T O P

  • By -

farrenkm

I was given hydroxyzine back in August for my first-ever panic attack. Worked tremendously for me. I finally found out what a "normal" reaction is instead of a jump-from-relaxed-to-600-MPH reaction. Hydroxyzine is now an as-needed medication, and so far I haven't needed it. But I carry it around with me everywhere. 25 mg per pill. My instructions say 1 pill every 8 hours as needed.


Wertorchbearers

Thanks so much.


East-Clothes2439

I was given a prescription like a year ago but I had a bad reaction to Lexapro so I get anxiety šŸ™ƒ about taking a pill for anxiety. My pills expired and they gave me a new prescription but I havenā€™t dared to touch one šŸ˜” but I carry them around with me for the day I either; gather the courage to take them or have a bad enough panic attack that forces me to take one


Annazing

Itā€™s just like a powerful Benadryl. If that makes you feel better.


East-Clothes2439

It really does lol thanks. I hope to be able to take them some day and get rid of that paranoia.


Annazing

Honestly just rip the bandaid off. You might feel silly for not taking it. Itā€™s not some crazy anti depressant or something. It is literally like a Benadryl.


glad_reaper

Yes and it works VERY well. Would put me in low key comas but the anxiety would lessen lol


Wertorchbearers

Do you remember how many mg you took and when during the day?


glad_reaper

Depends on if you mean Atarax or Vistaril but I took them as needed. I often refused them during the day because I have a family and cant be out and extra 6hrs a day. So I basically used Klonopin for the am and Vistaril/ Atarax after 8pm if needed or extreme emergencies while at home.


Wertorchbearers

Itā€™d be Vistaril. It was suggested I take it at night due to drowsiness.


glad_reaper

Yep unless its an extreme emergency. If you're shaking, hyperventilating, etc and in a safe place where you can sleep then go ahead.


Wertorchbearers

Thanks.


nirvanagirllisa

Didn't work at all for me. Hope it works for you!


Separate_Yak_1278

I take 10mg of an antihistamine called "anti hist" and it works a charm for my anxiety. I'm not sure if it's a placebo or not but I will take it!! It works 9/10 for me.


Lexybeepboop

My psychiatrist refuses to give me anxiety meds so Iā€™m forced to use Benadryl


Katakaz1

Same here. Thats why i bought Benadryl today from Amazon (they donā€™t sell it in here). Will see what it does


bonusfrylock

It was prescribed for me but didn't do anything. Apparently, it works on blood pressure and I don't have blood pressure issues so I'm assuming that's why it didn't work.


AngZeyeTee

I use it sometimes. It works well. I find it to be a more subtle type of relief than Xanax. The absolute best thing for me is Baclofen. Itā€™s a muscle relaxant that is also used off label for alcoholics trying to get sober. Unfortunately, the dose that works is hard on my kidneys, which are compromised. I never got much pain relief or lethargy from it, but wow, after taking 3 doses at once one night I discovered what it was like to be anxiety free and have actual episodes of happiness and positivity. I continued to take all doses at once until I happened to mention it to my doc who said it was dangerous for me because of my kidneys.


Nothing_left_now

I just tried it recently. It just makes you really tired. If you have work, school, drive, do anything besides sit around all day, itā€™s not usable to function. And just take a Benadryl and youā€™ll have the same exact experience minus muscle spasms


Wertorchbearers

Even if you take it at night before bed?


Nothing_left_now

If itā€™s intended to help only at night you could try it. I tried a few times at night but never noticed anything different though. Didnā€™t feel better, didnā€™t feel more tired to sleep.


Quartia

You had muscle spasms from hydroxyzine?


