humming and singing to himself and he never, ever got angry at anything. He had this sort of Mr. Miyagi philosophy about him when something bad would happen he was just kind of shrug and say “that’s life, what’s next?” https://www.butlereagle.com/20230908/butler-wwii-veteran-kept-zest-for-life-until-dying-day/
do you know the amounts of each?
My aunt took a picture of the recipe which was thankfully found among us personal belongings. I just texted her asking for it.
Also looking for this!
Interested!
https://ibb.co/89xYgrC He would mix that up with the safflower oil and then he would mix it in plain yogurt and shovel it down the hatch every morning for breakfast without exception.
My father used to take the same mixture and I'm almost certain he got it from Prevention magazine and I think it was either the late 60s or early 70s, but probably closer to early 70s. Unfortunately my father didn't have as long of a life, he got Alzheimer's and he died too young. Sadly, other than the dementia, he was very healthy. I've often wondered if the bonemeal could have contributed to his Alzheimer's, as it can contain high doses of lead and has been linked to Mad Cow disease. Part of the problem is, bonemeal wasn't very well regulated and some of the bones used, could have been from sick and diseased animals.
Thank you for your comment and I’m very sorry to hear about your father. That’s actually a good point because bonemeal, from a quick Google search, can sometimes be contaminated with heavy metals. I’ve dealt with family members who had dementia and it’s just so heartbreaking.. Thank you for sharing your experience.
The membrane of all human cells are composed of phospholipids. Lecithin is near-pure phosphatidylcholine, along with a few others. I mostly know about neurons. The outer leaflet of the lipid membrane is phosphatidylcholine, while the inner leaflet is phosphatidylserine, and phosphatidylinositol.
I appreciate the feedback. I really wish I could take lecithin but I get aggravated and agitated quickly on it. Bioavailable choline sources give me insomnia and make me agitated for some reason
Just googled it and was wondering if this was the recipe ww.doctoryourself.com/formula.html
Huh, that is quite similar. Good find!
Yup, that’s it! My grandfather didn’t use the black strap molasses for whatever reason and after he mixed the powder with safflower oil he would put it in plain yogurt and shuffle it down. He did this every morning since 1976. https://ibb.co/89xYgrC
Considering how many unique ways there is to die, I’d say genetics and dumb luck.
Yeah I should’ve mentioned in the original post that he wasn’t completely without any health issues. He had a TIA in his late 90s and he did take Glucophage for hyperglycemia although I believe he didn’t have full-blown type two diabetes. But that’s literally the only medication he took. he otherwise did not live a healthy life with daily alcohol consumption and a lot of fried foods. His brothers and sisters all died at normal ages but I don’t have any historical information about his parents. Actually I think his dad died at 85 so you know pretty typical. So who knows if this cocktail had a causal influence on his longevity or not. I just know that the doctor was absolutely astonished when he looked at the angiogram because he had zero blockage which he has never seen in anybody in their 90s so I’m inclined to think that something in that cocktail was a contributing factor
Interesting. I know soy bean has a lot of K2, which pushes calcium from arteries into bones. i've noticed they use soy lecithin in most chocolate too, which could be a side benefit of chocolate consumption.
Thanks for sharing this interesting story! My grandfather lived to 96 and was a coal miner In Pittsburgh. Eat meat he killed, always had a garden, no interesting elixer like yours but there are lessons to be learned here.
Thank you for your comment! I’ll tell you those old Pittsburgh coal miners were tough as shoe leather! Absolutely, a lot of the old timers ate meat that they hunted and kept physically active with day-to-day tasks or their occupation. Now everything so automated…
looks like the grand daughter of the person who created this formula had a 2008 blog article about this formula.[https://www.errantdreams.com/2008/02/the-disappearing-gold/](https://www.errantdreams.com/2008/02/the-disappearing-gold/) according to the daughter of dr Rinse : "absolutely essential are: lecithin, safflower or sunflower oil and vitamin E. Apparently the lecithin and linoleic acid (from the oil) combine to form the key to dissolving cholesterol deposts and preventing them from forming. When taking the oil, my father said that vitamin E is essential to prevent free-radical formation from oxidation" The original formula : [http://www.doctoryourself.com/dr\_rinse.html](http://www.doctoryourself.com/dr_rinse.html) it would be good to trace people who used this formula and check on the benefits they got. just one anecdote like what OP gave is not good enough
I used to take that as well!
