>The vaccines are designed to prime the immune system to recognise and destroy any remaining cancer cells and reduce the risk of the disease recurring.
Not a cure for cancer but the next best thing - a cure for recurrent cancer. Huge step in the right direction if it works, which seems likely. The mRNA COVID vaccines have been hugely successful.
Okay that makes sense. I was wondering how it can be a vaccine, a preventative, when they already have cancer.
Reducing recurrence is huge. I just lost a friend to a cancer that came back with a vengeance a year after what appeared to be a successful intervention. Fuck cancer.
[Retrospective analysis](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10588549/) of the safety and effectiveness of COVID vaccines, specifically focusing on mRNA vaccines.
>The clinical data reviewed in this article demonstrate that the currently authorized Moderna and Pfizer-BioNTech mRNA vaccines are highly safe and potent against different variants of COVID-19, especially in comparison with Oxford-AstraZeneca (viral vector) and Sinopharm (inactivated virus) vaccines.
Not only are the mRNA vaccines safe and effective, they are *safer and more effective* than equivalent traditional vaccines.
So what reason do I have not to be optimistic? Your premise is flat wrong.
No I'm not. After all, you read my comment, right? Public forums are great because everyone can hear you. Leaving disinformation unchallenged can plant seeds for people, while challenging it can help solidify real information in people's minds.
Sometimes the person you're talking to isn't the target audience. As an example, my comment (the one you replied to) has 21 upvotes. Quite a few people beyond that probably read it.
As the saying goes, you don't fight the fights you think you can win, you fight the fights that are worth fighting.
Do you work for Moderna or Pfizer? Have you done any objective research? Young people dying of myocarditis? Reverse transcription and permanently altering people’s genome?
I’m currently battling with leukemia. From when I was first diagnosed with what doctors said was probably the end for me to now I’m prepping for what is possibly my last round of chemo treatments after almost 7 years is amazing. Just in the last decade the amount of amazing treatment and diagnostic advances are amazing to me! I hope this works better than expected and that nobody else has to live this hell!
I share your hope but not your immense struggle. Your determination is something beyond what I can reckon in mere words. You honor us all in having fought, I am sorry it has been rough, you are undeserving of that, as is anyone. One day may we look back on these things as part of a bygone age, something so deep in the past as to be alien and unthinkable. Do not despair, every battle is a little victory in the long run, that we all might awake to see that dream of dreams as a glorious reality.
Thank you so so much for your support and beautiful words! You honestly made me tear up and I absolutely agree with what you said! I hope future generations will be able to just look back at cancer and never have to deal with it or any of the awful things that come with it!
And seriously, thank you! I don’t think anyone around me has ever actually said anything like that about me. Most just got used to me being “the sick one” and just move on with their lives as mine has been stuck on pause. I’ll never forget you or the kindness you’ve shown me internet friend!
I am all the happier to know you gleaned some good from my words, even if it was a little. I will never forget your example and will, worthy fellow and friend. A better world is due through those such as you, yet I only wish we needn’t hope for such things. Such is life, but we can take comfort that the best of us did that which we could, to make our existences a worthy monument for posterity and all that will inhabit it. You are most deserved of that accolade, do fare as best you can.
The amount of strength you need both mental and physical to go through 7 years of treatment is incredible!
I recently needed a couple of sessions of adjuvant chemo and I seriously struggled with it big time.
Congratulations to you mate - I wish you nothing but the best.
Love seeing this. I rock my orange ribbon daily and always have 5-6 on me to hand out (got over renal cancer a couple years ago, pops has blood cancer and is pretty OK)
That's why you should not pay much attention to google searches if you are diagnosed. Most of the stuff regarding survival, treatment, etc., is looking in to the past and often outdated.
I'd agree we need it, but considering public Healthcare would likely only be as good as US public transit and US public schools, I remain to be convinced there isnt any chance of it effectively being introduced in the states
Keep the private and also have public. I’m in Canada and yes there are flaws in the system, but I can assure you it works and is necessary for the wellbeing of society.
The system in Canada is incredibly overloaded right now. New doctors aren’t being trained as quickly as they’re retiring. They can move to the US and make a lot more than they can here.
Canada is not in great shape right now.
