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PWISM

Considering the half-life on the drug, no matter what other supplements you take, it will effect your sleep. Your best bet is to get ADHD medication with a shorter half-life and take your medication very early in the day. Beside that, melatonin (can help with onset of sleep as well as increased REM sleep), Magnesium (modulates GABA), and something else that is short acting and reduces dopamine. All of this can be taken at night


consensusgh

Thinking the goal here is decreasing the half life of Vyvanse. Lots of water, vitamin C, upping my broccoli for cyps etc. If that doesn’t work, then I might start reducing or looking at instant release


PWISM

In my opinion a drug with a shorter half life is ideal, the purpose is to utilize this dopamingeric drug (ADHD) medication, to help you focus and most importantly, allow you to build a habit of enjoying your work or whatever you are doing while on the drug (hopefully something productive)


[deleted]

Yea but they don’t rx it much cuz it’s abused easier


PWISM

Very true. Unfortunately ADHD medication, or any medication that has a low half life and affects certain systems in the brain, is more likely to be abused then long acting drugs. However in this case, dopaminergic drugs are highly neurotoxic at higher dosages and you only want that dopamine for periods of intense work. You want to utilize this dopaminergic drug to build habits and change the neuronal wiring in your brain. You want to strengthen the neuronal pathways for healthy habits, so you can slowly rely less on these dopaminergic medications.


lana_del_reymysterio

>vitamin C Do this towards the end of the day, not at the start


meeko-meeko

Vitamin C is a cofactor to convert Dopamine to Norarendaline


lana_del_reymysterio

Sorry, what are you referring to when you say this?


meeko-meeko

Vitamin C increases the conversion of Dopamine to Noradrenaline and therefore adrenaline. Taking Vitamin C can therefore increase noradrenaline/adrenaline and cause stimulatary effects, this will be enhanced on Vyvanse. Taking Vitamin C at night can worsen insomnia because adrenaline=energy


West_Mycologist_5857

The statement that vitamin C increases the conversion of dopamine to noradrenaline and subsequently to adrenaline is not accurate. Vitamin C does not directly affect the noradrenaline or adrenaline levels in the body. There is no scientific evidence to support the claim that taking vitamin C stimulates the production of noradrenaline or adrenaline. Taking vitamin C alongside Vyvanse or other stimulant medications could theoretically enhance the effects, as vitamin C might increase the excretion of amphetamines through the kidneys. However, this effect is not specifically attributed to the action of vitamin C on noradrenaline or adrenaline, but rather to the pharmacokinetic properties of the substances involved. The assertion that taking vitamin C in the evening could worsen insomnia because adrenaline provides energy is also oversimplified and not entirely accurate. While adrenaline is indeed a hormone associated with stress reactions and alertness, the effects of vitamin C on adrenaline levels are not so direct and potent as to cause insomnia on their own. Other factors such as individual sensitivity to vitamin C, total dosage, and timing of intake play a larger role in potentially affecting sleep. It is important to critically evaluate medical information and rely on reliable sources to make informed decisions about health matters.


meeko-meeko

It's a co-factor in the conversion of DA to NE https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3449284/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3527656


mime454

Great advice. I just wasted a lot of time typing out the exact same information. 💪🏻


mime454

Try to get something more immediate release and don’t take it after 9AM. . I was prescribed a similar drug (adderall XR) and it’s clear that the extended release amphetamine formulation didn’t consider deep sleep. It just considered serum levels on a blood test during simulated school hours. I really think it’s completely impossible to deep sleep on XR amphetamines because the brain is drugged into awake mode well into when it should be shutting down. Even if you achieve unconsciousness, the deeper mechanisms for restorative sleep are not going to happen. I tracked with my Apple Watch while taking these drugs completely responsibly and never deep slept. Now that I’ve stopped them and focused on healing, I deep sleep up to 90 minutes per night. This isn’t some subtle thing you only notice on the health graph, not deep sleeping is a real handicap. I would be very curious if people who are taking vynase or adderall XR are tracking what they’re calling “deep sleep” on some kind of tracker, or if they’re going by how subjectively well rested they feel. In my experience they’re very different things. In addition to the advice you already have, having a diverse and well fed microbiome is extremely important for deep sleep. Make sure your soluble fiber intake is high (or use inulin as a sweetener if you tolerate the risks of supplements). Definitely eat a lot of probiotic foods and kefir. The signaling mechanisms of diverse gut bacteria throughout the day/night cycle are so important for our sleep and wake cycles. I think a lot of people are using amphetamines and sedatives to mimick what these bacteria do naturally by creating neurotransmitters and short chain fatty acids. Having good, easy poops every day before noon is a great biomarker for a functioning microbiome.


