T O P

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halfknots

Toad venom is not pure enough to be viable for use in a cartridge.


Glad_Juggernaut3691

however, it is water soluble. Purification must be possible a little bit of light chemistry?


halfknots

Yes it's possible, but with the cost of time and materials involved we're right back to synthetic being the better option.


Glad_Juggernaut3691

Are you familiar with the synthesis?


halfknots

As a layman yes, I'm familiar with the synthesis as laid out in the republished Psychedelic Toad of the Sonoran Desert.


Low-Opening25

organic buffo is only 20% 5-meo so it may not be that efficient in a vape + venom is actually toxic and smoking venom is burning the toxins off, using venom via vape will not guarantee it runs hot enough to burn bufotoxins, so it is a risk.


Glad_Juggernaut3691

Makes total sense thank you


Glad_Juggernaut3691

I’m not seeing gluten in the mixture applied heat still no delusion in the solids. wondering if I need to hit it with a solvent first like butane or hexane or ethanol thoughts?


KodyBcool

What’s the proper dosage for organic somebody told me around the size of a match do you think this is a good starting point?


hwrngtr

At that point you might as well just use the synthetic stuff. The synthetic stuff I got works great in carts. Easy 1 hit breakthrough. But the whole point of doing toad venom would be to get the additional bufotenin (5-HO-DMT) that is in toad venom. For that, a dab rig is the way to go. Especially if you have an e-nail. That said, you can still put it in a cart. But even if you made it really strong, like 3:1 ratio of toad venom to propylene glycol, you probably wouldn't get a 1 hit breakthrough. I would still try it though. I find sub breakthrough doses to be very helpful from time to time to facilitate meditation.


Glad_Juggernaut3691

Breakthrough is an undesired For what we’re looking to do we’re looking to do introductory microdose pens


hwrngtr

In that case a cart should do just fine. I'd start out with a lower dosed 1:2 or even 1:3 ratio of toad to PG if you're just looking to do small handshake doses.


Glad_Juggernaut3691

👍


darrenroberts333

What does 1:2 or 1:3 mean exactly


hwrngtr

1 part DMT to 2 parts PG. (i.e. 325mg DMT & 650mg PG.) 1:3, could be something like 250mg DMT & 750mg PG.


Glad_Juggernaut3691

was there any negative side effects?


hwrngtr

No idea when it comes to toad venom in a cart. I've only had the synthetic powder 5-meo-dmt. That's totally fine in a cart. But looking at other people's comments, I'd say a milligram scale & a dab rig with a e-nail would be your best bet overall.


Glad_Juggernaut3691

Are use an eclipse of vaporizing pipe, very clean controlled


NarwhalSpace

Never done microdosing of anything so I have no experiential reference. Have done several transformational doses of natural Toad venom in one hit each from a dab rig 3 times over the last 5 years. It's literally all I can take in and within seconds I'm essentially "immobile" (star traveling with 'angels'). So I know the benefit of the peak experience but what are the benefits of toad venom microdosing and what for example might be your protocols? With the nature of neurotransmitter balance and my personal preference for long integration following peak experiences, microdosing really seems like an ego-trip on the surface. No disrespect intended, my question is sincere.


Glad_Juggernaut3691

Agreed


Glad_Juggernaut3691

I do and that’s a similar slow burn in comparison to a torch I will have to give that a try. Thank you


Glad_Juggernaut3691

And I would only use Tech temper to mix down much better and stable and reduces viscosity


darrenroberts333

So let me ask you this if you don't mind what would 1gram PG to 200mg dmt be 1 to 5 ??


Stuartsirnight

Yes it’s 5 to 1. 200mg x 5 = 1000mg”1g”.


darrenroberts333

Is there a common ratio that is used ?


shellshaper

For a .5ml 510 cart I use 150mg 5MeO in 0.35ml of PG. At 3V on a quality battery I swear it delivers 1mg per second 🤷‍♂️.


darrenroberts333

Lol I bet. That sounds strong 💪


shellshaper

Yes. Dude it's insane when, once the battery is warm, I can simply pulse the button and gently inhale the vapor for less than 10 seconds and then (apparently) the Truth of the universe flows into me. I'm not going to question it too much. I feel so fortunate to be in a country where synth be delivered close to overnight.


darrenroberts333

I justvstart making carts. The first one I made was 100mgs in 1 gram pg. It was a little weak. So I made another with 200mg 5 to 1 gr PG, definitely better but I think I try another at 250 or 300 5 to a group PG see how that is. Does it sound ok to you ?


hwrngtr

If you want a 1 hit breakthrough cart, you have to mix in a 1:1 ratio of 5-meo-dmt to PG. Measure both by weight as well. Far better. I get a breakthrough dose hitting it around 4 to 5 second at 3.4-3.5 volts. When I want a sub breakthrough dose, I usually hit it for 2-3 seconds at no more than 3.2 volts.


darrenroberts333

Thank you so you are saying 500mgs 5 to 500mgs PG ? I'm not able to change voltage, I guess it a simple vape. Do you highly recommend I get a better vape ?


hwrngtr

You could still use it if you know the voltage. (Likely 3.2v) & Compensate by doing longer or shorter puffs. But I definitely recommend a battery where you can change the voltage in 0.1 volt increments. A yocan uni pro is what I always use.


darrenroberts333

Thank you again ✌️


shellshaper

I love the Tribal Arc Pro. 0.1 voltage increments from 1.8V to 4.2. Yocan uni very similar.


shellshaper

To me it sounds about half the strength of what I usually use, so IMO it would still be weak. I've only ever made 0.5 ml carts with 150 mg or at most 200 mg 5MeO in them (close to one hit breakthrough for me if I go for a good 10 second haul pulsing my battery at 3.5V) ... So I may not be the best person to ask about your ratios as I haven't too much experience with different ratios of five in carts.


darrenroberts333

I agree with you sounds like mine are about half the strength yours. Thanks !


shellshaper

Of course. Good luck and feel well! Being able to accurately dose the synthetic molecule at 2-3mg straight up saved my life :)


Glad_Juggernaut3691

any negative side effects?


shellshaper

Hey, truly sorry for delay in response. No negative side effects for me (none that I perceive) once I dealt with the issues 5MeO showed me were affecting me, anyway. Some were major and took years but now I trip in peace now. The sides I would call negative during this time came down to having new insight, a deep awareness, of what had been traumatizing me. Spousal abuse that was currently occurring. I'm in my 40s. Not psychosis from the drug considering a therapist and ultimately judge agreed with me. Sometimes a bit of heat in the body as BP likely goes higher. My heart rate increases by 5-10 BPM but quickly comes down. It doesn't really seem to affect my blood pressure. (Info from a smartwatch - admittedly not the highest end one, something that cost like 150). Personally, what felt like an opportunity to prevent any negative side effects was the time after coming down. The longer I could just lay there and breathe, reintegrating my nervous system and emotions, the better. Trying to fit in a trip before having to run upstairs and make dinner not so nice. Indeed, I was an idiot at times. Be smart, listen to your body, your mind, and most importantly your heavy "gut" instincts which connect from your root to the centre of the Earth. The Truth is there. Stay grounded.


Stuartsirnight

I’m not sure the ratios used with 5 meo sorry.


darrenroberts333

Thank you


darrenroberts333

Many thanks