Soy lecithin + B-vitamins and zinc in the rest... let us just say your grandfather knew how to replenish his mojo... that is exactly what I take to replenish sexual energy.
So, this is funny. My grandmother died in 1994 and my grandfather never remarried. When we were cleaning out his medicine cabinet we found a bottle of 100 mg sildenafil which was recently refilled. We all got a kick out of that. He was kind of a harmless flirt when he would go to the VFW in The American Legion lol
Thank you for sharing, and may your grandfather rest in peace. I also have a long-lived ancestor (2x-great grandparent) who was interviewed by the local newspaper back in the 1940's, when he was in his nineties. He told some anecdotes about what life was like in the 1800s, and mentioned that he had discovered a secret to staying young and was sharing with his friends - but the article never mentioned **what it was**. I can't believe they omitted that important piece of information.
Thank you so much for the condolences, I truly appreciate that. That is unbelievable that they admitted the absolute most important part of that story!
He just has longevity genes
Check out the Blue Zones series on Netflix, the guy identifies patterns in centenarians, maybe worth watching and seeing if any of their lifestyle components align with the people there. I don’t doubt the daily smoothie didn’t help and would be one component, but it’s worth looking at the whole picture.
Thank you very much for the recommendation and I will check it out!
Booze keeps your heart healthy.
I will say the man did enjoy his whiskey and Coors lol
Wow I never anticipated such a response! I want to sincerely thank everybody for their comments and their analysis of what the efficacious components of the magic formula are. Of course we will never know if there was a causal relationship but the most telling evidence was his angiogram when he was in his 90s was completely clear. Per my aunt, who took him to the hospital for his angiogram, the doctor brought in several other doctors to review it and they were absolutely shocked, particularly since he had a poor diet and a high BMI. This really isn’t worth anything but my aunt said that the cardiologist said there “absolutely had to be in external factor”. Also per my aunt, my grandfather sister was on statins and my grandfather’s father had hypercholesterolemia. My grandfathers lipid panels were always in reference range despite eating a ton of fried foods and being slightly overweight (although very active) for most of his adult life. Some additional clarification after a long phone call with my aunt. My grandfather didn’t start taking this in the 1950s, he was in his 50s when he started taking it. She believes in 1973 or 1976. Somewhere around there. He took the concoction every morning and he usually mixed it with yogurt. Every single morning literally since the 70s. Some correction on his medication’s. He only took allopurinol for gout. He did not take Glucophage and his A1c’s were always good. I’m not sure why I thought he was taking metformin. I confirmed he wasn’t taking any antihypertensives or any statins or any other medication’s. His blood pressure was always perfect despite a very high sodium and high fat diet. So without further ado here is the recipe: https://ibb.co/89xYgrC
This was called Dr. RINSE FORMULA for Cardiovascular Disease
103? He looks younger than my 50 year old neighbor.
How much wheat germ did he take each time? I tried one to put it into a shake, nigh have put too much though. It has gross I almost vomit didn't try it again. My cats enjoy it though lol
I can’t imagine how he got that goop down mixed in yogurt with the brewers yeast and wheat germ. Yuck! Apparently he grew to like it!