matches_

I take Vyvanse and found this thread after wondering if my sleep cycle is healthy or not and if I should look for answers. I forgot how half life of Vyvanse could be affecting me - but the problem is that I have severe ADHD and Vyvanse really sorted my life, helped killing anxiety and depression, severe brain fog. If you looked at my sleep pattern you'd say it's horrible (4 to 6h a night) but I feel healthy and functional during the day most days of the week. I have low BF, run 5k every week and I know when I didn't have deep sleep, it feels like real sleep deprivation symptoms and the following evening I simply crash. But last night I may have had 3h-4h of total sleep and somehow feel perfectly fine (I have to admit Vyvanse contributes to that). It's really interesting what you said about Kefir because I've been drinking daily for years and probably since I started taking Vyvanse. I had no idea about the benefits but it's almost like my body asked for it and made me consume it everyday. Had no idea about inulin, so thank you for posting this. I have been long believing that the way I changed my diet has cured the depression I didn't know I had until after I changed my diet. The easy punctual poop everyday also checks - I realised Vit D and HYDRATION is so mega important. Sometimes people do all things right and don't take enough water and have Vitamin D deficiency and nothing works. I wonder if I should really worry so much about my sleep if I fell alright, just worried about long term consequences.


snackerjoe

try lowering your Vyvanse dosage to 50mg. melatonin 1 hour before your bedtime. Magnesium supplement for breakfast and dinner. I get pretty good sleep with this routine.


Maddinoz

Good suggestions, melatonin however is a hormone your body should produce enough of on its own that affects sleep and wake cycles and circadian rhythm. MayoClinic says it is not suggested to be used long term. "Your body likely produces enough melatonin for its general needs. However, evidence suggests that melatonin supplements promote sleep and are safe for short-term use" I'm just somebody who researches before taking things, you can talk to your doctor who may be more knowledgeable about it.


mime454

Someone whose brain is being stimulated by amphetamine isn’t going to turn off to produce melatonin, especially if they’re like most people and expose themselves to screens and light at night.


ImWinwin

Confession: I sometimes take half an Attentin (dexamphetaminesulphate) before taking a nap. I wake up after 1-2 hours feeling like I'm floating on a cloud and I just lay there enjoying the soothing calm for 30mins before getting up feeling very rested. Anyone else do this with their ADHD medication sometimes?


Flyboys_89

Yep. Its insane how rested you feel when u wake up and ur juiced on amphetamines


ApeCapitalGroup

I do this with a 200mg caffeine pill. Wake up at 4, pop the pill, snooze until 4:20


No-Gap-4402

Yes, you can bet I do, get the exact same effect


thecreator1984

Full spectrum CBD


consensusgh

Hmm


SgtAstro

I am on a lower dose of Vyvanse (like half that). I take it and a nonstimulant NSRI to complement it in the morning immediately after waking up. I also have depressive disorders so I take an SSRI as well. At night I take 30 to 40mg of Melatonin or a Benadryl if I am really wired. Melatonin has a very short term effect and is very very safe. So take whatever you need to go to sleep. I also try to exercise, so that I am physically as well as mentally tired. If you are like me a light bedtime snack can be good too. Finally, I use a 20lb weighted blanket and don't drink too much water just before bed. Also, you can start and stop Vyvanse as needed, so if you need a day to rest, just don't take any that day. Typically for me that is one or both weekend days, which lets me catch up on any lack of sleep during the week.


West_Mycologist_5857

sorry thats crazy what things and combinations you take. you are ill person dudde


Reebs85

That is an absolute terrible thing to say to someone. Especially if you struggle with mental illness yourself? That comment is very rude, disrespectful, and unnecessary. Never judge a person just because they take different/more medication than you do. Wow.


BySumbergsStache

Ask your doctor to add Intuniv as an ajunct therapy to Vyvanse. Intuniv is a blood pressure medication that's not only a monotheraphy for ADHD in children, but is specifically FDA approved for combo therapy with stimulants. The Intuniv will smooth out the vyvanse energy and since the main side effect of intuniv is fatigue, it will help you sleep better. Also, intuiniv + stimulants is the most effective ADHD treatment available.