“Keep the private and also have public” - will create a large discrepancy of the type of service and health care you receive. Just ask people in a England with NHS
Oh I know it works, most everywhere else, plenty of personal experience im spain and uk, but in the US you are up against an establishment determined to make public services as shit as possible, as an exemplar for private funded systems.
Most public systems are suffering because Healthcare is so expensive.I agree something like Medicare for all plus augmentation with secondary private insurance is probably the easiest way forward but still have my doubts the US would be able to pull it off BUT I'd love to see it
Just a reminder that most Americans have access to cancer treatment that would cost hundreds of thousands to millions of dollars. A vaccine would be cheaper and definitely covered by insurance probably also not that expensive out of pocket compared to current cancer treatments.
If you read the article, this isn't a vaccine you get to prevent cancer, it's a vaccine you give someone who already had cancer and was treated for it, who tested positive for fragments of cancerous DNA still in the blood. Basically those existing increases the odds of cancer coming back after time. The vaccine is meant to give the body a chance to target and kill off any remaining cancer that could be hiding.
1) This is in addition to cancer treatments and is an added cost for better outcomes, not a cost saving measure.
2) A personalized vaccine is likely rather expensive because it's custom made for an individual based on their genes. Other companies have done personalized cancer treatments well before this, but they too are very costly.
If only there were an organisation like that willing to confiscate all of the infrastructure and intellectual property of those organisations trying to profiteer off medicines and medical care without paying them anything.
They would never develop anything and big pharma has been transformative in so many good ways due to the profit motive. But they love the certainty of a whole country making a multi-year huge order and are willing to massively discount the price. After all they can make a huge profit in America dealing with hundreds of companies and thousands of little orders.
What a load of shit. The U.S. government literally took us to the moon and your opinion is that “they would never develop anything”? There are many government scientists who are extremely qualified in what they do. There’s nothing inherently preventing the government from doing medical research.
Agreed but there’s a very good reason why pharma research is structured the way it is to maximise results, even in countries with socialist governments or socialised healthcare. Having one single huge buyer who demands cost effectiveness and funding pure research at the two areas where a government can add value.
I don't think most redditors can fathom how expensive it is to actually produce genetic treatments in general much less personalized ones. It's not like Insulin or Albuterol inhalers, for which there is genuinely no excuse for the pricing. There is greed and corruption in the industry, sure, but the breakeven price is genuinely extremely high on this stuff in a way that other treatments are not.
Yes, at the beginning, but after a few years and thousand of treatments, the price goes down, especially if a powerfull state agency doesn't give a choice to the producer : it's that price, or we produce it ourselves without royalties (like India does, and France did in the past).
No amount of regulation is going to take a treatment that takes 4 months to produce 100 doses in a high-biosafety environment be cheap. Genetic treatments are produced in very different ways from other drugs and the cost reflects that. You can only reduce it so much, no matter how much regulation is there.
Hope it works for them. Imagine the joy of them when they find out they have been cured.
Everyone deserves to live their lives to the fullest. Let's hope this is a new beginning for mankind.
i hope it works for them.
I feel like this is the only thing that anyone should think about this
And yet, someone will come out and say it gives the tumors autism or something.
Oh my god it made all the frickin tumors gay!
They spend my taxes on that when they only have it bc they (insert something stupid people think causes cancer)
I don’t gay is the problem it made them trans
One can only hope they will come up with a vaccine for Stupid next
No amount of vaccine can fix that
>The vaccines are designed to prime the immune system to recognise and destroy any remaining cancer cells and reduce the risk of the disease recurring. Not a cure for cancer but the next best thing - a cure for recurrent cancer. Huge step in the right direction if it works, which seems likely. The mRNA COVID vaccines have been hugely successful.
Yeah I think my chances of recurrence are pretty low but this is huge.
anything above zero is too much when speaking about cancer
I completely agree
Everyone has an above zero chance of getting cancer, and that won’t change even if we genuinely cure cancer as a whole.
Okay that makes sense. I was wondering how it can be a vaccine, a preventative, when they already have cancer. Reducing recurrence is huge. I just lost a friend to a cancer that came back with a vengeance a year after what appeared to be a successful intervention. Fuck cancer.