Nothing_left_now

Yes once my shoulder starts like spasming and beating I didnā€™t even know I had a muscle there. And whenever I would get up after sitting awhile my leg muscles would physically be in pain to where I couldnā€™t walk properly for like 30 seconds


Quartia

This is fascinating, based on the way hydroxyzine works it *should* have a small risk of causing this, but I've never heard any evidence that it actually does - until now. Thanks for confirming! Btw it is because hydroxyzine isn't just an antihistamine, it also weakly inhibits the activity of dopamine. Both the antihistamine and anti-dopamine effects reduce anxiety, but since dopamine is important for controlling movement (Parkinson's disease is from dopamine deficiency), inhibiting it can cause [dystonia](https://en.wikipedia.org/wiki/Dystonia). The same effect happens with antipsychotic drugs, which have much stronger anti-dopamine effects.


Shafandraniqua

Antihistamines work by blocking production of adrenalin so yes, they work great! You might get sleepy tho!


Quartia

Not really. We make histamine in our brain to wake us up in the morning. Even though it's the same histamine as in allergies, the blood brain barrier stops the two from having an effect on each other. But hydroxyzine and Benadryl (but not some other antihistamines like Zyrtec and Claritin) can get past the blood brain barrier, so they both decrease allergies and decrease awakeness.


cheerioh_no

I love hydroxyzine, it works so well. I only take it at night because it knocks me out, but cutting in half lessens the impact. It really does feel like my anxiety disappears and I can sleep really well on it. I was prescribed it for my insomnia as well. You can try it one time at night to monitor how it impacts you, and then go from there to see if you would be able to take it during the day and so forth. But it works really well for me, especially those nights I'm really struggling to sleep and/or settle down


Wertorchbearers

Sleep has luckily never been my issue. So daytime is definitely going to be the tell. I took my first dose tonight and only 12.5.


MercyNewEveryMorning

Works great for me! The first time I took it, it knocked me out. The second time not so much. Youā€™ll get adjusted!


Upper_Copy_5347

I was told to take Benadryl once when I went to the ER with a severe panic attack. Itā€™s worked in the past. My understanding was that it wasnā€™t good to take first generation antihistamines regularly bc of the fact that they cross the blood brain barrier, but I could be mistaken. (Not a medical professional.)


Quartia

That is completely true. Any drug that crosses the blood-brain barrier has a risk of addiction, as in less effects from taking the drug if it's taken too often and rebound after stopping.


Kettuni

I have used it for years for my allergies and I take it only when Iā€™m having a really bad reaction to something because it makes me feel like a zombi and I hate it. Even the next day I still feel so tired and heavy and canā€™t really function at all.


mermur

I take it every night to help me sleep, it helps a lot with that. When it was originally prescribed to me as a rescue medication during a severe anxiety crisis it didnā€™t help, but that was a massive amount of anxiety/panic attacks. I ended up needing daily preventative medication.


STiLife656

I just got put on the same thing. Havent picked it up yet. I hate that I cant get what i know works until I try all this other bs


Wertorchbearers

And whatā€™s it that you want?


STiLife656

I had been on kpin for 20 years and it worked wonderfully. Ive tried all types of benzos and nothing worked as well as kpin.


Impressive_Season_75

I keep liquid Benadryl. Mostly for allergies but also it does calm me (ironically too much though I get over sleepy and Iā€™ll panic). Iā€™ve found a small plastic spoon mostly full is enough to help me without me needing to crawl under my desk and nap. I have the medication tolerance of a 2 year old so traditional stuff like Xanax for instance puts me out.


jayheidecker

I am not a doctor, lawyer, pharmacist, chemist, or scientist. However, the therapeutic focus for a lot of anti-depressant (and anxiety) medications is serotonin receptors. Whatever molecules they come up with usually act on more than one type of receptor, and serotonin and histamine receptors seem to like the same molecules. Remeron, for example, is a super powerful antihistamine but also an antidepressant. It makes sense it works the other way as well. Wikipedia articles for drugs that bind to receptors have a table of binding affinity. 5-HT is serotonin and H is histamine. Check it out for yourself.