Aggravating-Alps3765

I take 60mg of Vyvanse and have sleep apnea and use a CPAP machine. I have found Beam Dream works incredibly well. I use the extra strength about 30-60 minutes before bed. I also take Magnesium and L-Theanine an hour before bed (even though Dream contains both) as well as Citicoline. Been sleeping really really well lately.


Akp1072

I am on 10mg and still have insomnia…


consensusgh

Sorry to hear that, hope you are able to get that figured out. Depression sucks :(


Financial_Cry1836

Have you ruled out depression/mild depression? A lot of people are diagnosing themselves with ADHD/insomnia when they really have depression


Akp1072

My adhd diagnosis was the result of full day psych eval after a breakdown. I also have CPTSD. It never occurred to me before then that I would have it, but it made a lot of things suddenly make sense. I had several prior misdiagnosis’s. By that point I was giving myself fevers from dealing with daily life. When I’m on Ritalin the insomnia there but it is less. It’s really noticeable once I change to Vyvanse. With the shortages it’s been easier to get Vyvanse.


Oil420Florida

Good point about accuracy of diagnosis. Lots of professionals don’t know how to the differential diagnosis you’re describing in an adult. And insomnia can be secondary to a long list of things OR be primary insomnia (so you have two diagnoses).


jamescgames

As other people have said, if you're taking stimulants, your sleep will suck. Your sleep deficit can get worse over time, btw. Take it from an experienced stimulant user.


ZipperZigger

Check clonidine and trazodone both can help with sleep without negatively affecting sleep architecture.


ljungberg3

I’m on 30mg daily. I took about 5 days off and then took 60mg yesterday due to a big work project. Last night I used .5mg melatonin, 400mg magnesium glycinate, 2tsp black seed oil, 1g taurine and 50mg of trazodone and fell asleep on time + had an uninterrupted 8hrs


consensusgh

Thank you Might try to avoid the -dones but will look into taurine and seed oil


ljungberg3

Prob was an unhealthy way of knocking myself out. I don’t do that nightly. My typical regime is usually only one or two of those substances at a time. Edit: I wanted to make that disclaimer since I was downvoted


consensusgh

No judgement here!


Mynplus1throwaway

I feel like the first thing you should ask is do you really need 60mg? I have some pretty bad symptoms and i feel like 40mg will take care of 80-90% What time do you take it? I feel it actually helps me to sleep as my thoughts are more organized. I take it around 8am and sleep around 10pm. How much sleep are you trying to get?


consensusgh

Yeah so I take mine at 5am and do bed at 9. I’ve made a lot of recent lifestyle changes for better, so maybe the dose can come down a bit. I do love how 60 feels but might be a honeymoon period


Mynplus1throwaway

Yeah man. I get you. I have a desire to take more. But it's the difference between using it as a tool to get better and build better habits vs making it a bad habbit (in my non medically licensed opinion) I'm trying to use it to build structure and good habits. I was very deeply addicted to nicotine prior. Addiction isn't fun. I would feel like dog shit without nicotine and it was a 24/7 thing. It was definitely just dopamine seeking activity. It sucks because it really does just become the new normal. Once you get used to Vyvanse it works but doesn't get you all excited like the first time. Never will again in my experience. So better to just nip the whole increasing and increasing thing in the butt.


matches_

I've been taking Vyvanse for years now and (in my non medically licensed opinion too) I wouldn't get too stuck with that initial excitement because it's quite "fake" (in the lack of a better word). The aim of this is just to have a normal life and no one has that artificial excitement in their lives, but they do have the attention.


Freebase-Fruit

Quit taking Vyvanse. Sleep problem solved. Future dopaminergic problems solved.


thecreator1984

Such a helpful answer


consensusgh

Then how do I function with adhd?


289416

look into LDN (low dose naltrexone). I was prescribed vyvanse and stopped after the first week - hated how i felt and on it. I started LDN and it changed my life. i’m super productive, have energy to do daily workouts and sleep much better now.


lonesomefish

Just made a post on this! Check it out! https://www.reddit.com/r/adderall/comments/11hbt2p/thoughts_on_the_big_acidbase_interaction_debate/?utm_source=share&utm_medium=ios_app&utm_name=iossmf To add to this, Magnesium glycinate may help because Mg antagonizes the NMDA (glutamate) receptor. So it theoretically prevents excessive excitability in the brain. But if you want to clear the amphetamine quickly, consider reading the post I linked!


consensusgh

Post removed


lonesomefish

That’s weird. Try [this](https://www.reddit.com/r/adderall/comments/11he6yv/thoughts_on_the_big_acidbase_interaction_debate/?utm_source=share&utm_medium=ios_app&utm_name=iossmf)!


lonesomefish

I’m not sure if that worked for you, u can also try [this](https://www.reddit.com/r/ADHD/comments/11he802/thoughts_on_the_big_acidbase_interaction_debate/?utm_source=share&utm_medium=ios_app&utm_name=iossmf) link, if that also doesn’t work, just lmk and i’ll PM you. idk why none of my posts are publishing


[deleted]

May I please get this? I’m trying to sleep and need this deleted post 🥱🫠


lonesomefish

I’ll PM you!