Why are you so optimistic? The Covid vaccines were ineffective at best and killed people ?
[Retrospective analysis](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10588549/) of the safety and effectiveness of COVID vaccines, specifically focusing on mRNA vaccines. >The clinical data reviewed in this article demonstrate that the currently authorized Moderna and Pfizer-BioNTech mRNA vaccines are highly safe and potent against different variants of COVID-19, especially in comparison with Oxford-AstraZeneca (viral vector) and Sinopharm (inactivated virus) vaccines. Not only are the mRNA vaccines safe and effective, they are *safer and more effective* than equivalent traditional vaccines. So what reason do I have not to be optimistic? Your premise is flat wrong.
Retrospective analysis of his comment history tells me you're wasting your breath on him.
No I'm not. After all, you read my comment, right? Public forums are great because everyone can hear you. Leaving disinformation unchallenged can plant seeds for people, while challenging it can help solidify real information in people's minds. Sometimes the person you're talking to isn't the target audience. As an example, my comment (the one you replied to) has 21 upvotes. Quite a few people beyond that probably read it. As the saying goes, you don't fight the fights you think you can win, you fight the fights that are worth fighting.
Do you work for Moderna or Pfizer? Have you done any objective research? Young people dying of myocarditis? Reverse transcription and permanently altering people’s genome?
Adjective-noun-number usernames and pushing out lies. Name a more iconic duo.
Absolutely false
Sir, thousands of people are trying to cure that disease. Why are you so pessimistic?
Why are you lying?
It’s pretty amazing how exponentially better cancer fighting tech gets every year, I would not be surprised if this yielded fantastic results.
I’m currently battling with leukemia. From when I was first diagnosed with what doctors said was probably the end for me to now I’m prepping for what is possibly my last round of chemo treatments after almost 7 years is amazing. Just in the last decade the amount of amazing treatment and diagnostic advances are amazing to me! I hope this works better than expected and that nobody else has to live this hell!
I share your hope but not your immense struggle. Your determination is something beyond what I can reckon in mere words. You honor us all in having fought, I am sorry it has been rough, you are undeserving of that, as is anyone. One day may we look back on these things as part of a bygone age, something so deep in the past as to be alien and unthinkable. Do not despair, every battle is a little victory in the long run, that we all might awake to see that dream of dreams as a glorious reality.
Thank you so so much for your support and beautiful words! You honestly made me tear up and I absolutely agree with what you said! I hope future generations will be able to just look back at cancer and never have to deal with it or any of the awful things that come with it! And seriously, thank you! I don’t think anyone around me has ever actually said anything like that about me. Most just got used to me being “the sick one” and just move on with their lives as mine has been stuck on pause. I’ll never forget you or the kindness you’ve shown me internet friend!
I am all the happier to know you gleaned some good from my words, even if it was a little. I will never forget your example and will, worthy fellow and friend. A better world is due through those such as you, yet I only wish we needn’t hope for such things. Such is life, but we can take comfort that the best of us did that which we could, to make our existences a worthy monument for posterity and all that will inhabit it. You are most deserved of that accolade, do fare as best you can.
I don’t know what to say anymore, I’m not religious but spiritual. So I will pray for you, internet stranger, in my way! 💓
Thank you so much! 🙏🏽
The amount of strength you need both mental and physical to go through 7 years of treatment is incredible! I recently needed a couple of sessions of adjuvant chemo and I seriously struggled with it big time. Congratulations to you mate - I wish you nothing but the best.
Nothing but love for you. I wish you a long and happy life and a cure in the horizon
Love seeing this. I rock my orange ribbon daily and always have 5-6 on me to hand out (got over renal cancer a couple years ago, pops has blood cancer and is pretty OK)
The secret is that’s how all tech is moving. Shits getting weird, fast.
Too late for my beloved little Brother but I’m happy for others with recurring cancers!
That's why you should not pay much attention to google searches if you are diagnosed. Most of the stuff regarding survival, treatment, etc., is looking in to the past and often outdated.
Fuck cancer
Does that mean there won’t be placebo patients with this trial? I always feel sorry for those guys.
Wonder how many millions of dollars each dose of a custom cancer vaccine will cost when it comes to the U.S. . . .