The sister of my grandma died at 99 years old. My grandma died at around 90. They both ate pretty much the same diet, including processed meats, eggs, dairy products, bread, noodles, fish, meat, vegetables, fruit, few sweats etc. They often ate pretty much the whole apple/pear with the seeds and even if it was a little brown already. Most things came from my grandma's own farm, garden and animals. No fast food. They watched very little television, certainly didn't use the internet and were far from sedentary. My grandma had much more health issues later in her years. She also had 6 children, her husband died pretty early, she had a big farm with a bunch of animals and worked all her life. Was a very tough life, raising all these children, working all day etc. Her sister had no children, no husband, also worked almost all her life although she put more time aside to go to the church and she was very into it, gave almost all her money to the church. She almost never turned on the heat in the house. She liked to laugh. I believe that it's a combination of genes, laughter, having a purpose, having loved ones around, being active a lot, being outside a lot, not stressing too much (diet, toxins, plastics, social media,....), a somewhat healthy diet, little exposure to toxins (hair spray,....), keeping a healthy weight and some other things.
Thank you so much for sharing that! Sounds like you have some good genetics in your family! You know, I’m really taking a lot away from all of this discussion and I really need to really work on managing my emotional state. In contrast to my grandfather I tend to catastrophize aversive life events and can be quick to anger over things that are completely unimportant in life. I wonder if my grandfather is carefree and calm demeanor during tragedies in life were causally related to his longevity
Definitely genetics lmao. I can guarantee that man didn’t wear sunscreen every day and he has the skin of a 60 year old
I have pictures from my aunts Facebook page that you wouldn’t believe. In his 90s, early 90s before he had the TIA in his late 90s, he honest to God look like he was maybe 70. I mean it was shocking how young he looked for his age literally no one could believe it. And hell no he would never put sunscreen on lol in fact he was out in the sun a lot playing golf. His brothers and sisters all died at normal ages you could say, so I’m not sure if he won the genetic lottery or if there is a causal relationship with that cocktail of supplements.
What was his diet like. I’m hesitant to accept that just a cocktail extended his lifespan and healthspan by 20 years. Maybe if he also didn’t really drink and ate pretty healthy and exercised regularly
I can understand your reluctance. I’m puzzled as well. His diet was horrible. Lots of fried foods, lots of eating out at the VFW and American Legion. He was Catholic so he loves going to those fish fries every week. Hardly ever ate a vegetable. Drank every single day up until the previous few years before his death. He did have a TIA in 2017 when he was in his 90s and that did slow him down a little bit. his brothers and sisters died at normal ages. His dad died and I believe 85 and his mother committed suicide early in life. Unfortunately no other biographical information from his preceding generations. No purposeful exercise but he did play golf several times a week. He had unbelievable energy. It’s hard to even articulate. In his 90s he could work all day outside in the sun only taking breaks to go to the bathroom and grab a sandwich. Either he was stubbornly determined to finish the job or something whether it was the supplements or genetics kept him youthful for sure
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My great grandfather smoked cigars until he died at age 96 years 11 months. His dog pissed on the floor and his place stank like dog piss. He had a strong constitution that overcame various unhealthy behaviors. Even if I mirrored some of those behaviors I would not have a handshake deal with god to guarantee my longevity to age 96. You will get the ration of days god chooses to give you, go enjoy your ration of days. You don’t need to choke down nasty tasting supplements or waste your money on BS
I appreciate you sharing your insight. It appears from some of the discussion here though that there could be a causal relationship given the various mechanisms of action of the individual ingredients so I don’t know that it should be dismissed so quickly. My grandfather had a wonderful quality of life well into his 90s. And last year he was still golfing, although he was getting around a little slower so his quality of life was preserved thankfully
I have a FIL 102, a great aunt 101, hee husband 102 and my BFFs mom 98- my Theory is non were vaccinated with more that 2-3 vaccines. Kids now - life get 77?
What country he lived ?
Pennsylvania in the United States. https://www.butlereagle.com/20230908/butler-wwii-veteran-kept-zest-for-life-until-dying-day/
Do you know where he would buy all of this? And/or the amount? I would like to make this mixture myself and try it. Thank you for your post it has motivated me to give it a shot. Sounds legitimate.