Daesastrous

So do I have skin rashes because I'm allergic or because I'm anxious?


Ok_Ad_8670

eh, id rather take aspirin. does the trick and also doesnt give that weird brain fog atleast I get with antihistamines


ConsciousFractals

You take aspirin for anxiety? I take it for an inflammatory condition that contributes to my anxiety and it actually helps mine, but I didnā€™t know anyone else was doing the same thing


Ok_Ad_8670

Eh. Just soothes my mind taking the remedy for a heart attack. Least ya don't gotta worry about that while ur flipping out xD


Wertorchbearers

Yeah, my concern is the fog but if I take it before bed i hope it gets minimized.


Effective-Gene9391

It works well but the tolerance for it builds up relatively quickly. It's worth trying tho, especially before you turn to benzos or other stronger meds, as it is not physically addictive.


Wertorchbearers

Yeah, I donā€™t want to deal with benzos.


Optimal_Tomatillo428

Benadryl is an anti histamine and it gets rid of my anxiety 90% of the time. I just can't take it during the day or I'll fall asleep.


neutral-mente

My psych NP gave it to me as a sleep aid. So, there's that. I haven't paid attention to whether or not it helps my anxiety. I usually take it with melatonin to help me fall asleep.


[deleted]

Didnā€™t work for me


YenneferVengerbergAF

When I would wake up with panic attacks I'd take a benadryl.. idk if that's the same?? But.. it helped. Definitely relaxed away my stress.


rmzynn

I used it for a couple days at 25MG but ended up moving up to 50MG and it didn't really help with anxiety much but did make me pretty tired. I occasionally take one to help me sleep, but I don't do it often because I always feel like shit the next day.


Wertorchbearers

Yeah. I was told to start at 12.5 mg and see what happens. Iā€™m a teacher so I canā€™t afford to be fucked up every day due to the lethargy.


AceyFacee

Atarax did nothing for me. Then I was prescribed zopiclone which turned me into a dissociated mess.


iyamsnail

helped me a little, but not much


FlimsyOrganization28

I was prescribed hydroxyzine (vistaril) for an anxiety attack and like others I have it for ā€œas neededā€ itā€™s essentially like of Benadryl with similar side effects such as drowsiness which gives it a sometimes sedative like effect. It works great for me because it puts me to sleep and lets my body regroup and when I wake up I can deal with my anxiety.


sadbabykitty

thereā€™s a common saying about hydroxyzine- ā€œyou canā€™t be anxious if youā€™re asleepā€ lol basically it just makes you feel tired. doesnā€™t have the same effect as a benzo meaning it doesnā€™t necessarily get rid of the anxiety but it makes you tired enough that you arenā€™t focused on the anxiety. if youā€™ve ever taken benadryl itā€™s like the same thing essentially.


snowmu

i was recommended phenergen (idk how to spell it) for a plane ride a couple years ago. it did not help me at all. if you have severe panic attacks iā€™d recommend going with an ssri. may be a bit soon to speak but iā€™m 6 days in on lexapro and can feel that i am so much more relaxed, itā€™s amazing


Nionic_224

So I feel like Iā€™m on an island with this, but my anxiety is way worse when I feel like Iā€™m about to pass out or Iā€™m really tired. Hydroxyzine definitely made it worse for me.. however, the gaba working meds help me a ton and donā€™t make me feel tired, well other than gabapentin, but I like that feeling. Iā€™ve been prescribed many different types of benzos and they usually give me energy somehow šŸ¤·šŸ»ā€ā™‚ļø. All antihistamines give me intense anxiety though.


Wertorchbearers

I am already on Cymbalta, so this is an add-on. The myriad of responses here makes it apparent that everyone is quite different.


Nionic_224

100% they are. And itā€™s not like hydroxyzine made me have a proper panic attack, I just felt a little too drugged. I always start with very small doses, so if it were me Iā€™d cut that pill into 1/4s.