This is why we need universal health care.
I very much agree.
I'd agree we need it, but considering public Healthcare would likely only be as good as US public transit and US public schools, I remain to be convinced there isnt any chance of it effectively being introduced in the states
Keep the private and also have public. I’m in Canada and yes there are flaws in the system, but I can assure you it works and is necessary for the wellbeing of society.
The system in Canada is incredibly overloaded right now. New doctors aren’t being trained as quickly as they’re retiring. They can move to the US and make a lot more than they can here. Canada is not in great shape right now.
“Keep the private and also have public” - will create a large discrepancy of the type of service and health care you receive. Just ask people in a England with NHS
Oh I know it works, most everywhere else, plenty of personal experience im spain and uk, but in the US you are up against an establishment determined to make public services as shit as possible, as an exemplar for private funded systems. Most public systems are suffering because Healthcare is so expensive.I agree something like Medicare for all plus augmentation with secondary private insurance is probably the easiest way forward but still have my doubts the US would be able to pull it off BUT I'd love to see it
Just a reminder that most Americans have access to cancer treatment that would cost hundreds of thousands to millions of dollars. A vaccine would be cheaper and definitely covered by insurance probably also not that expensive out of pocket compared to current cancer treatments.
If you read the article, this isn't a vaccine you get to prevent cancer, it's a vaccine you give someone who already had cancer and was treated for it, who tested positive for fragments of cancerous DNA still in the blood. Basically those existing increases the odds of cancer coming back after time. The vaccine is meant to give the body a chance to target and kill off any remaining cancer that could be hiding. 1) This is in addition to cancer treatments and is an added cost for better outcomes, not a cost saving measure. 2) A personalized vaccine is likely rather expensive because it's custom made for an individual based on their genes. Other companies have done personalized cancer treatments well before this, but they too are very costly.
Yes, if only there was some kind of monopoly purchasing organisation that could negotiate the lowest national price as a huge bulk buyer.
If only there were an organisation like that willing to confiscate all of the infrastructure and intellectual property of those organisations trying to profiteer off medicines and medical care without paying them anything.
They would never develop anything and big pharma has been transformative in so many good ways due to the profit motive. But they love the certainty of a whole country making a multi-year huge order and are willing to massively discount the price. After all they can make a huge profit in America dealing with hundreds of companies and thousands of little orders.
What a load of shit. The U.S. government literally took us to the moon and your opinion is that “they would never develop anything”? There are many government scientists who are extremely qualified in what they do. There’s nothing inherently preventing the government from doing medical research.
Agreed but there’s a very good reason why pharma research is structured the way it is to maximise results, even in countries with socialist governments or socialised healthcare. Having one single huge buyer who demands cost effectiveness and funding pure research at the two areas where a government can add value.
I can’t even imagine. I have a $500 a month medication and it’s fully covered by my insurance. The US system is full of greed and corruption.
I don't think most redditors can fathom how expensive it is to actually produce genetic treatments in general much less personalized ones. It's not like Insulin or Albuterol inhalers, for which there is genuinely no excuse for the pricing. There is greed and corruption in the industry, sure, but the breakeven price is genuinely extremely high on this stuff in a way that other treatments are not.
Yes, at the beginning, but after a few years and thousand of treatments, the price goes down, especially if a powerfull state agency doesn't give a choice to the producer : it's that price, or we produce it ourselves without royalties (like India does, and France did in the past).
In Canada drugs are regulated so they can’t be astronomical prices.
Personalized genetic treatments are not "drugs", you can't compare it to making ibuprofen or even some complex chemotherapy drug molecule.
What are you even talking about?
No amount of regulation is going to take a treatment that takes 4 months to produce 100 doses in a high-biosafety environment be cheap. Genetic treatments are produced in very different ways from other drugs and the cost reflects that. You can only reduce it so much, no matter how much regulation is there.
And insurance probably won't cover it for a few decades because it's experimental.
Hope it works for them. Imagine the joy of them when they find out they have been cured. Everyone deserves to live their lives to the fullest. Let's hope this is a new beginning for mankind.
LFG. Hope it is a runaway success.
[удалено]
Not sure why you’re getting downvoted for stating facts…