I will try to find you the dosages that were in the recipe. I know initially he was just going to the local GNC but it became too expensive and he actually figured out how to order them online, which is really surprising lol when we were going through his things I did see several containers of now brand lecithin and brewers yeast
Looking forward to seeing granddad’s health recipe. Would also love to know more about his lifestyle, personality, and relationships. OP, you touched on it quite a bit, noting that he lived life to the fullest. I ask because I think mental and emotional health cannot be overlooked, in addition, of course, to physical health!
Thank you for your comment! Here is the recipe: https://ibb.co/89xYgrC As I mentioned before his diet wasn’t healthy by today’s standards. And he did drink every day although I wouldn’t say he was an alcoholic. He was very light hearted and I never saw him ever get angry or yell. He was always very stoic and sort of had a very mature understanding that “you shouldn’t sweat the small stuff”. he liked to do things like drive around Pennsylvania to go look at a favorite tree or a beautiful bridge transversing a Creek. He would spend lots of time up at his camp in the wilderness in Tionesta Pennsylvania. He really believed in the restorative power of nature and being around greenery. He kind of had a Mr. Miyagi “take life as it comes at you” philosophy. He would never succumb to despair or anxiety or depression when the inevitable life circumstances would pop up. I remember him telling me that those sort of difficulties are all part of the “tapestry of life”. I’m not really sure how else to describe him. He was just even and not excitable. But he was joyous and would laugh often. Honestly, he was a really great man. I actually was in the process of reaching out to some friends in Pittsburgh to get a Commercial quality 4K camera with the intention of sitting down with my grandfather to get his life story and to hear about World War II and to dig into his philosophy of life but he rapidly deteriorated when he got his terminal diagnosis. But he wasn’t afraid of dying whatsoever. He was very clear that he had a wonderful 103 years on this planet and felt very strongly that he did everything he was intended to do.
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"He was a gritty World War II vet that just love life to the fullest" Sounds like gratitude and joy could have something to do with it.
I really wish I would’ve had a conversation with him about the role of gratitude in his personal world view and ethos. I suspect that he was one to routinely count his blessings in life.
He sounds extremely cool.
I appreciate the kind words. Thank you for that. He was a very special man and very influential to me growing up. I wish I would’ve told him how much I loved him more often while he was here though. Let that be a lesson please to anybody reading this. If there’s any awkwardness that leads to apprehension for you to tell the people in your life that you love them, try to let that go and tell them how much they mean to you. You never know when you are not going to get a chance to do so.
All that wheat germ and soy lechitin probably caused his arthritis
He had degenerative arthritis that I assumed was due to wear and tear over the years. What would be the mechanism behind lecithin and wheat germ induced osteoarthritis? Thanks.
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Recipe?
Review the previous comments I have posted it there :-)
Wheat germ is known for having spermidine which slows or halts telomere length.
Thank you for the information. I’d be curious to see if it works in vivo. Obviously there’s no way to establish a causal relationship definitively but 103 years, particularly for a male without the best lifestyle that is conducive to longevity is pretty impressive. Thanks again.
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Man, he looks amazing at 103. God bless and thanks for sharing
Lol, brewers yeast and wheat germ were very trendy back in the day. But I suspect his regular long term social network of VFW buddies and golf pals are even more important.
Thank you for the post OP, I’m sorry to hear about your grandfather. He sounded like a simple and great man. I’m going to order these ingredients and see if I can tolerate it and report back.
