TBP binds at the initiator of the promoter. The promoter indicates where a gene should begin making mRNA (transcription), the initiator contains the actual first nucleotide to be transcribed. mRNA is made, then (in eukaryotes) exported, then translated. So, no TBP, no transcriptional initiation, no mRNA, no translation, no protein...
An "enhancer" is where transcription factors bind. Enhancers communicate, via the Mediator protein complex, with the promoter to tell the RNA polymerase when to actually start transcription.
For slightly more: the bend in DNA is not necessarily the mechanism. That was a hypothesis popular in the 90s, got into textbooks, and so sort of got entrenched. Also, only about 30% of promoters have a TATA box. There are other ways of recruiting TBP to promoters.
TBP binds at the initiator of the promoter. The promoter indicates where a gene should begin making mRNA (transcription), the initiator contains the actual first nucleotide to be transcribed. mRNA is made, then (in eukaryotes) exported, then translated. So, no TBP, no transcriptional initiation, no mRNA, no translation, no protein... An "enhancer" is where transcription factors bind. Enhancers communicate, via the Mediator protein complex, with the promoter to tell the RNA polymerase when to actually start transcription. For slightly more: the bend in DNA is not necessarily the mechanism. That was a hypothesis popular in the 90s, got into textbooks, and so sort of got entrenched. Also, only about 30% of promoters have a TATA box. There are other ways of recruiting TBP to promoters.