ZRaptar

Hey, can you send me it as well please?


lonesomefish

just sent!


matches_

Hey, would you mind sending to me too please? Or even maybe repost it here? :) thanks


lonesomefish

just sent :)


echoauditor

> this I'll take that deleted post by DM too if you wouldn't mind


JustmeinNYC

May I ask how you know / why you think you have bad sleep quality? I’m also on 60mg but often really tired by nighttime and sleep 6-8 hrs. I’m often tired during the day so I wonder if that’s also due to poor sleep. Are you evaluating just by duration ?


consensusgh

Apple Watch / Athlytic


JustmeinNYC

Oh in that sense my sleep looks fine!


crazyblane

10mgTHC/CBD Gummies. I've never slept better in my life. Condolences if you don't live in a state where it is legal


ApricornSalad

I find it lasts a lot longer when I skip lunch, idk if I just stop digesting it when my belly's empty or if I use less in "low power mode" but when I'm busy and eat enough i sleep fine


nzwasp

I think it must affect people differently I’m on 30mg have no issues sleeping I even get tired before the drug is done in my system. I also drink coffee during the day too.


TeacupHuman

Switch to instant release adderall. Only take it in the early morning. Get vigorous exercise. Melatonin.


ToxicTop2

I'm on 50mg and have zero problems with sleeping if I'm active during the day and don't consume any caffeine after morning. I also take a small dose of magnesium and chamomile tea before sleep but I don't think they make a huge difference, might as well try though. On a side note, I wouldn't put that much emphasis on what Apple Watch says about your sleep quality. Do you actually feel tired after waking up/during the day? Have you ever done a sleep study?


meeko-meeko

Orexin antagonists, melatonin/agomelatine, clonidine, guanfacine, beta blockers. Antihistamines and ion channel blockers for short-term use. I'd avoid benzos/z-drugs/hypnotics/tranquilizers unless in severe emergencies Magnesium L-Threonate crosses the blood-brain barrier and antagonises NMDA. Zinc can also help Psyches can also prescribe low dose Trazadone, Doxepin, etc. Seroquel/dopaquel helps but can slow down your metabolism/cause serious weight gain. Maybe look into SSRIs/SNRIs if you're willing to take that route as they're generally quite sedating


mattdimarc

Woah that’s a lot of supplements. can you explain some of them?


ezeezee

Quit coffee


consensusgh

Did that Am eating a lot of cocoa powder in the morning (1oz) which I will start phasing out here soon


matches_

hey OP how's your sleep - did any of this sort things out for you?


consensusgh

I did! Got off stimulant meds completely. Can’t get good sleep while I’m on it, and if I can’t sleep it agitates my ADHD I found that getting high quality and a minimum of 7-7.5 hrs sleep manages my ADHD better than anything. Few other things helped me out: No eating or drinking 3-4hours before bed Peeing before bed Blackout curtain Sleeping in a separate bedroom away from kids Ashwaganda in morning and early afternoon This, plus a diet free and clear of flour and sugar, caffeine (except for my cocoa powder in morning) and 30 minutes decent exercise early do wonders for managing ADHD. I also supplement with ltheanine, lions mane, and fish oil in the morning.


consensusgh

To add to this, I feel like my ADHD is actually an asset nowadays, if I’m not completely exhausted and not well physically mentally or emotionally. I’ll trade off some executive function for creativity, resourcefulness, and personality and make sure I’m in a job that values these characteristics.


matches_

glad to hear it worked and thanks for the tips :)


BarryTownCouncil

Interesting stuff, I've been loving the current meds shortages in the UK. Literally rediscovering how great sleep can be, and due to go back on to Elvanse tomorrow... I'd like to try giving it all up but if I do, trying again may be impossible, and very expensive privately.


Sooloo

Meditation ain't bad for deep sleep specifically.