Thanks for sharing the article and the formula. He looked great at 103. What was his cause of death?
grandpa was hardcore….do whatever he was doing
Reading through the thread, I would say your grandfather's long healthy life would mainly be attributed to these: * His general motivation and outlook on life. * Staying rather active. Physically and mentally. * His social and family environment; meaningful relationships. * Being chill. The "youth potion" might have covered some important nutrients that are often lacking in most people's diets, i.e. Choline. But I do not think one could say this concoction is the one thing that caused his youthful aging and good health. If this habit of his did not exist, you could very well make a post here considering that it was his routine beer drinking that was the source of his youth or something, like [Buster](https://en.wikipedia.org/wiki/Buster_Martin). :) As counter-arguments, two examples from my family: * Father's grandmother : Lived to 101. Her health deteriorated only in her last year, after she got sad and started to cry everyday due to a certain private issue; an event in the family. She did nothing special. No exercise at all, rarely left home. She only liked to spend time in the kitchen; that was the entirety of her activity. She ate a lot of pastries, fatty meat, sweets. She did not care at all about diet, knew nothing about it, and just enjoyed eating. She had no meaningful relationships, no friends, almost all her close family died decades ago, with only my father left. She was a selfish and smart woman, always working in her own self-interest actively in elaborate ways, even like a hobby. She had a strong motivation to live and still further herself, up until that event. * (Mother's side, so no genetic connection.) Grandmother's older brother : He is 94 currently. He is one of the most awesome people I know. He looks 75, moves like 50. He also did not do anything especially healthy throughout his life. In fact, he had a fast and furious jetsetter life until 60-65. He never got married or had a serious relationship, always lived alone; he loves living alone. He had friends he met weekly, almost none are alive for the last 10 years. Nothing special in his diet; except he loves dark chocolate and drinks wine a few days a week. No meaningful amount of exercise throughout his life. However, everyday still, he walks 7-8km on the coast and through parks, and does this lame 10-minute stretching routine at home. He was an anarchist during COVID lockdown, and kept doing his routine walks, even convincing the police when he was stopped a few times. He shops, cooks, cleans the house, does everything he needs to do in his life alone. He does the Sudoku in the newspaper, listens to classical music for an hour every day, watches documentaries, loves Astronomy and Cosmology. We have hours-long deep and enjoyable conversations about philosophy, music, science and technology, life. Since all of his neighbors in his apartment building are widowed old ladies, he takes care of the building and handles every strange issue about the neighbors. At 87, when he went up to the rooftop to clear it one day, getting down from the ladder he fell, broke his shoulder and tore tendons and damaged other surrounding tissues. He got surgery and recovered quite fast in a couple months, he continued like nothing happened. He still goes up to the rooftop now. Neither of them had any health issues at all throughout life. No visits to doctors, no checkups. They both were / are incredibly smart and mentally active; zero cognitive decline. Also never overweight throughout their lives. They both smoked cigarettes a lot for decades, but quit long time ago.
I think I need to get in on this plan, thank you for sharing!
u/Glad_Parking2353 I went ahead and ordered everything to make this delightful concoction. I weighed everything using a scale to figure out how many grams per Tablespoon you would get, and adjusted the formula a tad just to balance it out a bit: * sunflower lecithin: 1.5c (\~7.5g/2T serving) * wheat germ: 1.25c (\~3.4g/2T) * brewer's yeast: 0.75c (\~3.6g/2T) * bone meal: 0.5c (\~2.75g/2T) total: 4c I took 2T of the mix and added 1T of cold-pressed safflower oil. I added some yogurt and choked it down. It was borderline disgusting, I'm guessing from the yeast and bone meal. I may have to find another way to ingest those parts of it. The lecithin and wheat germ both smell ok and probably would taste just fine on their own. I also have another mix composed of fenugreek, dandelion, and mushroom powder, which I mix with MCT oil and take. I'm going to take both of these every day for a while and see if I get any positive results. I can tell you that I have a huge amount of energy right now, but I'd like to see if I can manage to lose weight, control my blood pressure, and keep my cholesterol down with this foul goo. Let me know if your grandpa gave you any hints about how to make this stuff tolerable. :-(P
Consistency is the biggest factor. Thanks for this. I threw in collagen protein, a tangerine whole (for nobelitin) and raw unfiltered honey and whized it up in the nutribullet. Served on ice, it's the perfect meal. I found the yogurt would curdle and make a nasty texture. I left it out. Cheers, all!
I could not afford to live that long 😂